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  • Life and Medical Sciences
  • 1980-1984
  • 1970-1974
  • 1965-1969  (27)
  • 1960-1964
  • 1940-1944  (7)
  • 1968  (10)
  • 1967  (17)
  • 1943  (7)
Collection
Publisher
Years
  • 1980-1984
  • 1970-1974
  • 1965-1969  (27)
  • 1960-1964
  • 1940-1944  (7)
Year
  • 1
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The cellular and subcellular events in the anamnestic response were considered. Rabbits previously immunized with key hole limpet hemocyanin (KLH) were given an anamnestic challenge in the hind footpads. The popliteal lymph nodes were removed at intervals after immunization and the following correlated on a temporal basis: the changes in the number and types of cells in the lymph nodes; the formation and regression of ribosomes, polyribosomes, endoplasmic reticulum and Golgi apparatus in plasma cells; the changes in intracellular immunofluorescence for anti-hemocyanin; and, the incorporation of 14C labeled amino acids by lymph node cells into anti-KLH during a brief in vitro culture period.Maximum intracellular fluorescence for anti-KLH and the largest incorporation of 14C labeled amino acids into antibody occurred between the third and fourth day after immunization. During this interval highly differentiated plasma cells were most numerous with respect to the total cellular population. These events took place in a 12 to 24 hour period.This was followed by an abrupt decline in the synthesis of antibody. Coincident with this was a reduction in the number of recognizable plasma cells in the nodes, diminished intracellular fluorescence for anti-KLH and a simplification of the cytoplasm of the plasma cells toward a lymphocytic form.
    Additional Material: 9 Ill.
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 72 (1968), S. 219-230 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Fifteen alcohol-soluble carbohydrates have been isolated from logphase cultures of Tetrahymena. Preliminary results obtained by parallel chromatography of impure extracts indicate that some of the soluble components were 2-D-deoxyribose, ribose, mannose, fructose, arabinose, xylose, and glucose. Another elution gradient with extracts from cells washed several times, indicates that maltose and glucose were the only identifiable components as compared with 18 known standards. Differences were observed in the alcohol-soluble carbohydrate content in log-phase versus stationary-phase cells. For example, it is clearly indicated that component 13 is missing in stationary-phase cells while component 15 is missing in log-phase cells. Fifteen alcohol-soluble carbohydrates have been chromatographed from synchronized cells. All of these compounds show cyclic variation in relation to cell division. Component 13 accumulates in cells blocked in morphogenesis and decreases as oral development proceeds in synchronized cells.
    Additional Material: 5 Ill.
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  • 4
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Experiments will be described which demonstrate that the product of purified “Qβ-replicase” is fully competent to serve both as a template and as a program for the synthesis of complete virus particles. The use of mutant RNA has permitted the demonstration that nucleic acid is the instructive agent in the replication process and hence satisfies the definition of a self-duplicating entity. Methods have been devised to examine the product both physically and biologically with a minimum of manipulation and with complete recovery of product and input template. A detailed analysis of every interval of synthesis has thus become possible. These technical advances have permitted us to demonstrate the existence of a latent period prior to the appearance of the first new complete infectious RNA molecules. Further, this latent period is accompanied by an eclipse of the input templates as infectious agents. The use of electrophoretic separation on acrylamide gels has yielded a detailed account of both templates and early product during the latent period, with the consequent identification of the intermediate stages. The resulting data and their implications for the mechanism of RNA replication will be discussed.
    Additional Material: 29 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 72 (1943), S. 279-303 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 1 Tab.
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 123 (1967), S. 1-16 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A theoretical analysis is made of the mechanical advantages of exoskeletons and endoskeletons. More complicated and realistic loading systems are considered than have been by previous authors. For all cases involving static loading, an exoskeleton would seem to be advantageous, but sometimes the advantage is quite small. If impact is considered, the advantage of exoskeletons becomes very much reduced, even on theoretical calculations; and it is likely that in life the advantage may be converted to a disadvantage, particularly in large active animals such as vertebrates.
    Additional Material: 6 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 121 (1967), S. 19-28 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In the column of hydra, tissues continually move away from a region located just underthe whorl of tentacles. Above this subtentacular region, tissues proceed into the hypostome and tentacles; below it tissues pass into the buds or continue down the stalk. These movements represent a steady state pattern of tissue renewal in which column growth is balanced by tissue loss at the body extremities. But the existence of a subtentacular zone in which tissue appears stationary does not necessarily indicate that growth is restrictedto this region, as is commonly stated.The body column of hydra can be viewed as an expanding cylinder whose elongation is balanced by tissue loss at the two ends. In such a body there must be one region from whichtissue appears to emanate, regardless of how growth is distributed along the cylinder. Only the rates at which tissues move will be characteristic of the underlying growthpattern. In Hydra littoralis, the measured rates of tissue movement down the gastric column are consistent with the distributions of mitotic figures, which indicate that growth is spread out along the column.
    Additional Material: 9 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 124 (1968), S. 313-320 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Forty-two unselected ovaries from adult mares were examined histologically, and with histochemical methods for mucins. A considerable part of the surface of the ovulation fossa was directly covered by columnar epithelium, with many ciliated cells. This epithelium, which was distributed mainly on the anterior side of the ovulation fossa, closely resembled the contiguous epithelium of the infundibulum of the oviduct, was frequently folded, and gave rise to short clefts projecting into the ovarian substance. The remainder of the ovulation fossa was covered by non-ciliated, low cuboidal or squamous epithelium, lacking folds or clefts.“Fossa cysts,” up to 6.5 mm in diameter, were observed in the ovarian tissue around the ovulation fossa in 27 (64%) of these ovaries. Both simple and branched, tubular and vesicular forms were present, and all were blind-ending. Their epithelial lining cells, which varied from simple squamous to columnar in type, were frequently ciliated. Many fossa cysts contained secretions histochemically similar to those of the columnar epithelium of the ovulation fossa and infundibulum. Both sialic acidcontaining and neutral mucins were present. It is suggested that these cysts were probably derived by ingrowth from the columnar epithelium of the ovulation fossa. This epithelium may be of müllerian duct origin.
    Additional Material: 9 Ill.
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 72 (1943), S. 561-587 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 4 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 122 (1967), S. 169-173 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Histological examination of the fibrous and cellular connective tissue components of the periodontal ligament in the Caiman and the Alligator reveals the presence of reticular fibrillae, collagenic, elastic, and oxytalan fibers, as well as fibrocytes, osteoblasts, cementoblasts and epithelial rests. The oxytalan fibers differentiated by the peracetic acid aldehyde-fuchsin method are most numerous in the coronal region, radiating from the primary cementum into the periodontal ligament a short distance. Oxytalan fibers in fewer numbers are found interspersed between the oblique and the horizontal principal fiber bundles. Inasmuch as the crocodilian teeth have continuous replacement and thus a relatively short functional life, the oxytalan fibers of the Caiman and the Alligator appear to be proportionally fewer in number than they are in the mammalian periodontal tissues. The presence of the oxytalan fibers and epithelial rests in the Order Crocodilia (Crocodilia) adds to the number of dental structures shared with the Class Mammalia (Mammalia) (mammals) such as a stellate reticulum, a primary and secondary cementum and a periodontal ligament. This furnishes additional histological evidence for evaluation of the phylogenetic position of this group.
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