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  • Life and Medical Sciences  (44)
  • Chemiluminescence  (1)
  • Wiley-Blackwell  (45)
  • Cambridge University Press
  • Institute of Physics
  • International Union of Crystallography
  • Nature Publishing Group
  • Oxford University Press
  • 2020-2024
  • 2020-2022
  • 1985-1989
  • 1965-1969  (40)
  • 1955-1959
  • 1945-1949
  • 1940-1944  (5)
  • 1935-1939
  • 1967  (17)
  • 1965  (23)
  • 1942  (5)
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  • Wiley-Blackwell  (45)
  • Cambridge University Press
  • Institute of Physics
  • International Union of Crystallography
  • Nature Publishing Group
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  • 2020-2024
  • 2020-2022
  • 1985-1989
  • 1965-1969  (40)
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  • 1
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Fifteen alcohol-soluble carbohydrates have been isolated from logphase cultures of Tetrahymena. Preliminary results obtained by parallel chromatography of impure extracts indicate that some of the soluble components were 2-D-deoxyribose, ribose, mannose, fructose, arabinose, xylose, and glucose. Another elution gradient with extracts from cells washed several times, indicates that maltose and glucose were the only identifiable components as compared with 18 known standards. Differences were observed in the alcohol-soluble carbohydrate content in log-phase versus stationary-phase cells. For example, it is clearly indicated that component 13 is missing in stationary-phase cells while component 15 is missing in log-phase cells. Fifteen alcohol-soluble carbohydrates have been chromatographed from synchronized cells. All of these compounds show cyclic variation in relation to cell division. Component 13 accumulates in cells blocked in morphogenesis and decreases as oral development proceeds in synchronized cells.
    Additional Material: 5 Ill.
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  • 2
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Experiments will be described which demonstrate that the product of purified “Qβ-replicase” is fully competent to serve both as a template and as a program for the synthesis of complete virus particles. The use of mutant RNA has permitted the demonstration that nucleic acid is the instructive agent in the replication process and hence satisfies the definition of a self-duplicating entity. Methods have been devised to examine the product both physically and biologically with a minimum of manipulation and with complete recovery of product and input template. A detailed analysis of every interval of synthesis has thus become possible. These technical advances have permitted us to demonstrate the existence of a latent period prior to the appearance of the first new complete infectious RNA molecules. Further, this latent period is accompanied by an eclipse of the input templates as infectious agents. The use of electrophoretic separation on acrylamide gels has yielded a detailed account of both templates and early product during the latent period, with the consequent identification of the intermediate stages. The resulting data and their implications for the mechanism of RNA replication will be discussed.
    Additional Material: 29 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Philadelphia : Wiley-Blackwell
    Journal of Cellular and Comparative Physiology 20 (1942), S. 151-168 
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 7 Ill.
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  • 4
    Electronic Resource
    Electronic Resource
    Philadelphia : Wiley-Blackwell
    Journal of Cellular and Comparative Physiology 65 (1965), S. 141-153 
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: An effort has been made to ascertain the site of calcium uptake in rabbit psoas muscle by electron microscopy. Following a brief glycerol extraction, small groups of fibers were exposed in a suitable electrolyte environment to calcium and ATP. Conditions were such that calcium was accumulated as an insoluble oxalate salt. Conventional preparatory procedures for electron microscopy were modified so that the calcium oxalate deposits were retained in situ in ultrathin sections. These were found localized in the longitudinal component of the sarcoplasmic reticulum including the terminal dilatations which form the outer elements of the triads. The possible participation of the intermediate element of the triad in the uptake of calcium could not be determined. The results are regarded as direct evidence that the sarcoplasmic reticulum is intimately concerned with the uptake and release of calcium associated with the contraction-relaxation cycle.
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 123 (1967), S. 1-16 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A theoretical analysis is made of the mechanical advantages of exoskeletons and endoskeletons. More complicated and realistic loading systems are considered than have been by previous authors. For all cases involving static loading, an exoskeleton would seem to be advantageous, but sometimes the advantage is quite small. If impact is considered, the advantage of exoskeletons becomes very much reduced, even on theoretical calculations; and it is likely that in life the advantage may be converted to a disadvantage, particularly in large active animals such as vertebrates.
    Additional Material: 6 Ill.
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 121 (1967), S. 19-28 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In the column of hydra, tissues continually move away from a region located just underthe whorl of tentacles. Above this subtentacular region, tissues proceed into the hypostome and tentacles; below it tissues pass into the buds or continue down the stalk. These movements represent a steady state pattern of tissue renewal in which column growth is balanced by tissue loss at the body extremities. But the existence of a subtentacular zone in which tissue appears stationary does not necessarily indicate that growth is restrictedto this region, as is commonly stated.The body column of hydra can be viewed as an expanding cylinder whose elongation is balanced by tissue loss at the two ends. In such a body there must be one region from whichtissue appears to emanate, regardless of how growth is distributed along the cylinder. Only the rates at which tissues move will be characteristic of the underlying growthpattern. In Hydra littoralis, the measured rates of tissue movement down the gastric column are consistent with the distributions of mitotic figures, which indicate that growth is spread out along the column.
    Additional Material: 9 Ill.
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  • 7
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Implants were made into forelimbs of Triturus viridescens using fresh, frozen and boiled kidney and liver of T. viridescens and R. pipiens. Limbs were recovered at intervals up to 70 days post-implantation.Kidney implants from Wisconsin R. pipiens gave twice as many extensive accessory structures as did Vermont frog kidney. Total induction percentages, however, were similar.Quantitative and qualitative parameters for implant-induction of accessory structures were investigated. The decrease in antigenicity and increased rate of cytolysis of frozen implants resulted in increased similarity between frog and newt kidney in rate and pattern of breakdown and in rates of induction. Modification of rate and duration of the release of the stimulating factor from the implant did not result in induction by liver implants.No evidence was found for any increase in innervation prior to or coincident with blastema formation. Implantation and implant cytolysis may cause hypersensitivity of limb tissues to the normal innervation pattern or trophic stimuli from the implant may act with those from the injured limb tissues to produce growth.The general pattern of host reaction to the implanted material was studied and described.
    Additional Material: 1 Ill.
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  • 8
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The muscles and motor and sensory nerves of the pregenital abdominal segments were described and discussed in relation to the nerves and muscles of the thorax, as described by other workers. Each of the integumental muscles was named and described with regard to its location, function and innervation. Differences among segments of the same sex and between sexes were noted.A description of a longitudinal muscle, named here the hyperneural muscle, was included. The muscle overlies the abdominal portion of the nerve cord and may be derived from the ventral diaphragm. The most notable features of its structure are chiasmata of fibers which occur at points along its length and which show consistent relationships to the nerve cord and median nerve.A previously undescribed organ, located ventrally at the intersegmental fold, having dual innervation and showing stretch receptor function was described.
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 70 (1942), S. 41-67 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 1 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 122 (1967), S. 169-173 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Histological examination of the fibrous and cellular connective tissue components of the periodontal ligament in the Caiman and the Alligator reveals the presence of reticular fibrillae, collagenic, elastic, and oxytalan fibers, as well as fibrocytes, osteoblasts, cementoblasts and epithelial rests. The oxytalan fibers differentiated by the peracetic acid aldehyde-fuchsin method are most numerous in the coronal region, radiating from the primary cementum into the periodontal ligament a short distance. Oxytalan fibers in fewer numbers are found interspersed between the oblique and the horizontal principal fiber bundles. Inasmuch as the crocodilian teeth have continuous replacement and thus a relatively short functional life, the oxytalan fibers of the Caiman and the Alligator appear to be proportionally fewer in number than they are in the mammalian periodontal tissues. The presence of the oxytalan fibers and epithelial rests in the Order Crocodilia (Crocodilia) adds to the number of dental structures shared with the Class Mammalia (Mammalia) (mammals) such as a stellate reticulum, a primary and secondary cementum and a periodontal ligament. This furnishes additional histological evidence for evaluation of the phylogenetic position of this group.
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