Publication Date:
2017-07-18
Description:
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening Nature Communications, Published online: 17 July 2017; doi:10.1038/ncomms16081 Encoded Library Technology (ELT) has streamlined the identification of chemical ligands for protein targets in drug discovery. Here, the authors optimize the ELT approach to screen multiple proteins in parallel and identify promising targets and antibacterial compounds for S. aureus , A. baumannii and M. tuberculosis .
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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