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  • Polymer and Materials Science  (409)
  • ASTRONOMY  (161)
  • Life and Medical Sciences  (127)
  • Mathematics and Statistics
  • 1990-1994  (704)
  • 1980-1984
  • 1940-1944
  • 1915-1919  (1)
  • 1994  (704)
  • 1916  (1)
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  • 1990-1994  (704)
  • 1980-1984
  • 1940-1944
  • 1915-1919  (1)
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  • 1
    Publication Date: 2019-08-28
    Description: Gamma-ray observations of the nearby starburst galaxies NGC 253 and M82 over the energy range (0.05-10) MeV have been obtained with the Oriented Scintillation Spectrometer Experiment (OSSE) spectrometer on the Compton Gamma-Ray Observatory (CGRO). The priority of these galaxies as OSSE targets had been established on the grounds that the average supernova rate may be high in starbursts as indicated by infrared and radio observations, and at distances of approximately 3 Mpc a significant chance of supernova gamm-ray line detection exists. NGC 253 was detected in continuum emission up to 165 keV with a total significance of 4.4 sigma and an estimated luminosity of 3 x 10(exp 40) ergs/s. The spectrum is best fit by a power law of photon index approximately 2.5. We consider the possible contribution of different emission mechanisms, including inverse Compton scattering, bremsstrahlung, discrete sources, and Type Ia/Ib supernova continuum to the measured flux. No significant continuum flux was observed from M82. A search for the gamma-ray line from the decay of the most abundant radioactive element produced in supernovae (Ni-56 yields Co-56 yields Fe-56) yielded no significant detection: the 3 sigma upper limits to the line fluxes at 0.158, 0.812, 0.847, and 1.238 MeV for both galaxies are obtained.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 437; 1; p. 173-178
    Format: text
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  • 2
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 56 (1994), S. 331-339 
    ISSN: 0730-2312
    Keywords: 1,25-(OH)2D3 ; 24,25-(OH)2D3 ; matrix vesicles ; nongenomic regulation ; extracellular matrix ; alkaline phosphatase ; phospholipase A2 ; Protein kinase C ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Vitamin D metabolites appear to regulate chondrocytes and osteoblasts via a combination of genomic and nongenomic mechanisms. Specificity of the nongenomic response to either 1,25-(OH)2D3 or 24, 25-(OH)2D3 may be conferred by the chemical composition of the target membrane and its fluid mosaic structure, by the presence of specific membrane receptors, or by the interaction with classic Vitamin D receptors. Nongenomic effects have been shown to include changes in membrane fluidity, fatty acid acylation and reacylation, arachidonic acid metabolism and prostaglandin production, calcium ion flux, and protein kinaase C activity. Chondrocytes metabolize 25-(OH)D3 to 1,25-(OH)2D3 and 24,25-(OH)2D3; production of these metabolites is regulated by both growth factors and hormones and is dependent on the state of cell maturation. 1,25-(OH)2D3 and 24,25-(OH)2D3 may interact directly with extracellular matix vesicles to regulate their function in the matrix, including protease activity, resulting in matrix modefication and calcification. Isolated matrix vesicles, produced by growth zone chondrocytes, can activate latent transforming growth factor-β when incubated with exogenous 1,25-(OH)2D3. These observations suggest that nongenomic regulation of martix vesicle structure and function may be a mechanism by which mesenchymal cells, like osteoblasts and chndrocytes, may modulate events in the extracellular matrix at sites distant from the cell surace.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The need for alternatives to autogenous bone grafts is widely recognized. This study compared the torsional strength of canine femora 1 year after grafting with one of three forms of a collagen/hydroxyapatite/tricalcium phosphate bone grafting material (COLLAGRAFT15), autogenous bone, or no graft. The groups were compared to each other and to the unoperated contralateral femora. Results of torsional testing were evaluated for torsional strength, torsional displacement, total energy to fracture and White fracture mode. Data analysis showed lower torsional strength of the operated vs. unoperated femora with the exception of morsellized COLLAGRAFT15 material, which had higher strength. However, the only difference in the operated groups was that the morsellized COLLAGRAFT15 had greater strength than several groups including the autogenous bone group. There was no difference found in angular displacement between any of the groups. However, there was a difference in the energy to fracture in both strip forms of the COLLAGRAFT15. The final conclusion is that in this model, grafting with COLLAGRAFT15 provided torsional properties at one year postoperatively at least equivalent to autogenous bone. © 1994 John Wiley & Sons, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 28 (1994), S. 405-405 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Secondary ion mass spectrometry has been used to identify the presence of Cu contamination on undoped semiinsulating GaAs wafer surfaces following polishing under certain conditions. The presence of a contaminating species on the wafer surface is indicated by the influence of pre-etch treatments on electrical measurements performed on heat-treated wafers, with and without Si implants. The identification of Cu as a contaminant is confirmed by photoluminescence measurements. With the appropriate wafer preparation process, the level of Cu contamination is below the SIMS detection limit of 〈1 × 1016 atoms cm-3.In the SIMS analysis of the surface-contaminated wafers, the Cu depth profile shape was dependent on the primary beam bombardment energy, suggesting a chemical segregation of Cu out of the altered layer, a redistribution that is known to occur in Si.To quantify the surface concentration of Cu, GaAs wafers were deliberately contaminated with Cu, heat treated and analysed with glow discharge mass spectrometry and SIMS to provide a cross-calibration.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0749-503X
    Keywords: Hansenula ; haemoglobin ; integration ; continuous culture ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Recombinant human haemoglobin A (rHbA) was produced by a leucine-requiring strain of Hansenula polymorpha which had been transformed with an integration vector containing the Saccharomyces cerevisiae LEU2 gene and cDNAs for the expression of α and β globin each driven by the H. polymorpha MOX promoter. After 40 generations in a chemostat it was found that the integrated vector had become amplified in the host strain. In some cases this led to an increase in LEU2 gene dosage, but a loss of globin expression cassettes. In other cases the globin gene dosage also increased. These changes coincided with an increase in rHbA production in the culture, which was reversed when the dilution rate was increased. Isolates from a chemostat culture producing elevated levels of rHbA were grown in fed-batch fermentations, resulting in higher productivities than when inoculated with the parent strain. The rHbA produced was purified and characterized. Oxygen binding studies and electrospray mass spectrometry showed that the rHbA had been processed and assembled correctly, and behaved as a fully functional co-operative tetramer.
    Additional Material: 7 Ill.
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  • 7
    Publication Date: 2019-01-25
    Description: The bright, peculiar elliptical galaxy Centaurus A (NGC 5128, PKS 1322-427) was one of the first extragalactic radio sources to be optically identified (Bolton et al. 1949). At a distance of 4 Mpc, Centaurus A is the closest active radio galaxy and affords the highest linear imaging resolution (1 mas approximately equal to 0.02 pc) and hence the best prospects for studying an active nucleus close to the central radio source. We present the results of multi-epoch, 8.4-GHz, very long baseline interferometry (VLBI), imaging observations of the nucleus made over the past three years. The nucleus possesses a core-jet structure where the inner portion of the jet shows apparent linear motion with a velocity substantially less than the speed of light.
    Keywords: ASTRONOMY
    Type: Australian Journal of Physics (ISSN 0004-9506); 47; 5; p. 619-624
    Format: text
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  • 8
    Publication Date: 2019-08-28
    Description: We present the first Extreme Ultraviolet Explorer (EUVE) satellite observation of the Jupiter system, obtained during the 2 day period 1993 March 30 through April 1, which shows a rich emission-line spectrum from the Io plasma torus spanning wavelengths 370 to 735 A. The emission features correspond primarily to known multiplets of oxygen and sulfur ions, but a blended feature near 372 A is a plausible Na II transition. The summed detected energy flux of (7.2 +/- 0.2) x 10(exp -11) ergs/sq cm(s) corresponds to a radiated power of approximately equal to 4 x 10(exp 11) W in this spectral range. All ansa emissions show a distinct dawn-dusk brightness asymmetry and the measured dusk/dawn ratio of the bright S III lambda-680 feature is 2.3 +/- 0.3, significantly larger than the ratio measured by the Voyager spacecraft ultraviolet (UV) instruments. A preliminary estimate of ion partitioning indicates that the oxygen/sulfur ion ratio is approximately equal to 2, compared to the value approximately equal to 1.3 measured by Voyager, and that (Na(+))/(e) greater than 0.01.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 426; 1; p. L51-L54
    Format: text
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  • 9
    Publication Date: 2019-08-28
    Description: We have used the Faint Object Spectrograph of the Hubble Space Telescope to observe interstellar linear polarization from 1300 to 3300 A in two stars with well-studied interstellar polarization at visible wavelenths. The wavelength dependence of linear polarization declines smoothly with decreasing wavelength and is devoid of structure associated with the prominent 2175 A absorption bump in the interstellar extinction curve. The data for one star (HD 161056) are consistent with an extrapolation based on the Serkowski formula of a fit to the ground-based polariztion; the other star (HD 7252) shows excess (super-Serkowski) polarization relative to the extrapolation. Out of a total of 10 stars now studied by means of spectropolarimetry in the satellite ultraviolet, including eight obseved with the Wisconsin Ultraviolet Photopolarimeter, five (those of longest lambda (sub max)) show Serkowski behavior, and four others show super-Serkowski behavior; only one (HD 197770) shows evidence for polarization associated with the 2175 A bump. These results place important constraints on the nature of the bump feature.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 427; 1; p. L47-L50
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  • 10
    Publication Date: 2019-06-28
    Description: We present the data and initial results from a combined HST/IUE/ground-based spectroscopic monitoring campaign on the Seyfert 1 galaxy NGC 5548 that was undertaken in order to address questions that require both higher temporal resolution and higher signal-to-noise ratios than were obtained in our previous multiwavelength monitoring of this galaxy in 1988-89. IUE spectra were obtained once every two days for a period of 74 days beginning on 14 March 1993. During the last 39 days of this campaign, spectroscopic observations were also made with the HST Faint Object Spectrograph (FOS) on a daily basis. Ground-based observations, consisting of 165 optical spectra and 77 photometric observations (both CCD imaging and aperture photometry), are reported for the period 1992 October to 1993 September, although much of the data are concentrated around the time of the satellite-based program. These data constitute a fifth year of intensive optical monitoring of this galaxy. In this contribution, we describe the acquisition and reduction of all of the satellite and ground-based data obtained in this program. We describe in detail various photometric problems with the FOS and explain how we identified and corrected for various anomalies. During the HST portion of the monitoring campaign, the 1350 A continuum flux is found to have varied by nearly a factor of two. In other wavebands, the continuum shows nearly identical behavior, except that the amplitude of variability is larger at shorter wavelengths, and the continuum light curves appear to show more short time-scale variability at shorter wavelengths. The broad emission lines also vary in flux, with amplitudes that are slightly smaller than the UV continuum variations and with a small time delay relative to the UV continuum. On the basis of simple time-series analysis of the UV and optical continuum and emission line light curves, we find (1) that the ultraviolet and optical continuum variations are virtually simultaneous, with any lag between the 1350 A continuum and the 5100 A continuum amounting to less than about one day; (2) that the variations in the highest ionization lines observed, He II lambda 1640 and N V lambda 1240, lag behind the continuum variations by somewhat less than 2 days, and (3) that the velocity field of the C IV-emitting region is not dominated by radial motion. The results on the C IV velocity field are preliminary and quite uncertain, but there are some weak indications that the emission-line (wings absolute value of Delta upsilon is greater than or equal to 3000 km/s) respond to continuum variations slightly more rapidly than does the core. The optical observations show that the variations in the broad H beta line flux follow the continuum variations with a time lag of around two weeks, about twice the lag for Ly alpha and C IV, as in our previous monitoring campaign on this same galaxy. However, the lags measured for Ly alpha, C IV, and H Beta are each slightly smaller than previously determined. We confirm two trends reported earlier, namely (1) that the UV/optical continuum becomes 'harder' as it gets brighter, and (2) that the highest ionization emission lines have the shortest lags, thus indicating radial ionization stratificatin of a broad-line region that spans over an order of magnitude range in radius.
    Keywords: ASTRONOMY
    Type: NASA-CR-199341 , NAS 1.26:199341
    Format: application/pdf
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