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  • Articles  (76)
  • 1995-1999  (72)
  • 1970-1974
  • 1905-1909  (4)
  • 1999  (72)
  • 1906  (4)
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  • 1995-1999  (72)
  • 1970-1974
  • 1905-1909  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    CHEMISTRY OF THE ALBUMENS. (1906)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 28 (1906), S. 658-660 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01971a019
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  • 2
    Electronic Resource
    Electronic Resource
    CHEMISTRY OF THE PROTEIDS. (1906)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 28 (1906), S. 911-913 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01973a013
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  • 3
    Electronic Resource
    Electronic Resource
    ESTIMATING ATRAZINE LEACHING IN THE MIDWEST (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 35 (1999), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: Data from seven Management Systems Evaluation Areas (MSEA) were used to test the sensitivity of a leaching model, Pesticide Root Zone Model-2, to a variety of hydrologic settings in the Midwest. Atrazine leaching was simulated because it was prevalent in the MSEA studies and is frequently detected in the region's groundwater. Short-term simulations used site specific soil and chemical parameters. Generalized simulations used data avail. able from regional soil databases and standardized variables. Accurate short-term simulations were precluded by lack of antecedent atrazine concentrations in the soil profile and water, suggesting that simulations using data for less than five years underestimate atrazine leaching. The seven sites were ranked in order of atrazine detection frequency (concentration 〉 0.2 μg L-1) in soil water at 2 m depth in simulations. The rank order of the sites based on long-term simulations were similar to the ranks of sites based on atrazine detection frequency from groundwater monitoring. Simulations with Map Unit Use File (MUUF) soils data were more highly correlated with ranks of observed atrazine detection frequencies than were short-term simulations using site-specific soil data. Simulations using the MIJUIF data for soil parameters were sufficiently similarity to observed atrazine detection to allow the credible use of regional soils data for simulating leaching with PRZM-2 in a variety of Midwest soil and hydrologic conditions. This is encouraging for regional modeling efforts because soil parameters are among the most critical for operating PRZM-2 and many other leaching models.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.1999.tb04196.x
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  • 4
    Electronic Resource
    Electronic Resource
    Ultraviolet-B-induced stress and changes in gene expression in Arabidopsis thaliana: role of signalling pathways controlled by jasmonic acid, ethylene and reactive oxygen species (1999)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 22 (1999), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Treatment with supplementary UV-B resulted in decreases in transcripts of the photosynthetic genes Lhcb and psbA and concomitant increase in transcripts of two pathogen-related genes, PR-1 and PDF1·2, in Arabidopsis thaliana. UV-B exposure caused increases in jasmonic acid (JA) levels and ethylene production. UV-B treatment of jar1 and etr1-1 mutants, which are insensitive to JA and ethylene, respectively, showed that the increase in PR-1 transcripts was dependent on ethylene and PDF1·2 transcripts on both JA and ethylene. In contrast, the down-regulation of photosynthetic transcripts was independent of both compounds. Previous studies have indicated a role for reactive oxygen species (ROS) in the UV-B-induced down-regulation of the photosynthetic genes and up-regulation of PR-1 genes. Here we have shown that ROS are also required for the UV-B-induced up-regulation of PDF1·2 genes. The results indicate that the effects of UV-B on the three sets of genes are mediated through three distinct signal transduction pathways which are similar, but not identical, to pathways initiated in response to pathogen infection. In addition, the increased sensitivity of both jar1 and etr1-1 mutants to UV-B radiation, as compared with wild-type plants, indicated that intact JA and ethylene signal pathways are required for defence against UV-B damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.1999.00499.x
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  • 5
    Electronic Resource
    Electronic Resource
    Making sense out of sound (1999)
    [s.l.] : Nature America Inc.
    Nature genetics 21 (1999), S. 347-349 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Sound is a well-understood, physical phenomenon. How we perceive sound and make sense of complex auditory stimuli is a different matter altogether. Genetic approaches, however, have provided a powerful strategy to dissect auditory function and to some extent, overcome the challenge posed by the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/7668
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  • 6
    Electronic Resource
    Electronic Resource
    Multivariate nonhomogeneous refinement equations (1999)
    Springer
    The journal of Fourier analysis and applications 5 (1999), S. 589-597 
    Details
    ISSN: 1531-5851
    Keywords: 42C15 ; 39B99 ; multivariate ; nonhomogeneous ; refinement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We give necessary and sufficient conditions for the existence and uniqueness of compactly supported distribution solutionsf=(f 1,...,f r)T of nonhomogeneous refinement equations of the form $$f(x) = h(x) + \sum\limits_{\alpha \in A} {c_\alpha f(2x - \alpha )(x \in R^s )} $$ , where h=(h1,...,hr)Tis a compactly supported vector-valued multivariate distribution, A⊂Z+ s has compact support, and the coefficientsc α are real-valued r×r matrices. In particular, we find a finite dimensional matrix B, constructed from the coefficientsc α of the equation (I−B)q=p, where the vectorp depends on h. Our proofs proceed in the time domain and allow us to represent each solution regardless of the spectral radius of P(0):=2−s∑c α , which has been a difficulty in previous investigations of this nature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01257193
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  • 7
    Electronic Resource
    Electronic Resource
    Enhanced Evolvability in Immunoglobulin V Genes Under Somatic Hypermutation (1999)
    Springer
    Journal of molecular evolution 49 (1999), S. 23-26 
    Details
    ISSN: 1432-1432
    Keywords: Key words: Genome evolution — Adaptability — Somatic hypermutation — Affinity maturation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. Darwinian theory requires that mutations be produced in a nonanticipatory manner; it is nonetheless consistent to suggest that mutations that have repeatedly led to nonviable phenotypes would be introduced less frequently than others—if under appropriate genetic control. Immunoglobulins produced during infection acquire point mutations that are subsequently selected for improved binding to the eliciting antigen. We and others have speculated that an enhancement of mutability in the complementarity-determining regions (CDR; where mutations have a greater chance of being advantageous) and/or decrement of mutability in the framework regions (FR; where mutations are more likely to be lethal) may be accomplished by differential codon usage in concert with the known sequence specificity of the hypermutation mechanism. We have examined 115 nonproductively rearranged human Ig sequences. The mutation patterns in these unexpressed genes are unselected and therefore directly reflect inherent mutation biases. Using a χ2 test, we have shown that the number of mutations in the CDRs is significantly higher than the number of mutations found in the FRs, providing direct evidence for the hypothesis that mutations are preferentially targeted into the CDRs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00006530
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  • 8
    Electronic Resource
    Electronic Resource
    Selenium Bioaccumulation by the Water Boatman Trichocorixa reticulata (Guerin-Meneville) (1999)
    Springer
    Archives of environmental contamination and toxicology 36 (1999), S. 295-300 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract. The input of selenium from subsurface agricultural drainage into surface water systems can result in the accumulation of toxic concentrations of selenium in aquatic food chains. Elevated selenium concentrations in aquatic systems is a significant environmental problem in many areas of the United States. A laboratory investigation was conducted to determine the dominant route of selenium bioaccumulation by the corixid Trichocorixa reticulata, an important food chain organism. The roles of waterborne and foodborne exposure in selenium bioaccumulation were examined using 48-h bioassays. Waterborne selenium concentrations ranged from 0 to 1,000 μg Se/L as selenate. A mixture of two species of blue-green algae cultured in media with selenium concentrations ranging from 0 to 1,000 μg Se/L as selenate was used as a corixid diet in the foodborne treatments. Corixids exposed to waterborne selenate did not accumulate selenium above control concentrations. Corixids fed algae exposed to ≥100 μg Se/L as selenate had significantly higher selenium concentrations than control organisms. These data suggest that corixids may be effectively isolated from the water and selenium accumulation is solely through dietary exposure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002449900474
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  • 9
    Electronic Resource
    Electronic Resource
    The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP (1999)
    [s.l.] : Nature America Inc.
    Nature structural biology 6 (1999), S. 594-601 
    Details
    ISSN: 1072-8368
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The acyl-coenzyme A-binding proteins (ACBPs) contain 26 highly conserved sequence positions. The majority of these have been mutated in the bovine protein, and their influence on the rate of two-state folding and unfolding has been measured. The results identify eight sequence positions, out of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/9384
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  • 10
    Electronic Resource
    Electronic Resource
    15N CP/MAS NMR as an instrument in structure investigations of organosilicon polymers (1999)
    Springer
    Fresenius' journal of analytical chemistry 363 (1999), S. 185-188 
    Details
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract 15N solid state NMR without enrichment is rarely used because of the low sensitivity and low natural abundance of this nucleus. As demonstrated on different nitrogen-containing polysilanes and polysilazanes, it can be shown that with the CP/MAS technique spectra can be obtained in good quality and within acceptable measuring time. Three main different nitrogen sites – NSi3, NSi2H and NSiH2– can be observed as well as changes in the intensities of these sites with reaction and tempering conditions. Thus the spectra give valuable additional information for a better understanding of the structures and their changes within the investigated systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002160051168
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