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Description: A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells Cell Death and Disease 4, e547 (March 2013). doi:10.1038/cddis.2013.45 Authors: T C Izidoro-Toledo, A C Borges, D D Araújo, D P S Leitão Mazzi, F O Nascimento, J F Sousa, C P Alves, A P B Paiva, D M Trindade, E V Patussi, P M Peixoto, K W Kinnally & E M Espreafico

Keywords: Myosin-VaDLC1/DLC2apoptosismelanomaBmf

Electronic ISSN: 2041-4889

Topics: Biology , Medicine

Published by Springer Nature

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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax) (2015)

J D Leverson; H Zhang; J Chen; S K Tahir; D C Phillips; J Xue; P Nimmer; S Jin; M Smith; Y Xiao; P Kovar; A Tanaka; M Bruncko; G S Sheppard; L Wang; S Gierke; L Kategaya; D J Anderson; C Wong; J Eastham-Anderson; M J C Ludlam; D Sampath; W J Fairbrother; I Wertz; S H Rosenberg; C Tse; S W Elmore; A J Souers

Springer Nature

In: Cell Death & Disease

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Publication Date: 2015-01-16

Description: Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax) Cell Death and Disease 6, e1590 (January 2015). doi:10.1038/cddis.2014.561 Authors: J D Leverson, H Zhang, J Chen, S K Tahir, D C Phillips, J Xue, P Nimmer, S Jin, M Smith, Y Xiao, P Kovar, A Tanaka, M Bruncko, G S Sheppard, L Wang, S Gierke, L Kategaya, D J Anderson, C Wong, J Eastham-Anderson, M J C Ludlam, D Sampath, W J Fairbrother, I Wertz, S H Rosenberg, C Tse, S W Elmore & A J Souers

Electronic ISSN: 2041-4889

Topics: Biology , Medicine

Published by Springer Nature

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SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α (2015)

D Pastore; D Della-Morte; A Coppola; B Capuani; M F Lombardo; F Pacifici; F Ferrelli; R Arriga; C Mammi; M Federici; A Bellia; N Di Daniele; M Tesauro; G Donadel; D Noto; P Sbraccia; G Sconocchia; D Lauro

Springer Nature

In: Cell Death & Disease

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Publication Date: 2015-09-18

Description: SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α Cell Death and Disease 6, e1890 (September 2015). doi:10.1038/cddis.2015.232 Authors: D Pastore, D Della-Morte, A Coppola, B Capuani, M F Lombardo, F Pacifici, F Ferrelli, R Arriga, C Mammi, M Federici, A Bellia, N Di Daniele, M Tesauro, G Donadel, D Noto, P Sbraccia, G Sconocchia & D Lauro

Electronic ISSN: 2041-4889

Topics: Biology , Medicine

Published by Springer Nature

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Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis (2013)

C Wiel; A Augert; D F Vincent; D Gitenay; D Vindrieux; B Le CalvéV Arfi; H Lallet-Daher; C Reynaud; I Treilleux; L Bartholin; E Lelievre; D Bernard

Springer Nature

In: Cell Death & Disease

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Publication Date: 2013-10-11

Description: Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis Cell Death and Disease 4, e855 (October 2013). doi:10.1038/cddis.2013.382 Authors: C Wiel, A Augert, D F Vincent, D Gitenay, D Vindrieux, B Le Calvé, V Arfi, H Lallet-Daher, C Reynaud, I Treilleux, L Bartholin, E Lelievre & D Bernard

Keywords: senescencelysyl oxidaseoncogenic stressFAK

Electronic ISSN: 2041-4889

Topics: Biology , Medicine

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Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity (2014)

D Schmid; G E Jarvis; F Fay; D M Small; M K Greene; J Majkut; S Spence; K M McLaughlin; K D McCloskey; P G Johnston; A Kissenpfennig; D B Longley; C J Scott

Springer Nature

In: Cell Death & Disease

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Publication Date: 2014-10-10

Description: Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity Cell Death and Disease 5, e1454 (October 2014). doi:10.1038/cddis.2014.413 Authors: D Schmid, G E Jarvis, F Fay, D M Small, M K Greene, J Majkut, S Spence, K M McLaughlin, K D McCloskey, P G Johnston, A Kissenpfennig, D B Longley & C J Scott

Electronic ISSN: 2041-4889

Topics: Biology , Medicine

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Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma (2014)

K E McCabe; K Bacos; D Lu; J R Delaney; J Axelrod; M D Potter; M Vamos; V Wong; N D P Cosford; R Xiang; D G Stupack

Springer Nature

In: Cell Death & Disease

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Publication Date: 2014-10-31

Description: Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma Cell Death and Disease 5, e1496 (October 2014). doi:10.1038/cddis.2014.448 Authors: K E McCabe, K Bacos, D Lu, J R Delaney, J Axelrod, M D Potter, M Vamos, V Wong, N D P Cosford, R Xiang & D G Stupack

Electronic ISSN: 2041-4889

Topics: Biology , Medicine

Published by Springer Nature

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