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  • Books  (2)
  • Cham :Springer International Publishing :  (2)
  • Berlin ; Heidelberg : Springer
  • Cambridge [u.a.] : Cambridge Univ. Press
  • Washington, DC : United States Gov. Print. Off.
  • 571.878  (2)
Collection
  • Books  (2)
Publisher
  • Cham :Springer International Publishing :  (2)
  • Berlin ; Heidelberg : Springer
  • Cambridge [u.a.] : Cambridge Univ. Press
  • Washington, DC : United States Gov. Print. Off.
Language
Years
DDC
  • 1
    Keywords: Aging. ; Cytology. ; Clinical biochemistry. ; Proteins . ; Ageing. ; Cell Biology. ; Medical Biochemistry. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1:Introduction: Historical Development and Progression of Clinical Research on Ageing -- Chapter 2:Bone Cells Metabolic Changes Induced by Ageing -- Chapter 3:Chronic Inflammation as an Underlying Mechanism of Ageing and Ageing-related Diseases -- Chapter 4: Heart Disease and Ageing: The roles of Senescence, Mitochondria and Telomerase in Cardiovascular Disease -- Chapter 5: Chronic Kidney Disease and the Exposome of Ageing -- Chapter 6: Sarcopenia and Ageing -- Chapter 7: Tendon Ageing -- Chapter 8: Virus Infections in Older People -- Chapter 9: Models and Biomarkers for Ovarian Ageing -- Chapter 10: Ageing and the Autonomic Nervous System -- Chapter 11: Astrocytes in Ageing -- Chapter 12: Hearing and Ageing -- Chapter 13: Melatonin and Ageing -- Chapter 14: Protein and Energy Supplements for the Elderly -- Chapter 15: Ageing, Metabolic Dysfunction, and the Therapeutic Role of Antioxidants -- Chapter 16: Clinical Ageing.
    Abstract: This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice. To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute to ageing events and how various organs and tissues (e.g. tendons, ears, heart muscle, and the endocrine system) age. This book follows on from Parts I, II and III of Biochemistry and Cell Biology of Ageing within the Subcellular Biochemistry book series and aims to bring the subcellular and clinical areas into closer contact by including interesting and significant biomedical ageing topics that were not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
    Type of Medium: Online Resource
    Pages: VIII, 458 p. 48 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031265761
    Series Statement: Subcellular Biochemistry, 103
    DDC: 571.878
    Language: English
    Location Call Number Expected Availability
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  • 2
    Keywords: Aging. ; Cytology. ; Clinical biochemistry. ; Proteins . ; Ageing. ; Cell Biology. ; Medical Biochemistry. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1: Introduction: Progression of the Science of Ageing -- Chapter 2: Chromatin structure from development to ageing -- Chapter 3: The nuclear envelope in ageing and progeria -- Chapter 4: Mitochondrial DNA mutations and ageing -- Chapter 5: The Proteasome and Ageing -- Chapter 6: Gap junctions and Ageing -- Chapter 7: Cellular senescence and ageing -- Chapter 8: Therapeutic opportunities presented by modulation of cellular senescence -- Chapter 9: Ageing at Molecular Level: Role of MicroRNAs -- Chapter 10: CircRNAandAgeing -- Chapter 11: Extracellular vesicles and cellular ageing -- Chapter 12: Fibrinogen, Coagulation and Ageing -- Chapter 13: An Insight intoPlateletsat Older Age:Cellular and Clinical Perspectives -- Chapter 14: Ageing skeletal muscle: The ubiquitous muscle stem cell -- Chapter 15: Age-related changes in central nervous system 5-hydroxytryptamine signalling and its potential effects on the regulation of lifespan -- Chapter 16: Systems Biology of Ageing.
    Abstract: This, our third book on the Biochemistry and Cell Biology of Ageing in the Subcellular Biochemistry series, expands on the content of Part I, by covering additional biomedical topics. The 16 chapters included here, contributed by international knowledgeable scientists, review these further interesting topics at an advanced level. Following an Introductory chapter, these topics are included: Chromatin Structure from Development to Ageing, the Nuclear Envelope in Ageing and Progeria, Mitochondrial DNA Mutations and Ageing, the Proteasome and Ageing, Gap Junctions and Ageing, Cellular Senescence and Ageing, Therapeutic Opportunities Presented by Modulation of Cellular Senescence, Ageing at Molecular Level: Role of MicroRNAs, CircRNA and Ageing, Extracellular Vesicles and Cellular Ageing,Fibrinogen, Coagulation and Ageing, An Insight into Platelets at Older Age: Cellular and Clinical Perspectives, Ageing Skeletal Muscle: The Ubiquitous Muscle Stem Cell, Age-related Changes in Central Nervous System 5-Hydroxytryptamine Signalling and its Potential effects on the Regulation of Lifespan, and Systems Biology of Ageing. The book is primarily directed to advanced biomedical science and medical students, postgraduates, researchers and academics in the field of Ageing. A further companion volume of the series (Part IV) covering the more Clinical Science aspects will be published soon. The seemingly endless expansion of ageing research continues to throw up important areas, that may well be covered in future volumes, together with updates of rapidly moving subjects. Thus, a further book on Anti-ageing Interventions (Part V) is under production.
    Type of Medium: Online Resource
    Pages: IX, 424 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031214103
    Series Statement: Subcellular Biochemistry, 102
    DDC: 571.878
    Language: English
    Location Call Number Expected Availability
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