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  • Books  (4)
  • Pharmaceutical chemistry.  (2)
  • Sustainability.  (2)
  • 551.48  (2)
  • 615  (2)
  • 1
    Online Resource
    Online Resource
    Macrophage Targeted Delivery Systems : Basic Concepts and Therapeutic Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Cytology. ; Toxicology. ; Immunology. ; Pharmacology. ; Pharmaceutics. ; Cell Biology. ; Toxicology. ; Immunology.
    Description / Table of Contents: Part I Anatomy, Physiology and Pharmacology of Macrophages -- Introduction to Anatomy and Physiology of Macrophages from Drug Delivery Perspective -- Introduction to Pharmacology of Macrophages from Drug Delivery Perspective -- Mechanisms and Ways of Macrophage Delivery -- Macrophage Associated Disorders: Pathophysiology, Treatment Challenges and Possible Solutions -- Understanding Macrophage Associated Diseases and Applications of Nano Drug Delivery Systems -- Part II Polymeric Nanoparticles for Macrophage Targeting -- Targeting of Macrophages: Basic and therapeutic Role of Polymeric Nanoparticles -- Polymeric Nanoparticles Based Drug and Gene Delivery to Macrophages -- Surface Modification of Nanoparticles for Macrophage Targeting -- Part III Lipid Nanoparticles for Macrophage Targeting -- Liposomes as Delivery System for Macrophage Targeting -- Solid Lipid Nanoparticles Based Drug and Gene Delivery to Macrophages -- In vivo Fate of Colloidal Carriers Undergoing Macrophage Targeting -- Nanoparticle-based Theranostics for Macrophage-associated Diseases -- Part IV Targeting Macrophages for Treatment of Various Diseases -- Tumor Associated Macrophages as Therapeutic Target for Drug/immune Therapy of Cancer -- Macrophage Targeting for Therapy of Autoimmune Diseases -- Macrophage Targeting for Therapy of Cardiovascular Diseases (CVD) -- Macrophage targeting for therapy of intracellular infections -- Targeting Drugs and Nucleic Acids to Macrophages for Therapy of Inflammatory Diseases -- Macrophage Targeted Chemotherapy for Tuberculosis and other Respiratory Disease. -- Part V Specific Formulations and Clinical Trials on Macrophage Targeted Delivery -- Nano- and Microparticles Based Dry Powder Inhalers for Pulmonary Macrophage Drug Delivery -- Recent Trends in Clinical Studies on Macrophage Targeted Delivery -- Future Directions and Challenges in Macrophage Targeting. .
    Abstract: The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: XVIII, 556 p. 76 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841645
    URL: https://doi.org/10.1007/978-3-030-84164-5
    DOI: 10.1007/978-3-030-84164-5
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Hydrological Modeling : Hydraulics, Water Resources and Coastal Engineering (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Earth sciences. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Natural disasters. ; Sustainability. ; Water. ; Earth Sciences. ; Environmental Engineering/Biotechnology. ; Natural Hazards. ; Sustainability.
    Description / Table of Contents: Performance improvement of usbr vi stilling basin model for pipe outlet -- Rain water harvesting for the main campus of jaipur national university, jagatpura, Jaipur -- Bio Inspired Genetic Algorithm for Optimal Design of Water Distribution Networks -- Drought assessment using various drought indices: a case study of banaskantha district -- Top surface soil moisture retrieval using c- band synthetic aperture radar over kudremukh grasslands -- Meteorological drought assessment in the bharathapuzha river basin -- Experimental and numerical analysis of mean pressure coefficient on C-shaped building with and without round corner. .
    Abstract: This book carefully considers hydrological models which are essential for predicting floods, droughts, soil moisture estimation, land use change detection, geomorphology and water structures. The book highlights recent advances in the area of hydrological modelling in the Ganga Basin and other internationally important river basins. The impact of climate change on water resources is a global concern. Water resources in many countries are already stressed, and climate change along with burgeoning population, rising standard of living and increasing demand are adding to the stress. Furthermore, river basins are becoming less resilient to climatic vagaries. Fundamental to addressing these issues is hydrological modelling which is covered in this book. Integrated water resources management is vital to ensure water and food security. Integral to the management is groundwater and solute transport, and this book encompasses tools that will be useful to mitigate the adverse consequences of natural disasters.
    Type of Medium: Online Resource
    Pages: X, 526 p. 289 illus., 219 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030813581
    Series Statement: Water Science and Technology Library, 109
    URL: https://doi.org/10.1007/978-3-030-81358-1
    DOI: 10.1007/978-3-030-81358-1
    DDC: 551.48
    Language: English
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  • 4
    Online Resource
    Online Resource
    Hydrological Extremes : River Hydraulics and Irrigation Water Management (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Food security. ; Natural disasters. ; Environmental monitoring. ; Sustainability. ; Water. ; Food Security. ; Natural Hazards. ; Environmental Monitoring. ; Sustainability.
    Description / Table of Contents: Intelligent Irrigation Water Management -- River Hydraulics -- Assessment and Monitoring of Hydrological Extremes -- Future Scenarios.
    Abstract: This book presents quality technical papers representing the recent developments in the field of hydrological modeling, water management and water governance including practical applications. The content covers multifarious aspects of hydrology and water resources. It includes an application of the Hydrologic Modelling System (HEC-HMS) which has been successfully demonstrated for assessment of floods. The authors suggest an approach for the mitigation of cyclone disaster through a case study of the Phailin cyclone, whilst considering mitigating pluvial flooding, developing suitable management strategies. The book includes chapters discussing the detrended fluctuation analysis which is carried out for multifractal description of droughts. Drought characteristics are analyzed, and drought indices evolved for drought preparedness/management. The use of science in community planning under changing climate is also studied and discussed. The authors present and experimental study wherein hydraulic coefficients are calibrated by using vertical orifice. A cross flow hybrid hydrokinetic turbine is also evaluated for performance, and high head regulating radial gate designed and studied its sensitivity. This book will appeal to researchers, field practitioners, NGO and other Governmental as well as private water practitioners .
    Type of Medium: Online Resource
    Pages: XII, 446 p. 262 illus., 230 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030591489
    Series Statement: Water Science and Technology Library, 97
    URL: https://doi.org/10.1007/978-3-030-59148-9
    DOI: 10.1007/978-3-030-59148-9
    DDC: 551.48
    Language: English
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