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Stereotactic Radiosurgery for the Treatment of Central Nervous System Meningiomas (2021)

Longhi, Michele. [editor.] ; Motti, Enrico D. F. [editor.] ; Nicolato, Antonio. [editor.] ; [et al.]

Cham :Springer International Publishing :

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Keywords: Nervous system Surgery. ; Radiology. ; Biophysics. ; Nervous system Radiography. ; Neurology . ; Neurosciences. ; Neurosurgery. ; Radiology. ; Biophysics. ; Neuroradiology. ; Neurology. ; Neuroscience.

Description / Table of Contents: Foreword -- Preface -- Introduction -- 1. Physics and radiation dosage issues in neuroradiosurgical treatment of meningiomas -- 2. Imaging Approaches for radiosurgical treatment of Meningiomas -- 3. MEDICAL MANAGEMENT OF MENINGIOMAS -- 4. Systemic Treatments for Grade II and III Meningiomas (WHO) -- 5. Gamma Knife Radiosurgery for Posterior Cranial Fossa Meningioma -- 6. Stereotactic Radiosurgery for Cavernous Sinus Meningiomas -- 7. Hypofractionated radiosurgery for perioptic meningiomas: Current practice, principles and treatment quandary -- 8. Hypofractionation and normofractionation in Skull Base Meningiomas -- 9. Atypical and anaplastic meningiomas: is there a role for stereotactic radiosurgery? -- 10. CyberKnife Treatment of Atypical Meningiomas (GII) -- 11. SRS & Microsurgery: antagonistic or complementary in the treatment of meningiomas? -- 12. Combined microsurgical and radiosurgical treatment in intracranial meningiomas -- 13. SRS in Incidental Meningioma: Whether to Treat and When -- 14. Side-effects of SRS treatment of low-grade meningioma: types, frequency and management -- 15. Single- and Multiple-Session Radiosurgery for Spinal Meningioma: Radiosurgery for spinal meningioma -- 16. Guidelines and evidence-based recommendations for the radiosurgical treatment of CNS meningiomas.

Abstract: Meningiomas are the most frequently reported neuro-oncologic condition, accounting for 12% to 30% of all primary intracranial tumors. The first case of intracranial meningioma treated with stereotactic radiosurgery was reported by Backlund E-O in 1971. Since then, more than 200,000 meningiomas have been treated with stereotactic radiosurgery worldwide to date. The large number of patients treated using this method is due to the fact that meningiomas are frequently located in critical areas and microsurgery is often associated with severe and permanent neurological complications. This book discusses the advantages, risks and limits of stereotactic radiosurgery relating to all regions of interest for a neuroradiosurgical approach for the treatment of central nervous system meningiomas. Firstly, it presents an introduction focusing on the “state of the art”. It then discusses the physics, imaging, neurological and neuro-oncological issues in multidisciplinary management. Lastly, it features a summary of results, including the most recent published papers regarding all the locations involved in the stereotactic radiosurgery treatment as well as new approaches to meningiomas, with particular reference to the hypofrationated treatments. Intended for anyone involved in the neuroradiosurgical treatment of brain diseases, the book provides an up-to-date overview of the latest stereotactic radiosurgery treatment of central nervous system meningiomas.

Type of Medium: Online Resource

Pages: X, 160 p. 30 illus., 25 illus. in color. , online resource.

Edition: 1st ed. 2021.

ISBN: 9783030794194

URL: https://doi.org/10.1007/978-3-030-79419-4

DOI: 10.1007/978-3-030-79419-4

DDC: 617.48

Language: English

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Biomarkers of Radiation in the Environment : Robust Tools for Risk Assessment (2022)

Wood, Michael D. [editor.] ; Mothersill, Carmel E. [editor.] ; Tsakanova, Gohar. [editor.] ; [et al.]

Dordrecht :Springer Netherlands :

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Keywords: Biochemical markers. ; Radiation dosimetry. ; Environmental chemistry. ; Biochemistry. ; Biomarkers. ; Radiation Dosimetry and Protection . ; Environmental Chemistry. ; Biological Chemistry.

Description / Table of Contents: TECHNIQUES FOR BIOMARKER DEVELOPMENT -- Chapter 1. Reducing Uncertainties In Live Monitoring Of Radiation In Wildlife -- Chapter 2. Synchrotron Light Facilities And Applications In Life Sciences -- Chapter 3. Elemental Imaging In Biology Using Synchrotron X-Ray Fluorescence Microscopy -- LOW-DOSE EFFECT MECHANISMS Chapter 4. Modelling Direct And Indirect Effects Of Radiation: Experimental, Clinical And Environmental Implications -- Chapter 5. Immune Networks In The Context Of Low Dose Ionizing Radiation -- Chapter 6. Learning From Nato Biomarker Research For Humans -- BIOMARKERS FOR RISK EVALUATION -- Chapter 7. Exosomes As Radiation Biomarkers -- Chapter 8. Monitoring Very Low Dose Radiation Damage In Dna Using “Field-Friendly” Biomarkers -- Chapter 9. The Development Of Bio-Assays Based On Non-Targeted Effects Of Radiation; A Potential Worm-Hole Into Ecosystem Level Biomarkers -- BIOMARKERS IN WILDLIFE Chapter 10. Birds As Bioindicators Of Radioactive Contamination And Its Effects -- Chapter 11. Amphibians In Field Radioecology: A Review And Perspective -- Chapter 12. Measuring Adaptive Responses Following Chronic And Low Dose Exposure In Amphibians -- Chapter 13. Are There Ecosystem-Relevant Endpoints For Measuring Radiation Impacts?.-Chapter 14. Biomarkers And Ecological Indicators For Environmental Radioactivity In Invertebrates.-BIOMARKER USE AND RESPONSES -- Environment, Workers And Public -- Chapter 16. Application Of The International System Of Radiation Protection In Fit-For-Purpose Assessment Of Impacts -- Chapter 17. Practicalities Of Mainstreaming Biomarker Use – A Canadian Perspective -- Index.

Abstract: This proceedings volume results from the NATO Advanced Research Workshop on 'Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment (BRITE)’. The BRITE workshop discussed insights from cancer research, epigenetics, non-human and human risk assessment, since many of the state-of-the-art biomarkers being developed for humans deserve consideration for environmental applications and vice versa. Sessions were very wide-ranging covering methods, mechanisms, cross disciplinary application and regulation. The chapters in this book have been grouped into five major themes that were covered by the BRITE workshop: · Techniques for biomarker development · Low-dose effect mechanisms · Biomarkers for risk evaluation · Biomarkers in wildlife · Biomarker use and responses Each chapter has been written independently and reflects the views of the chapter author(s). Therefore, the readers can form their own balanced view of the different perspectives on biomarkers of radiation in the environment. Given the breadth of topics covered and the state-of-the-art perspectives shared by leading experts in their respective fields, this book should form a valuable resource for anyone with an interest in how biomarkers can be used to improve our understanding of radiation in the environment and its potential impacts.

Type of Medium: Online Resource

Pages: XVI, 330 p. 1 illus. , online resource.

Edition: 1st ed. 2022.

ISBN: 9789402421019

Series Statement: NATO Science for Peace and Security Series A: Chemistry and Biology,

URL: https://doi.org/10.1007/978-94-024-2101-9

DOI: 10.1007/978-94-024-2101-9

DDC: 610.72

Language: English

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Design of Experiments and Advanced Statistical Techniques in Clinical Research (2020)

D. M., Basavarajaiah. ; Narasimha Murthy, Bhamidipati.

Singapore :Springer Nature Singapore :

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Keywords: Medicine Research. ; Biology Research. ; Statistics . ; Biometry. ; Biomedical Research. ; Applied Statistics. ; Biostatistics.

Description / Table of Contents: Design of Clinical Research and its Practical Approach -- Advanced Design of Experiment Approach to Clinical and Medical Research -- Random Forest and Concept of Decision Tree Model -- Application of Machine Learning in Medical Research -- Statistical Genetic and its Application in Drug Trail -- Statistical Implications for Estimation of Genetic Traits in Human Vaccine Trail -- Statistical Implications and its Practical Approach to Research Methodology -- Statistical Models Approach to Life Threatened Diseases -- Meta Analysis in Clinical and Life Science Research -- Pharmokinitic and Statistical Modelling -- Imputation Methods Approach to Clinical and Life Science Research Data Sets -- Ethical Perspective of Medical Research.

Abstract: Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in clinical situations and ways to assess the stability of these models and other quantitative conclusions drawn by realistic experimental data sets. Design of experiments and recent posthoc tests have been used in comparing treatment effects and precision of the experimentation. This book also facilitates clinicians towards understanding statistics and enabling them to follow and evaluate the real empirical studies (formulation of randomized control trial) that pledge insight evidence base for clinical practices. This book will be a useful resource for clinicians, postgraduates scholars in medicines, clinical research beginners and academicians to nurture high-level statistical tools with extensive scope.

Type of Medium: Online Resource

Pages: XXXV, 356 p. 190 illus., 133 illus. in color. , online resource.

Edition: 1st ed. 2020.

ISBN: 9789811582103

URL: https://doi.org/10.1007/978-981-15-8210-3

DOI: 10.1007/978-981-15-8210-3

DDC: 610.72

Language: English

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Pineal Neurosurgery (2020)

Hoz, Samer S. [editor.] ; Dolachee, Ali A. [editor.] ; Salih, Hayder R. [editor.] ; [et al.]

Cham :Springer International Publishing :

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Keywords: Nervous system Surgery. ; Neurology . ; Neurosciences. ; Neurosurgery. ; Neurology. ; Neuroscience.

Description / Table of Contents: Chapter 1 Embryology of the Pineal Gland -- Chapter 2 Anatomy of the Pineal Gland -- Chapter 3 Physiology of the Pineal Gland -- Chapter 4 Neuroimaging of the Pineal Gland -- Chapter 5 Tumors of the Pineal Gland -- Chapter 6 Non-tumorous Lesions of the Pineal Gland -- Chapter 7 Treatment and Approaches for the Pineal Gland Region -- Chapter 8 Interesting Cases of Pineal Gland Diseases and Surgery -- Chapter 9 Animal Based Surgical Training in Pineal Approaches -- Chapter 10 Evolutionary Retrace of the Third Eye.

Abstract: This comprehensive book focuses on neurosurgical aspects of the pineal gland. By covering virtually all aspects of the pineal gland, it fills an important gap in the neurosurgical literature. Further, it approaches this vital component of the human brain from various angles: embryology, anatomy, physiology, pathology, radiology and surgical techniques. More than 70 single-best-answer multiple-choice questions (MCQs) are distributed throughout the chapters. Offering an essential review for residents and surgeons across neurosurgical disciplines and containing most of the critical information needed to prepare for both the primary and certification exam, the book will also be of interest to neurologists, neuroscientists and medical students. .

Type of Medium: Online Resource

Pages: XXVIII, 141 p. 42 illus., 36 illus. in color. , online resource.

Edition: 1st ed. 2020.

ISBN: 9783030531911

URL: https://doi.org/10.1007/978-3-030-53191-1

DOI: 10.1007/978-3-030-53191-1

DDC: 617.48

Language: English

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