Publication Date:
2015-07-19
Description:
Article Inhibition of mitochondrial fragmentation can block or delay cell death. Here the authors show that the signalling axis E2F1-miR-421-Pink1 represents a major regulator of mitochondrial fission and cardiomyocyte death, identifying potential therapeutic targets for treatment of heart failure. Nature Communications doi: 10.1038/ncomms8619 Authors: Kun Wang, Lu-Yu Zhou, Jian-Xun Wang, Yin Wang, Teng Sun, Bing Zhao, Yong-Jie Yang, Tao An, Bo Long, Na Li, Cui-Yun Liu, Ying Gong, Jin-Ning Gao, Yan-Han Dong, Jian Zhang, Pei-Feng Li
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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