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  • Analytical Chemistry and Spectroscopy  (78)
  • INSTRUMENTATION AND PHOTOGRAPHY  (38)
  • Biology
  • GENERAL
  • Life and Medical Sciences
  • 1975-1979  (142)
  • 1955-1959  (14)
  • 1978  (142)
  • 1958  (14)
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Keywords
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  • 1975-1979  (142)
  • 1955-1959  (14)
Year
  • 1
    Electronic Resource
    Electronic Resource
    A soft X-ray spectrometer for the study of plutonium and plutonium-based materialsWork performed under the auspices of the US Department of Energy by Lawrence Livermore Laboratory, under contract number W-7405-ENG-48. (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    X-Ray Spectrometry 7 (1978), S. 160-163 
    Details
    ISSN: 0049-8246
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A low-energy spectrometer for the X-ray analysis of plutonium and plutonium-containing materials has been built. We use ultra-thin window to maintain different pressures and contamination level in the spectrometers's sample and crystal chambers. Ultra-thin windows are also used on the X-ray tube and detector. Methods have been developed by which the spectrometer can analyze both metal and loose-powder samples. Representative calibration spectra are presented for the fluorine band in polyfluoroethylene, the oxygen band in α-Al2 O3, and the carbon band in graphite. Experimental spectra are presented for the fluorine band in PuF3 and for the oxygen ban in PuO2.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/xrs.1300070310
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of tobacco smoke on the metabolism and function of rat alveolar macrophagesPresented in part at the 1976 meeting of the American Society for Clinical Investigation (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 95 (1978), S. 105-113 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Alveolar macrophages harvested by bronchopulmonary lavage from rats exposed to tobacco smoke for 30 days (“smokers”) showed alterations in oxidative metabolism, lactate production and phagocytosis of inert starch particles when compared with control macrophages. Phagocytosis of viable Staphylococcus aureus was unaffected by tobacco smoke. Glucose oxidation measured by conversion of glucose-1-14C to 14CO2 was moderately affected while oxidation of glucose-6-14C to 14CO2 was not. Smokers routinely yielded fewer cells than controls, though these cells contained approximately 17% more protein than did controls. Opsonization of particles was not necessary for macrophages from either smoker or control animals to manifest a respiratory burst and increased superoxide and hydrogen peroxide release during phagocytosis. The glycolytic inhibitors, sodium fluoride and iodoacetamide, while effectively blocking glycolysis, did not inhibit phagocytosis by macrophages from either group. The results reported clearly distinguish alveolar macrophages from other phagocytic cells (peritoneal macrophages and polymorphonuclear leukocytes) and suggest a state of non-specific activation caused by exposure to tobacco smoke.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040950113
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  • 3
    Electronic Resource
    Electronic Resource
    Dissociation of plasminogen activator from the transformed phenotype in a 5-Bromodeoxyuridine dependent mutant of syrian hamster melanoma cells (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 95 (1978), S. 275-285 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The relationship between plasminogen activator levels and the expression of the transformed phenotype was studied in a 5-bromodeoxyuridine (BrdUrd) dependent mutant of Syrian hamster melanoma cells. In terms of cell morphology and cellular interactions, the BrdUrd dependent cells resemble transformed cells when grown in the presence of BrdUrd but resemble untransformed cells when grown in the absence of BrdUrd. It was found that the BrdUrd dependent cells release significant levels of plasminogen activator only when cultured in the absence of BrdUrd. In the presence of BrdUrd, the release of plasminogen activator by the dependent cells is suppressed, and the decreased level of plasminogen activator released in the presence of BrdUrd seems to be due to decreased production of active enzyme. Growth tests revealed that the BrdUrd dependent cells, when attached to a substrate, required BrdUrd in order to attain high densities. Furthermore, the cells are able to grow well in soft agar only in the presence of BrdUrd. These results suggest that the production and release of high levels of plasminogen activator are not related (either as cause or effect) to the expression of the transformed phenotype in the BrdUrd dependent cellsThe effect of dog serum (as a plasminogen source) on the BrdUrd dependent cells also was tested. It was found that cells cultured in medium containing dog serum exhibit a morphological alteration, but only in the absence of BrdUrd. The morphological response of the cells to dog serum resembles that previously observed with virus-transformed cells. In the BrdUrd dependent cells, the morphological response to dog serum appears correlated with the release of plasminogen activator but separated from other transformed characteristics.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040950305
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  • 4
    Electronic Resource
    Electronic Resource
    An immunocytochemical localization of the cortical granule lectin in fertilized and unfertilized eggs of xenopus laevis (1978)
    New York, NY : Wiley-Blackwell
    Gamete Research 1 (1978), S. 13-18 
    Details
    ISSN: 0148-7280
    Keywords: immunoperoxidase localization ; fertilization ; Xenopus laevis ; cortical reaction ; block to polyspermy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: At fertilization, the vitelline envelope surrounding the egg of Xenopus laevis is modified by the addition of an electron-dense component termed the “F layer.” The F layer functions as a block to polyspermy and as a block to the escape of macromolecules from the perivitelline space, thereby causing an osmotically driven envelope elevation. F-layer formation has been hypothesized to result from interaction between a cortical-granule lectin, released in the cortical reaction, and a jelly-coat ligand. Evidence for this hypothesis was sought by determining the location of the cortical-granule lectin both before and after fertilization, using a specific antibody conjugated to horseradish peroxidase. The cortical-granule lectin was localized only in the cortical granules of the unfertilized egg and was located predominantly in the perivitelline space and the F layer of a fertilized egg. These observations support the hypothesis that the F layer is formed by a cortical-granule-Iectin-jelly layer-ligand interaction.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120010104
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  • 5
    Electronic Resource
    Electronic Resource
    Identification of 4,6-O-(1-carboxyethylidene)-D-galactose by combined gas chromatogrphy mass spectrometry (1978)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 5 (1978), S. 671-673 
    Details
    ISSN: 0306-042X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Combined gas chromatography mass spectrometry was used to separate and identify a carrageenan component suspected of being the acid ketal 4,6-O-(1-carboxyethylidene)-D-galactose. The mass spectral fragmentation pattern is presented as evidence for the presence of this component in the carrageenan from Petrocelis middendorfii (P. francisana).
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200051207
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  • 6
    Electronic Resource
    Electronic Resource
    A carbon-13 nuclear magnetic resonance spectral data base and search system (1978)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 11 (1978), S. 535-540 
    Details
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A data base containing approximately 4000 13C nuclear magnetic resonance spectra has been assembled. The spectra have been evaluated and all the corresponding compounds have been registered by the Chemical Abstracts Service (CAS). The data base is available to the international scientific community on magnetic tape or microfiche and is also the basis of a search system operating upon an international computer network.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1270111102
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  • 7
    Electronic Resource
    Electronic Resource
    Electron impact spectra of 2-diazoacetophenones (1978)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 13 (1978), S. 39-42 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectra of nine 2-diazoacetophenones are reported. Rearrangements are examined by means of low electron voltage measurements, deuterium labelling and high resolution studies.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210130110
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  • 8
    Electronic Resource
    Electronic Resource
    Cage compounds IVFor Part III see, Ref. 1.. 1H and 13C NMR study of 3,6-epoxypentacyclo-[6.2.2.02,7.04,10.05,9]dodecane and 3,6-epoxypentacyclo-[6.2.1.02,7.04,10.05,9]undecane (1978)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 11 (1978), S. 520-523 
    Details
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The complete 1H and 13C NMR assignments for 3,6-epoxypentacyclo[6.2.2.02,7.04,10.05,9]dodecane and 3,6-epoxypentacyclo[6.2.1.02,7.04,10.05,9]undecane are reported. The difference between the 1H and 13C chemical shifts and one-bond proton-carbon coupling constants of these two compounds are adequately explained by the difference in the hybridization of the C—H bonds.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1270111010
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  • 9
    Electronic Resource
    Electronic Resource
    Chemical ionization mass spectra of some 2-norbornyl derivatives (1978)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 13 (1978), S. 163-166 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Chemical ionization mass spectra of exo- and endo-2-norbornanols and their phenylurethane derivatives have been obtained with several reactant ions. Small differences are noted in the abundances of norbornyl and [M+H]+ ions for the phenylurethane derivatives: more norbornyl ions with the exo compounds. Relative rate constants for decomposition of [M+H]+ ions, kexo/kendo ≅ 1-2. No evidence was found for s̰-participation in the decomposition of these ions. The i-C4H10 chemical ionization spectrum of endo-2-norbornanol contains a much greater abundance of [M-H]+ ions than the i-C4H10 chemical ionization spectrum of exo-2-norbornanol. This difference presumably results from steric hindrance toward attack of the endo hydrogen.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210130309
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  • 10
    Electronic Resource
    Electronic Resource
    Ionen-Cyclotron-Resonanzuntersuchungen an Ionen-Molekül-Komplexen von Anisol und Anisolhomologen (1978)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 13 (1978), S. 397-401 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: The ion cyclotron resonance spectra of anisol, 3-methylanisol, phenetol, 3-methylphenetol and thioanisol at pressures of 10-6 Torr resemble the normal mass spectra. Above 10-5 Torr the spectra show signals due to product ions. As seen from double resonance measurements most product ions are formed by the reaction of a fragment ion with a neutral ether molecule under elimination of alkyl, alkoxy alkylthioradicals or of ethylene. Apart from the molecular ion radical ions do not participate in ion-molecule reactions.
    Notes: Die ICR-Spektren von Anisol, 3-Methylanisol, Phenetol, 3-Methylphenetol und Thioanisol, die bei 10-6 Torr weitgehend mit den normalen Massenspektren übereinstimmen, zeigen oberhalb von 10-5 Torr zahlreiche Signale von Produktionen. Doppelresonanzmessungen ergaben, daß die meisten Produktionen durch Reaktion eines Fragmentions mit einem Äthermolekül unter Abspaltung eines Alkyl-, Alkoxy- oder Thioalkylradikals bzw. von Äthylen entstanden sind. Daneben finden sich einzelene Produktionen (möglicher-weise Ion-Molekül-Komplexe), die durch Zusammentreten von Ionen mit Äthermolekülen ohne Eliminierung entstanden sind. Radikalionen, mit Ausnahme des Molekular ions, nehmen nicht an den Ionen-Molekül-Reaktionen teil.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210130707
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