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  • Cell & Developmental Biology  (282)
  • ASTRONOMY  (198)
  • Biochemistry and Biotechnology  (147)
  • 1985-1989  (623)
  • 1970-1974
  • 1960-1964
  • 1935-1939  (4)
  • 1905-1909
  • 1989  (214)
  • 1988  (228)
  • 1985  (181)
  • 1938  (4)
  • 1898
Collection
Keywords
Publisher
Years
  • 1985-1989  (623)
  • 1970-1974
  • 1960-1964
  • 1935-1939  (4)
  • 1905-1909
    • +
Year
  • 1
    Electronic Resource
    Electronic Resource
    Laboratory studies on the suitability of a fertilizer-tap water medium for mass culture of algae (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 27 (1985), S. 1572-1576 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260271108
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Enhanced sedimentation of mammalian cells following acoustic aggregation (1989)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 34 (1989), S. 559-562 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260340415
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  • 3
    Electronic Resource
    Electronic Resource
    Pharmacological profile of the substituted beta-lactam L-659,286: A member of a new class of human PMN elastase inhibitors (1989)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 39 (1989), S. 47-53 
    Details
    ISSN: 0730-2312
    Keywords: elastase inhibitors ; β-lactams ; lung damage ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Human polymorphonuclear leukocyte elastase (PMN elastase) is inhibited by L-659, 286 (7α-methoxy-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triaz-in-3-yl)thio]methyl]-5-thia-1-aza-6R-bicyclo [4.2.O]oct-2-ene-2-pyrrolidine carboxamide-5,-dioxide) with a Ki of 0.4 μM. This inhibition is time-dependent, rapid, and only slowly reversible, with a t1/2 of 〉 3 days at 25°C. L-659, 286 is also highly selective for PMN elastase, as it does not inhibit thrombin, trypsin, papain, plasmin, chymotrypsin, or cathepsin G. L-659, 286 administered intratracheally inhibits lung damage caused by administration via the same route of human PMN elastase into hamsters. In marmosets, L-659, 286 is cleared from blood very rapidly after an intravenous injection but is recovered in bronchoalveolar lavage fluid for several hours after intratracheal administration.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240390106
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  • 4
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    Fast spectroscopic variations on rapidly-rotating, cool dwarfs. 3: Masses of circumstellar absorbing clouds on AB Doradus (1989)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: New time-resolved H alpha, Ca II H and K and Mg II h and k spectra of the rapidly-rotating K0 dwarf star AB Doradus (= HD 36705). The transient absorption features seen in the H alpha line are also present in the Ca II and Mg II resonance lines. New techniques are developed for measuring the average strength of the line absorption along lines of sight intersecting the cloud. These techniques also give a measure of the projected cloud area. The strength of the resonance line absorption provides useful new constraints on the column densities, projected surface areas, temperatures and internal turbulent velocity dispersions of the circumstellar clouds producing the absorption features. At any given time the star appears to be surrounded by at least 6 to 10 clouds with masses in the range 2 to 6 x 10(exp 17) g. The clouds appear to have turbulent internal velocity dispersions of order 3 to 20 km/s, comparable with the random velocities of discrete filamentary structures in solar quiescent prominences. Night-to-night changes in the amount of Ca II resonance line absorption can be explained by changes in the amplitude of turbulent motions in the clouds. The corresponding changes in the total energy of the internal motions are of order 10(exp 29) erg per cloud. Changes of this magnitude could easily be activated by the frequent energetic (approximately 10(exp 34) erg) x ray flares seen on this star.
    Keywords: ASTRONOMY
    Type: NASA-CR-186563 , NAS 1.26:186563
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 5
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    The project EGRET (Energetic Gamma-Ray Experiment Telescope) on NASA's Gamma-Ray Observatory (GRO) (1988)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: The design, predicted performance, and scientific objectives of the 20-30,000-MeV gamma-ray telescope EGRET for the NASA GRO spacecraft (scheduled for Space Shuttle launch to a 450-km 28.5-deg orbit in 1990) are reviewed. The other GRO instruments are briefly characterized, including the burst and transient-source experiment, the oriented scintillation spectrometer, and the imaging Compton telescope. EGRET comprises an anticoincidence system, a spark chamber, a triggering telescope, an NaI total-absorption spectrometer, a gas supply capable of refilling the chamber four times, and support electronics. EGRET will operate with energy resolution about 15 percent, effective area about 2000 sq cm, sensitivity about 5 x 10 to the -8th/sq cm sec, angular resolution 0.1-0.4 deg, and FOV about 40 deg FWHM. Observations of Galactic point sources, Galactic and extragalactic diffuse emission, gamma-ray bursts, and solar flares are planned.
    Keywords: ASTRONOMY
    Type: Space Science Reviews (ISSN 0038-6308); 49; 1-2,
    Format: text
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    NASA TECHNICAL REPORTS
  • 6
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    A VLBI survey at 2.29 GHz (1985)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: VLBI observations at 2.29 GHz with fringe spacings of about 3 milliarcsec have been performed on 1398 radio sources spread over the entire sky. 917 sources were detected, including 93 percent of the identified BL Lacertae objects, 86 percent of the quasars, and 36 percent of the galaxies. The resulting catalog of compact radio sources is useful for various astrophysical studies and in the formation of VLBI celestial reference frames.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 90; 1599-164
    Format: text
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    NASA TECHNICAL REPORTS
  • 7
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    Arcsecond positions for milliarcsecond VLBI nuclei of extragalactic radio sources. III - 74 sources (1985)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: VLBI measurements at 2290 and 8420 MHz on baselines of 10,000 km have been used to determine the positions of the milliarcsecond nuclei in 74 extragalactic radio sources. Estimated accuracies range from 0.1 to 4.3 arcsec in both right ascension and declination with typical accuracies of about 0.3 arcsec. The observed sources are part of an all-sky VLBI catalog of milliarcsecond radio sources. Arcsecond positions have been determined for 819 sources. These positions are presently being used to identify optical counterparts in the southern hemisphere.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 90; 590-594
    Format: text
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    NASA TECHNICAL REPORTS
  • 8
    Electronic Resource
    Electronic Resource
    Use of cell affinity chromatography for separation of lymphocyte subpopulations (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 27 (1985), S. 603-612 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: We describe the use of affinity chromatography for separation of cell populations that do not differ significantly with respect to gross physical properties such as size, density, or charge. Cell affinity chromatography exploits differences in cell surface macromolecules by passage of mixtures of cell populations through a column containing beads to which are attached chemical ligands with specific binding affinity for particular cell surface receptors. In this article we focus on the application of this concept to separation of mature T lymphocytes from peripheral blood. This serves as a model for the separation of these cells from bone marrow in order to prevent graft-vs.-host disease in bone marrow transplantation. However, the concept of cell affinity chromatography should find more general widespread utility in a variety of biotechnological applications. Thus, we introduce a simple theoretical framework which is necessary in order to understand the results that might be expected in any given situation. Finally, we use this theory to provide a tentative explanation for experimental observation of the effects of temperature and flowrate on the degree of separation achieved for our current pplication.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260270509
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  • 9
    Electronic Resource
    Electronic Resource
    Fundamental studies of glucose oxidase immobilization on controlled pore glass (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 27 (1985), S. 842-851 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Immobilization experiments have been performed with glucose oxidase as enzyme and controlled-pore glass of different pore sizes as support for chemical coupling. The experimental results have been analyzed for comparison with the theoretical model predictions. Analysis of the initial stage of the process gives the fundamental characteristic of the immobilization reaction. These investigations allow us to study the influence of the degree of diffusional restriction on the evolution of the immobilization process and spatial distribution of immobilized enzyme. Nonuniformly distributed concentrations have been achieved within the porous matrix, and suggestions have been made in designing such profiles by choosing appropriate experimental parameters.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260270614
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  • 10
    Electronic Resource
    Electronic Resource
    Modeling of enzyme immobilization in porous membranes (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 27 (1985), S. 1126-1135 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article deals with the mathematical modeling of the process of enzyme immobilization in porous membranes. During the initial period, an analytical solution is available to extract the rate constant for immobilization. Beyond this period, the model equations are solved numerically to yield the transient response of the enzyme concentration in the immobilizing solution and also the evolution of the enzyme loading profile inside the membrane. It is found that the immobilization practically ceases even through the attachment sites are still available within the membrane.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260270807
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