Publication Date:
2014-12-24
Description:
The plant cell wall is an important factor for determining cell shape, function and response to the environment. Secondary cell walls, such as those found in xylem, are composed of cellulose, hemicelluloses and lignin and account for the bulk of plant biomass. The coordination between transcriptional regulation of synthesis for each polymer is complex and vital to cell function. A regulatory hierarchy of developmental switches has been proposed, although the full complement of regulators remains unknown. Here we present a protein-DNA network between Arabidopsis thaliana transcription factors and secondary cell wall metabolic genes with gene expression regulated by a series of feed-forward loops. This model allowed us to develop and validate new hypotheses about secondary wall gene regulation under abiotic stress. Distinct stresses are able to perturb targeted genes to potentially promote functional adaptation. These interactions will serve as a foundation for understanding the regulation of a complex, integral plant component.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333722/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333722/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Taylor-Teeples, M -- Lin, L -- de Lucas, M -- Turco, G -- Toal, T W -- Gaudinier, A -- Young, N F -- Trabucco, G M -- Veling, M T -- Lamothe, R -- Handakumbura, P P -- Xiong, G -- Wang, C -- Corwin, J -- Tsoukalas, A -- Zhang, L -- Ware, D -- Pauly, M -- Kliebenstein, D J -- Dehesh, K -- Tagkopoulos, I -- Breton, G -- Pruneda-Paz, J L -- Ahnert, S E -- Kay, S A -- Hazen, S P -- Brady, S M -- R01 GM056006/GM/NIGMS NIH HHS/ -- R01 GM107311/GM/NIGMS NIH HHS/ -- R01GM056006/GM/NIGMS NIH HHS/ -- R01GM107311/GM/NIGMS NIH HHS/ -- R25 GM056765/GM/NIGMS NIH HHS/ -- RC2 GM092412/GM/NIGMS NIH HHS/ -- RC2GM092412/GM/NIGMS NIH HHS/ -- England -- Nature. 2015 Jan 29;517(7536):571-5. doi: 10.1038/nature14099. Epub 2014 Dec 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉1] Department of Plant Biology, University of California Davis, One Shields Avenue, Davis, California 95616, USA [2] Genome Center, University of California Davis, One Shields Avenue, Davis, California 95616, USA. ; Biology Department, University of Massachusetts, Amherst, Massachusetts 01003, USA. ; Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California 94720, USA. ; Department of Plant Biology, University of California Davis, One Shields Avenue, Davis, California 95616, USA. ; Department of Plant Sciences, University of California Davis, One Shields Avenue, Davis, California 95616, USA. ; 1] Genome Center, University of California Davis, One Shields Avenue, Davis, California 95616, USA [2] Department of Computer Science, University of California Davis, One Shields Avenue, Davis, California 95616, USA. ; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. ; 1] Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA [2] US Department of Agriculture, Agricultural Research Service, Ithaca, New York 14853, USA. ; Section of Cell and Developmental Biology, Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA. ; Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25533953" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/*genetics/growth & development/*metabolism
;
Arabidopsis Proteins/genetics/metabolism
;
Cell Wall/*metabolism
;
DNA, Plant/genetics/metabolism
;
E2F Transcription Factors/metabolism
;
Feedback
;
Gene Expression Regulation, Developmental/genetics
;
Gene Expression Regulation, Plant/*genetics
;
Gene Regulatory Networks/*genetics
;
Iron/deficiency
;
Organ Specificity
;
Promoter Regions, Genetic/genetics
;
Reproducibility of Results
;
Salinity
;
Time Factors
;
Transcription Factors/*metabolism
;
Xylem/genetics/growth & development/metabolism
Print ISSN:
0028-0836
Electronic ISSN:
1476-4687
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
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