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  • 1
    Online Resource
    Online Resource
    The Carbonic Anhydrases: Current and Emerging Therapeutic Targets (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Description / Table of Contents: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Abstract: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Type of Medium: Online Resource
    Pages: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030795115
    Series Statement: Progress in Drug Research, 75
    URL: https://doi.org/10.1007/978-3-030-79511-5
    DOI: 10.1007/978-3-030-79511-5
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Expertise Under Scrutiny : 21st Century Decision Making for Environmental Health and Safety (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Operations research. ; Environmental health. ; Environmental monitoring. ; Environmental Management. ; Operations Research and Decision Theory. ; Environmental Health. ; Environmental Monitoring.
    Description / Table of Contents: The Classic Challenge of Good Decision Making -- About Expertise Problems: Decision Making Challenges in a Contentious Environment -- Actors and Experts in the Decision Making Process -- Critical Challenges and Difficulties in Safety, Security, Environment and Health: Why are we often so bad at managing SSEH Problems?- Ethics and Analytics as Key Drivers of Good Decisions -- Solving Problems in SSEH: The Use of Decision Support Tools -- Decision Making, ELECTRE, and SSEH -- Navigating Decisions in a 21st Century World -- References.
    Abstract: This book explores the challenges that confront leaders in government and industry when making decisions in the areas of environmental health and safety. Today, decision making demands transparency, robustness, and resiliency. However thoughtfully they are devised, decisions made by governments and enterprises can often trigger immediate, passionate public response. Expertise Under Scrutiny shows how leaders can establish organizational decision making processes that yield valid, workable choices even in fast-changing and uncertain conditions. The first part of the book examines the organizational decision making process, describing the often-contentious environment in which important environmental health and safety decisions are made, and received. The authors review the roles of actors and experts in the decision making process. The book goes on to address such topics as: · The roles of actors and experts in the decision making process · Ethics and analytics as drivers of good decisions · Why managing problems in safety, security, environment, and health Part II offers an outline for adopting a formal decision support structure, including the use of decision support tools. It includes a chapter devoted to ELECTRE (ELimination and Choice Expressing Reality), a multi-criteria decision analysis system. The book concludes with an insightful appraisal and analysis of the expertise, structure and resources needed for navigating well-supported, risk-informed decisions in our 21st Century world. Expertise Under Scrutiny benefits a broad audience of students, academics, researchers, and working professionals in management and related disciplines, especially in the field of environmental health and safety.
    Type of Medium: Online Resource
    Pages: XVI, 168 p. 45 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030205324
    Series Statement: Risk, Systems and Decisions,
    URL: https://doi.org/10.1007/978-3-030-20532-4
    DOI: 10.1007/978-3-030-20532-4
    DDC: 333.7
    Language: English
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  • 3
    Online Resource
    Online Resource
    Machine Learning Techniques for Smart City Applications: Trends and Solutions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Machine learning. ; Artificial intelligence. ; Medical policy. ; Transportation engineering. ; Traffic engineering. ; Business logistics. ; Machine Learning. ; Artificial Intelligence. ; Intelligence Infrastructure. ; Health Policy. ; Transportation Technology and Traffic Engineering. ; Logistics.
    Description / Table of Contents: Applying Deep Learning to Predict Civic Purpose Development: Within the Smart City Context -- Convolution Neural Network Scheme for Detection of Electricity Theft in Smart Grids -- Helping Hand: A GMM Based Real time Assistive Device for Disabled Using Hand Gestures -- A Review on Hand Gesture and Sign Language Techniques for Hearing Impaired Person -- DriveSense: Adaptive System for Driving Behaviour Analysis and Ranking -- Classification and Tracking of Vehicles Using Videos Captured by Unmanned Aerial Vehicles -- Tracking Everyone and Everything in Smart Cities with an ANN Driven Smart Antenna -- Wavelet based Saliency and Ensemble Classifier for Pedestrian Detection in Infrared Images -- A Survey of Emerging Applications of Machine Learning in the Diagnosis and Management of Sleep Hygiene and Health in the Elderly Population -- Smart City Traffic Patterns Prediction Using Machine Learning.
    Abstract: This book discusses the application of different machine learning techniques to the sub-concepts of smart cities such as smart energy, transportation, waste management, health, infrastructure, etc. The focus of this book is to come up with innovative solutions in the above-mentioned issues with the purpose of alleviating the pressing needs of human society. This book includes content with practical examples which are easy to understand for readers. It also covers a multi-disciplinary field and, consequently, it benefits a wide readership including academics, researchers, and practitioners.
    Type of Medium: Online Resource
    Pages: VIII, 226 p. 179 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031088599
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-031-08859-9
    DOI: 10.1007/978-3-031-08859-9
    DDC: 006.31
    Language: English
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  • 4
    Online Resource
    Online Resource
    The Science and Business of Drug Discovery : Demystifying the Jargon (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacovigilance. ; Pharmaceutical chemistry. ; Chemistry, Physical and theoretical. ; Biotechnology. ; Pharmacology. ; Drug Safety and Pharmacovigilance. ; Pharmaceutics. ; Theoretical Chemistry. ; Biotechnology.
    Description / Table of Contents: Introduction -- PART 1: How Drugs are Discovered and Developed in the Pharmaceutical Industry -- Introduction to Drugs and Drug Targets -- Background to chemistry of small and large molecules -- Laying the foundations- Drug discovery from antiquity to the twenty first century -- Part II-The drug development pipeline – discovery to testing in humans -- Drug discovery pipeline overview -- Target discovery -- Medicinal chemistry -- Biotherapeutics -- Screening for hits -- Process chemistry and formulation -- Preclinical development -- Part III-The drug development pipeline – clinical trials to marketing authorisation -- Clinical trials -- Regulatory affairs and marketing approval -- Diagnostics and personalized medicine -- Putting it All Together: a drug development case history -- Part IV- The Global Pharmaceuticals Business -- Commercial aspects of drug development -- Challenges and responses -- Part V - Professional Interactions with the Drug Discovery Industry.-Professional Interactions with the Drug Discovery Industry: Technology Transfer Executives -- Recruitment Executives -- Pharmaceutical translators and Interpreters.
    Abstract: The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the twenty chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators .
    Type of Medium: Online Resource
    Pages: XVII, 402 p. 102 illus., 20 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030578145
    URL: https://doi.org/10.1007/978-3-030-57814-5
    DOI: 10.1007/978-3-030-57814-5
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Climate Resilience and Environmental Sustainability Approaches : Global Lessons and Local Challenges (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Environment. ; Environmental management. ; Environmental monitoring. ; Environmental chemistry. ; Environmental Sciences. ; Environmental Management. ; Environmental Monitoring. ; Environmental Chemistry. ; Environmental Monitoring.
    Description / Table of Contents: 1 Climate resilience and Environmental Sustainability Approaches - An Introduction -- Part 1 -- Climate Change, Mitigation, and Sustainable -- 2 Progress in Climate Change Downscaling Simulations in Southeast Asia -- 3 Climate Change Signatures over Schirmacher Oasis, Antarctica -- 4 REDD+ in Indian context: Planning and Implementation Scenario -- 5 Climate Change Impacts, Vulnerability and Mitigation in the Indian Ocean Region: Policy Suggestions -- 6 Climate change, Agriculture adaptation and Sustainability -- 7 Enhancing climate service delivery mechanisms in agriculture sector to cope with climate change -- 8 Agrometeorological Services for Climate Resilient Agriculture -- 9 Microbial diversity and Multifunctional microbial biostimulants for Agricultural Sustainability -- 10 Adoption of Vertical Farming Technique for Sustainable Agriculture -- Part 2 -- Environmental Sustainability -- (Alternate Energy, Ecofriendly Waste Management and Sustainable Approaches) -- 11 Sustainability of Biofuels: The dynamic nexus between CO2 emissions and bioenergy consumption in OECD Countries -- 12 Challenges and Solution for Renewable Energy (RE) Development in Uttarkahand, India -- 13 Integrated Wastewater Treatment and Energy Production using Microbial Fuel Cell Technology: A Sustainable Environment Management Approach -- 14 Carbon Footprinting: A Study of Plywood Industry in District Yamunanagar (India) -- 15 Ecofriendly Bioremediation Approach for Dye Removal from Wastewaters: Challenges and Prospects -- 16 Degradation and biotransformation of pentachlorophenol by microorganisms -- 17 Sustainable Solid Waste Management in India – Practices, Challenges and the Way Forward -- 18 Social Enterprises as an Emerging Platform in Waste Management -- 19 Understanding linkages between Sustainability and Traditional Ethnoecological Knowledge (TEK): A case study of Paudi Bhuyans in Northern Odisha, India -- 20 Achieving Sustainable Development Goals (SDGs): Challenges and Preparation in Bangladesh -- 21 Sustainable Health care under Ayushman Bharat Initiative in India: Role of Institutional CSR. .
    Abstract: The book is about climate resilience and environmental sustainability approaches, discussing knowledge at global level and the local challenges, presented by authors from various countries. Environmental sustainability is at stake and implications of climate change are clearly visible in most parts of the world. In the times of the prevailing global environmental crisis, this book discusses key issues of climate change and sustainable energy alternatives, waste management and development. It discusses climate change scenario using simulation models in various Asian countries, signatures of climate change in Antarctica, implications in the Indian Ocean and the Indian scenario of REDD+. A special focus has been given on building climate resilience in our agricultural ecosystems and sustainable agriculture. It discusses the prospects and challenges of renewable energy options including biofuels and energy from wastewaters, explores the technical aspects of eco-friendly bioremediation of pollutants, sustainable solid waste management practices and challenges, carbon footprints of industry, and emphasizes on the significance of combining traditional knowledge with modern technology with novel approaches including involvement of social enterprises and corporate social responsibility to achieve the Sustainable Development Goals. This is an important document for researchers and policy makers working in multidisciplinary fields of sustainability sciences.
    Type of Medium: Online Resource
    Pages: XVI, 415 p. 69 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811609022
    URL: https://doi.org/10.1007/978-981-16-0902-2
    DOI: 10.1007/978-981-16-0902-2
    DDC: 333.7
    Language: English
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  • 6
    Online Resource
    Online Resource
    Beyond Belief : Opportunities for Faith-Engaged Approaches to Climate-Change Adaptation in the Pacific Islands (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Environmental Sciences.
    Description / Table of Contents: Looking back to the future: the clash of religion and secularism -- The roots of spirituality and religion in the Pacific islands region -- Religion as culture, religion for wellbeing -- Weaving worldviews: science and spirituality together -- Belief and action: a way forward -- Faith for survival.
    Abstract: This interdisciplinary book explores the science and spirituality nexus in the Pacific Islands Region and as such makes a critical contribution to sustainable climate change adaptation in Oceania. In addition to presenting case studies, literary analyses, field projects, and empirical research, the book describes faith-engaged approaches through the prism of: • Context: past, present, and future prospects • Theory: concepts, narratives, and theoretical frameworks • Practice: empirical research and praxis-informed case examples • Doctrine: scriptural contributions and perspectives • Engagement: enlisting religious stakeholders and constituencies Comprising peer-reviewed works by scholars, professionals, and practitioners from across Oceania, the book closes a critical gap in the literature and represents a groundbreaking contribution to holistic climate change adaptation in the Pacific Islands Region that is scientifically sound, spiritually attuned, locally meaningful, and contextually compelling.
    Type of Medium: Online Resource
    Pages: XIV, 391 p. 31 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030676025
    Series Statement: Climate Change Management,
    URL: https://doi.org/10.1007/978-3-030-67602-5
    DOI: 10.1007/978-3-030-67602-5
    DDC: 333.7
    Language: English
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  • 7
    Online Resource
    Online Resource
    Recreational Disturbance of Shorebirds in Tropical Asia (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Environmental geography. ; Environmental Management. ; Integrated Geography.
    Description / Table of Contents: Chapter 1 -- Shorebirds and Recreation in Coastal Zones (Greg D. Simpson) -- Chapter 2. Interrogating the Recreational Disturbance Literature (Greg D. Simpson) -- Chapter 3. Main Sources of Recreational Disturbance (Sumudu Marasinghe) -- Chapter 4. How Recreational Disturbances affect Coastal Birds? Some Case Studies from Sri Lanka (Sumudu Marasinghe) -- Chapter 5. Setting the Management and Research Agendas (David Newsome).
    Abstract: Much of that growing demand for coastal recreation and tourism has focused on countries in South and Southeast Asia in the tourism megaregion that this book refers to as Tropical Asia. As such, the recreational disturbance of shorebirds in Asia is a serious conservation issue, at a time when populations of both migratory and non-migratory species of shorebirds are threatened and declining because of the loss of coastal habitat and increased human disturbance. Despite global awareness about the impacts that the growth of coastal recreation and tourism across Tropical Asia is likely to be having on threatened and endangered migratory and resident shorebird species of the coastal zones of the East Asian– Australasian Flyway, less than 3% of the published peer-reviewed research into the recreational disturbance of shorebirds addresses coastal zones of Tropical Asia. This situation points to a significant knowledge gap regarding the impacts of human recreation on shorebirds in the Tropical Asian region. In contrast, almost three quarters of the peer-reviewed articles that report recreational disturbance research and management strategies focus on coastal zones in North America (36%), Oceania (20%), and Europe (20%). For those reasons, the quantitative systematic literature review and research case study from Sri Lanka reported in this book provide a call to action and recommendations for both management approaches grounded in the international literature and a research agenda that should be implemented in the coastal zones of Tropical Asia.
    Type of Medium: Online Resource
    Pages: XIII, 97 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031139680
    Series Statement: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-031-13968-0
    DOI: 10.1007/978-3-031-13968-0
    DDC: 333.7
    Language: English
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  • 8
    Online Resource
    Online Resource
    Restoration of Wetland Ecosystem: A Trajectory Towards a Sustainable Environment (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Environmental management. ; Sustainability. ; Environment. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Environmental Management. ; Sustainability. ; Environmental Sciences. ; Freshwater and Marine Ecology. ; Pollution.
    Description / Table of Contents: 1. Restoration, construction and conservation of degrading wetlands: A step towards sustainable management practices -- 2. Phytoremediation and sustainable developmental policies and practices -- 3. Wetland as a sustainable reservoir of ecosystem services: Prospects of threat and conservation -- 4. Carbon sequestration by wetlands in the climate change scenario -- 5. Wetlands: A major natural source responsible for methane emissions -- 6. Wetland conservation and restoration of ecosystem services and halt biodiversity loss: An India Prospectives -- 7. Microbes biology: Microbes in wetland and bioprospection of microbes -- 8. Contribution of Microbes in the renovation of wetland -- 9. Phytoremediation: Role of Mycorrhiza in plant responses to Stress -- 10. Integrated approach for bioremediation and biofuel production using algae -- 11. Dual role of Microalgae: Phycoremediation coupled with biomass generation for biofuel production -- 12. Microalgae and microorganisms- important regulators of Carbon dynamics in wetland ecosystem -- 13. Bioremediation of heavy metals: A new approach to sustainable agriculture -- 14. Waste water treatment through Nannotechnology: Role and Perspects.
    Abstract: The risks and consequences of environmental change are increasing, leading to massive losses in terms of ecosystems and having a huge impact on human populations. As such, global thinkers, environmentalists, scientists and policy makers are focusing on finding solutions and ways to sustain life on Earth. Anthropogenic impacts on the climate system can only be mitigated by the restoration of existing natural resources and the sustainable development of the environment and society. This book discusses the potential of green technology in waste management, wetland restoration, presenting the latest developments in the field of bioenergy, green ecology, bioremediation and microbial management. Wetlands are one of Earth’s most important ecosystems, and they provide valuable services to human societies, such as minimizing the impacts of floods, acting as a carbon sink, and offering water purification as well as recreational opportunities. Wetlands may be natural or constructed, and the effectiveness of wetland services largely depends on the diversity of macrophytes affecting the algal production, plant biomass and nutrient status of the system. In addition, they are one of the richest microbial ecosystems on earth: the rhizosphere, soil and water interface enhances wetland services with implications ranging from phytoremediation to microbial bioprospection. However, in order to function properly, they need to be effectively redesigned, reengineered, protected and maintained. The book addresses the dynamic relation between three global concerns: environmental pollution, resource exploitation and sustainability. It describes the utilization of resources like wastes (municipal, industrial, agricultural, mine drainage, tannery, solid, and e waste), plants, algae and microbes for production of renewable biofuel, biofertilizers and other value added products to achieve the goal of sustainable development. The book also discusses the current and future trends in employing wetlands in improving water quality. In addition it presents the latest international research in the fields of wetland science, waste management, carbon sequestration and bioremediation. Highlighting a broad spectrum of topics and strategies for achieving a sustainable environment, the book offers researchers, students and academics insights into utilizing resources in a sustainable way.
    Type of Medium: Online Resource
    Pages: XV, 247 p. 32 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811376658
    URL: https://doi.org/10.1007/978-981-13-7665-8
    DOI: 10.1007/978-981-13-7665-8
    DDC: 333.7
    Language: English
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  • 9
    Online Resource
    Online Resource
    Recent Advances in Environmental Science from the Euro-Mediterranean and Surrounding Regions (2nd Edition) : Proceedings of 2nd Euro-Mediterranean Conference for Environmental Integration (EMCEI-2), Tunisia 2019 (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Medical physics. ; Industrial management Environmental aspects. ; Environmental Sciences. ; Climate Sciences. ; Medical Physics. ; Corporate Environmental Management.
    Description / Table of Contents: Efficiency of hybrid process of coagulation/flocculation followed by membrane filtration for the treatment of synthetic vegetable oil refinery wastewater -- Fe/clay composite as catalysts for textile wastewater treatment -- Iron removal from groundwater by adsorption process onto activated carbon obtained from Pinus halepensis cone wastes -- Synthesis and characterization of activated carbon from Pinus halepensis cone wastes; Adsorption Prediction as a function of some physicochemical characteristics of activated carbons -- ADSORPTION OF INDUSTRIAL DYE BzR FROM AQUEOUS SOLUTION USING LOCAL MODIFIED CLAY -- Adsorption-desorption of Methylene blue by bentonite from aqueous solution -- Removal of dispersedye from aqueous solution by bottom ash -- Experimental study of the removal of Rhodamine B from aqueous solution by adsorption onto coffee waste -- Electrochemical impedance spectroscopy and adsorption study of carbon steel in 1M HCl solution containing 2-(2-Methoxybenzylidene) Hydrazine-1-Carbothioamide -- Adsorption efficiency of graphene oxide towards cyanine dyes with different alkyl chain lengths -- Cu(II) ions removal on functionalized cellulose beads from Tunisian almond (Prunus dulcis) shell -- Optimization of Cr(III) removal from a synthetic solution and a real tanning effluent by powdered marble using 3-level Box-Behnken design: thermodynamic, toxicity and regeneration studies -- Dynamics Modelling of Multicomponent Metal Ions Removal onto Low Cost Buckwheat Hulls -- Local Materials and Solid Waste (Sawdust) Valorization in The Treatment of Industrial synthetic water field -- Cationic dye removal using alginate-organobentonite composite beads.
    Abstract: This book includes over three hundred and seventy-five short papers presented during the second EMCEI, which was held in Sousse, Tunisia in October 2019. After the success of the first EMCEI in 2017, the second installment tackled emerging environmental issues together with new challenges, e.g. by focusing on innovative approaches that contribute to achieving a sustainable environment in the Mediterranean and surrounding regions and by highlighting to decision makers from related sectors the environmental considerations that should be integrated into their respective activities. Presenting a wide range of environmental topics and new findings relevant to a variety of problems in these regions, this volume will appeal to anyone working in the subject area and particularly to students interested in learning more about new advances in environmental research initiatives in view of the worsening environmental degradation of the Mediterranean and surrounding regions, which has made environmental and resource protection into an increasingly important issue hampering sustainable development and social welfare.
    Type of Medium: Online Resource
    Pages: LXXXIII, 2417 p. 786 illus., 620 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030512101
    Series Statement: Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-51210-1
    DOI: 10.1007/978-3-030-51210-1
    DDC: 333.7
    Language: English
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