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  • 1
    Keywords: Virology. ; Medicine Research. ; Biology Research. ; Life sciences. ; Virology. ; Biomedical Research. ; Life Sciences.
    Description / Table of Contents: 1. The Quest for Excellence and the Challenge of Gender Equality in Arbovirology: A Celebration of Women’s Contributions to the Field -- 2. Serendipity and Arboviruses -- 3. The Tapestry of Life: Weaving an Arbovirologist -- 4. Arbovirus and Viral Hemorrhagic Fevers Research Inception in Central and West Africa -- 5. From Bwamba to the Present: The Changing Forest of Arbovirology -- 6. Fighting Dengue, Chikungunya and Japanese Encephalitis -- 7. Chronicles of Hantaviruses: Foundations of Epidemiology and Ecology -- 8. Yellow Fever and Other Viruses in West Africa -- 9. The “Golden Age” of Arbovirology, 1950-1969 -- 10. Twenty-Seven Years of Field Studies on Dengue and Aedes Aegypti in Latin America -- 11. 50 Years of Medical Entomology: Miscellaneous Interesting Findings -- 12. Remembrances of Virology Past -- 13. An Overview of Arbovirology in São Paulo State, Southeastern Brazil: Highlighting the Virus Research Center in Ribeirão Preto City -- 14. An Unplanned Career in Arbovirology.
    Abstract: These books bring together a panel of expert arbovirologists who recall the history of arbovirology from very personal perspectives. In these timely volumes, the authors describe seminal moments in their experiences in the field and how they integrated these findings with lab studies to further clarify the ecology and epidemiology of diverse arboviruses. Authors identify the most pressing questions that remain to be answered, providing a basis for current research and a stimulus to engage those entering the field. Over the last 20 years a generational gap has developed between the giants of arbovirus research and discovery and the new generation. This gap developed due to an ebbing of training and investment in passing the scepter to the next generation, leading to a lack of continuity among the generations that threatens to derail the rich history of virus discovery, field epidemiology and understanding of the richness of diversity that surrounds us. This lack of continuity may have immediate and disastrous consequences for public health when yet to be discovered arboviruses emerge. The purpose of these books is to bridge this gap by providing a historical context for the work being done today and provide continuity between the generations. To this end, the books provide a narrative of the thrill of scientific discovery and excitement of field adventures and lab studies of that generation -- essential reading for every arbovirologist, and highly recommended for all virologists and public health officials, as well as those students considering future research options. Volume I consists of the personal reflections of arbovirologists who played a significant role in the advancement of arbovirology across the globe. Volume II transitions to descriptions of region-specific and virus family-specific perspectives of arbovirology, as well as recollections of the early events of molecular advances and pathogenesis studies.
    Type of Medium: Online Resource
    Pages: XX, 542 p. 258 illus., 200 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031219993
    DDC: 579.2
    Language: English
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  • 2
    Keywords: Virology. ; Medicine Research. ; Biology Research. ; Virology. ; Biomedical Research.
    Description / Table of Contents: 1. RNAi: The Mosquito Defense System Against Damage Due to Arbovirus Infection -- 2. A First-hand Account of the Progression of Flavivirus Molecular Biology -- 3. Sindbis Virus: Studies of Alphavirus Pathogenesis -- 4. Mechanisms of Tick-borne Virus Transmission -- 5. The Use of Humanized Mice to Understand Arbovirus Pathogenesis -- 6. Molecular Biology of Arboviruses -- 7. Mosquito-Virus-Environment Interactions -- 8. A Brief Historical Overview of the Discovery of Arboviruses in the USSR and Russia -- 9. The History of the Emergence of La Crosse Encephalitis Virus in the Driftless Area of the United States: A Mosquito Runs Through It! -- 10. “It Isn’t Going to Reach Here”: Venezuelan Equine Encephalitis in Texas, 1971 -- 11. History of Arbovirology in Canada -- 12. Arbovirus Discovery in the British Empire: India and Africa, c. 1880-1960 -- 13. History of Arbovirology in Japan -- 14. Ockelbo Disease in Sweden: Unraveling the Epidemiology, Ecology, and Evolution of Sindbis Virus -- 15. Human Arboviruses in Eastern, South-Eastern, and Southern Asia: A Brief History of Their Isolation and Characteristics -- 16. History of Arbovirus Research in Kenya -- 17. Vector Studies in the Amazon Basin Region of Peru -- 18. Zika Virus Studies in West Africa -- 19. Hemorrhagic Fevers -- 20. Chronicles of Hantaviruses: Virus Discovery to Vaccine Candidates -- 21. A History of Tick-Borne Encephalitis and Its Virus -- 22. Kyasanur Forest Disease -- 23. The Discovery of Insect-Specific Viruses in Australia: Mossies, Old Mates, and New Methods.
    Abstract: These books bring together a panel of expert arbovirologists who recall the history of arbovirology from very personal perspectives. In these timely volumes, the authors describe seminal moments in their experiences in the field and how they integrated these findings with lab studies to further clarify the ecology and epidemiology of diverse arboviruses. Authors identify the most pressing questions that remain to be answered, providing a basis for current research and a stimulus to engage those entering the field. Over the last 20 years a generational gap has developed between the giants of arbovirus research and discovery and the new generation. This gap developed due to an ebbing of training and investment in passing the scepter to the next generation, leading to a lack of continuity among the generations that threatens to derail the rich history of virus discovery, field epidemiology and understanding of the richness of diversity that surrounds us. This lack of continuity may have immediate and disastrous consequences for public health when yet to be discovered arboviruses emerge. The purpose of these books is to bridge this gap by providing a historical context for the work being done today and provide continuity between the generations. To this end, the books provide a narrative of the thrill of scientific discovery and excitement of field adventures and lab studies of that generation -- essential reading for every arbovirologist, and highly recommended for all virologists and public health officials, as well as those students considering future research options. Volume I consists of the personal reflections of arbovirologists who played a significant role in the advancement of arbovirology across the globe. Volume II transitions to descriptions of region-specific and virus family-specific perspectives of arbovirology, as well as recollections of the early events of molecular advances and pathogenesis studies.
    Type of Medium: Online Resource
    Pages: XX, 530 p. 171 illus., 121 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031220036
    DDC: 579.2
    Language: English
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  • 3
    Keywords: Biochemical markers. ; Radiation dosimetry. ; Environmental chemistry. ; Biochemistry. ; Biomarkers. ; Radiation Dosimetry and Protection . ; Environmental Chemistry. ; Biological Chemistry.
    Description / Table of Contents: TECHNIQUES FOR BIOMARKER DEVELOPMENT -- Chapter 1. Reducing Uncertainties In Live Monitoring Of Radiation In Wildlife -- Chapter 2. Synchrotron Light Facilities And Applications In Life Sciences -- Chapter 3. Elemental Imaging In Biology Using Synchrotron X-Ray Fluorescence Microscopy -- LOW-DOSE EFFECT MECHANISMS Chapter 4. Modelling Direct And Indirect Effects Of Radiation: Experimental, Clinical And Environmental Implications -- Chapter 5. Immune Networks In The Context Of Low Dose Ionizing Radiation -- Chapter 6. Learning From Nato Biomarker Research For Humans -- BIOMARKERS FOR RISK EVALUATION -- Chapter 7. Exosomes As Radiation Biomarkers -- Chapter 8. Monitoring Very Low Dose Radiation Damage In Dna Using “Field-Friendly” Biomarkers -- Chapter 9. The Development Of Bio-Assays Based On Non-Targeted Effects Of Radiation; A Potential Worm-Hole Into Ecosystem Level Biomarkers -- BIOMARKERS IN WILDLIFE Chapter 10. Birds As Bioindicators Of Radioactive Contamination And Its Effects -- Chapter 11. Amphibians In Field Radioecology: A Review And Perspective -- Chapter 12. Measuring Adaptive Responses Following Chronic And Low Dose Exposure In Amphibians -- Chapter 13. Are There Ecosystem-Relevant Endpoints For Measuring Radiation Impacts?.-Chapter 14. Biomarkers And Ecological Indicators For Environmental Radioactivity In Invertebrates.-BIOMARKER USE AND RESPONSES -- Environment, Workers And Public -- Chapter 16. Application Of The International System Of Radiation Protection In Fit-For-Purpose Assessment Of Impacts -- Chapter 17. Practicalities Of Mainstreaming Biomarker Use – A Canadian Perspective -- Index.
    Abstract: This proceedings volume results from the NATO Advanced Research Workshop on 'Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment (BRITE)’. The BRITE workshop discussed insights from cancer research, epigenetics, non-human and human risk assessment, since many of the state-of-the-art biomarkers being developed for humans deserve consideration for environmental applications and vice versa. Sessions were very wide-ranging covering methods, mechanisms, cross disciplinary application and regulation. The chapters in this book have been grouped into five major themes that were covered by the BRITE workshop: · Techniques for biomarker development · Low-dose effect mechanisms · Biomarkers for risk evaluation · Biomarkers in wildlife · Biomarker use and responses Each chapter has been written independently and reflects the views of the chapter author(s). Therefore, the readers can form their own balanced view of the different perspectives on biomarkers of radiation in the environment. Given the breadth of topics covered and the state-of-the-art perspectives shared by leading experts in their respective fields, this book should form a valuable resource for anyone with an interest in how biomarkers can be used to improve our understanding of radiation in the environment and its potential impacts.
    Type of Medium: Online Resource
    Pages: XVI, 330 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789402421019
    Series Statement: NATO Science for Peace and Security Series A: Chemistry and Biology,
    DDC: 610.72
    Language: English
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  • 4
    Keywords: Medicine Research. ; Biology Research. ; Statistics . ; Biometry. ; Biomedical Research. ; Applied Statistics. ; Biostatistics.
    Description / Table of Contents: Design of Clinical Research and its Practical Approach -- Advanced Design of Experiment Approach to Clinical and Medical Research -- Random Forest and Concept of Decision Tree Model -- Application of Machine Learning in Medical Research -- Statistical Genetic and its Application in Drug Trail -- Statistical Implications for Estimation of Genetic Traits in Human Vaccine Trail -- Statistical Implications and its Practical Approach to Research Methodology -- Statistical Models Approach to Life Threatened Diseases -- Meta Analysis in Clinical and Life Science Research -- Pharmokinitic and Statistical Modelling -- Imputation Methods Approach to Clinical and Life Science Research Data Sets -- Ethical Perspective of Medical Research.
    Abstract: Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in clinical situations and ways to assess the stability of these models and other quantitative conclusions drawn by realistic experimental data sets. Design of experiments and recent posthoc tests have been used in comparing treatment effects and precision of the experimentation. This book also facilitates clinicians towards understanding statistics and enabling them to follow and evaluate the real empirical studies (formulation of randomized control trial) that pledge insight evidence base for clinical practices. This book will be a useful resource for clinicians, postgraduates scholars in medicines, clinical research beginners and academicians to nurture high-level statistical tools with extensive scope.
    Type of Medium: Online Resource
    Pages: XXXV, 356 p. 190 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811582103
    DDC: 610.72
    Language: English
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