ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

1

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A lattice model of foam flow in porous media: A percolation approach (1993)

Laidlaw, W. G. ; Wilson, W. G. ; Coombe, Dennis A.

Springer

In: Transport in Porous Media. 1993; 11(2): 139-159. Published 1993 May 01. doi: 10.1007/bf01059631.

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Publikationsdatum: 1993-05-01

Print ISSN: 0169-3913

Digitale ISSN: 1573-1634

Thema: Geologie und Paläontologie , Technik allgemein

Publiziert von Springer

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2

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The geochemistry of formation waters in the molasse basin of upper Austria (1987)

Andrews, J. N. ; Youngman, M. J. ; Goldbrunner, J. E. ; [weitere]

Springer

In: Environmental Geology. 1987; 10(1): 43-57. Published 1987 Feb 01. doi: 10.1007/bf02588004.

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Publikationsdatum: 1987-02-01

Print ISSN: 0943-0105

Digitale ISSN: 1432-0495

Thema: Geologie und Paläontologie

Publiziert von Springer

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3

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Straightforward discretisation of Green function and free-surface potential flow around a three-dimensional lifting body (2016)

Chen, Zhi-Min ; Liu, Qiang ; Price, W. G.

Springer

In: Journal of Marine Science and Technology. 2016; 22(1): 149-161. Published 2016 Jul 09. doi: 10.1007/s00773-016-0400-3.

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Publikationsdatum: 2016-07-09

Print ISSN: 0948-4280

Digitale ISSN: 1437-8213

Thema: Geologie und Paläontologie , Technik allgemein

Publiziert von Springer

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4

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Petrochemical comparison of 3.5 Ga old mafic amphibolite inclusions from eastern Hebei province with Archean mafic — ultramafic supracrustals of uncertain antiquity, southern Jilin eastern Liaoning provinces, China (1989)

Ernst, W. G.

Springer

In: Chinese Journal of Geochemistry. 1989; 8(2): 97-111. Published 1989 Apr 01. doi: 10.1007/bf02840434.

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Publikationsdatum: 1989-04-01

Print ISSN: 1000-9426

Digitale ISSN: 1993-0364

Thema: Chemie und Pharmazie , Geologie und Paläontologie

Publiziert von Springer

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5

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Response to Comment on "U-Th dating of carbonate crusts reveals Neandertal origin of Iberian cave art" (2018)

Hoffmann, D. L., Standish, C. D., Garcia-Diez, M., Pettitt, P. B., Milton, J. A., Zilhao, J., Alcolea-Gonzalez, J. J., Cantalejo-Duarte, P., Collado, H., de Balbin, R., Lorblanchet, M., Ramos-Munoz, J., Weniger, G.- C., Pike, A. W. G.

American Association for the Advancement of Science (AAAS)

In: Science

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Publikationsdatum: 2018-10-12

Beschreibung: Slimak et al . challenge the reliability of our oldest (〉65,000 years) U-Th dates on carbonates associated with cave paintings in Spain. They cite a supposed lack of parietal art for the 25,000 years following this date, along with potential methodological issues relating to open-system behavior and corrections to detrital or source water 230 Th. We show that their criticisms are unfounded.

Schlagwort(e): Anthropology

Print ISSN: 0036-8075

Digitale ISSN: 1095-9203

Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von American Association for the Advancement of Science (AAAS)

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6

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Beyond the molecular movie: Dynamics of bands and bonds during a photoinduced phase transition (2018)

Nicholson, C. W., Lücke, A., Schmidt, W. G., Puppin, M., Rettig, L., Ernstorfer, R., Wolf, M.

American Association for the Advancement of Science (AAAS)

In: Science

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Publikationsdatum: 2018-11-16

Beschreibung: Ultrafast nonequilibrium dynamics offer a route to study the microscopic interactions that govern macroscopic behavior. In particular, photoinduced phase transitions (PIPTs) in solids provide a test case for how forces, and the resulting atomic motion along a reaction coordinate, originate from a nonequilibrium population of excited electronic states. Using femtosecond photoemission, we obtain access to the transient electronic structure during an ultrafast PIPT in a model system: indium nanowires on a silicon(111) surface. We uncover a detailed reaction pathway, allowing a direct comparison with the dynamics predicted by ab initio simulations. This further reveals the crucial role played by localized photoholes in shaping the potential energy landscape and enables a combined momentum- and real-space description of PIPTs, including the ultrafast formation of chemical bonds.

Schlagwort(e): Physics

Print ISSN: 0036-8075

Digitale ISSN: 1095-9203

Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von American Association for the Advancement of Science (AAAS)

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7

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Recruiting more proteins to the RNA world (2018)

Scott, W. G., Nagai, K.

American Association for the Advancement of Science (AAAS)

In: Science

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Publikationsdatum: 2018-11-09

Schlagwort(e): Biochemistry

Print ISSN: 0036-8075

Digitale ISSN: 1095-9203

Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von American Association for the Advancement of Science (AAAS)

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8

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VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma (2018)

Zhang, J., Wu, T., Simon, J., Takada, M., Saito, R., Fan, C., Liu, X.-D., Jonasch, E., Xie, L., Chen, X., Yao, X., Teh, B. T., Tan, P., Zheng, X., Li, M., Lawrence, C., Fan, J., Geng, J., Liu, X., Hu, L., Wang, J., Liao, C., Hong, K., Zurlo, G., Parker, J. S., Auman, J. T., Perou, C. M., Rathmell, W. K., Kim, W. Y., Kirschner, M. W., Kaelin, W. G., Baldwin, A. S., Zhang, Q.

American Association for the Advancement of Science (AAAS)

In: Science

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Publikationsdatum: 2018-07-20

Beschreibung: Inactivation of the von Hippel-Lindau (VHL) E3 ubiquitin ligase protein is a hallmark of clear cell renal cell carcinoma (ccRCC). Identifying how pathways affected by VHL loss contribute to ccRCC remains challenging. We used a genome-wide in vitro expression strategy to identify proteins that bind VHL when hydroxylated. Zinc fingers and homeoboxes 2 (ZHX2) was found as a VHL target, and its hydroxylation allowed VHL to regulate its protein stability. Tumor cells from ccRCC patients with VHL loss-of-function mutations usually had increased abundance and nuclear localization of ZHX2. Functionally, depletion of ZHX2 inhibited VHL-deficient ccRCC cell growth in vitro and in vivo. Mechanistically, integrated chromatin immunoprecipitation sequencing and microarray analysis showed that ZHX2 promoted nuclear factor B activation. These studies reveal ZHX2 as a potential therapeutic target for ccRCC.

Schlagwort(e): Cell Biology, Medicine, Diseases

Print ISSN: 0036-8075

Digitale ISSN: 1095-9203

Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von American Association for the Advancement of Science (AAAS)

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9

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Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma (2018)

Miao, D., Margolis, C. A., Gao, W., Voss, M. H., Li, W., Martini, D. J., Norton, C., Bosse, D., Wankowicz, S. M., Cullen, D., Horak, C., Wind-Rotolo, M., Tracy, A., Giannakis, M., Hodi, F. S., Drake, C. G., Ball, M. W., Allaf, M. E., Snyder, A., Hellmann, M. D., Ho, T., Motzer, R. J., Signoretti, S., Kaelin, W. G., Choueiri, T. K., Van Allen, E. M.

American Association for the Advancement of Science (AAAS)

In: Science

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Publikationsdatum: 2018-02-16

Beschreibung: Immune checkpoint inhibitors targeting the programmed cell death 1 receptor (PD-1) improve survival in a subset of patients with clear cell renal cell carcinoma (ccRCC). To identify genomic alterations in ccRCC that correlate with response to anti–PD-1 monotherapy, we performed whole-exome sequencing of metastatic ccRCC from 35 patients. We found that clinical benefit was associated with loss-of-function mutations in the PBRM1 gene ( P = 0.012), which encodes a subunit of the PBAF switch-sucrose nonfermentable (SWI/SNF) chromatin remodeling complex. We confirmed this finding in an independent validation cohort of 63 ccRCC patients treated with PD-1 or PD-L1 (PD-1 ligand) blockade therapy alone or in combination with anti–CTLA-4 (cytotoxic T lymphocyte-associated protein 4) therapies ( P = 0.0071). Gene-expression analysis of PBAF-deficient ccRCC cell lines and PBRM1 -deficient tumors revealed altered transcriptional output in JAK-STAT (Janus kinase–signal transducers and activators of transcription), hypoxia, and immune signaling pathways. PBRM1 loss in ccRCC may alter global tumor-cell expression profiles to influence responsiveness to immune checkpoint therapy.

Schlagwort(e): Medicine, Diseases

Print ISSN: 0036-8075

Digitale ISSN: 1095-9203

Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von American Association for the Advancement of Science (AAAS)

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10

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U-Th dating of carbonate crusts reveals Neandertal origin of Iberian cave art (2018)

Hoffmann, D. L., Standish, C. D., Garcia-Diez, M., Pettitt, P. B., Milton, J. A., Zilhao, J., Alcolea-Gonzalez, J. J., Cantalejo-Duarte, P., Collado, H., de Balbin, R., Lorblanchet, M., Ramos-Munoz, J., Weniger, G.- C., Pike, A. W. G.

American Association for the Advancement of Science (AAAS)

In: Science

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Publikationsdatum: 2018-02-23

Beschreibung: The extent and nature of symbolic behavior among Neandertals are obscure. Although evidence for Neandertal body ornamentation has been proposed, all cave painting has been attributed to modern humans. Here we present dating results for three sites in Spain that show that cave art emerged in Iberia substantially earlier than previously thought. Uranium-thorium (U-Th) dates on carbonate crusts overlying paintings provide minimum ages for a red linear motif in La Pasiega (Cantabria), a hand stencil in Maltravieso (Extremadura), and red-painted speleothems in Ardales (Andalucía). Collectively, these results show that cave art in Iberia is older than 64.8 thousand years (ka). This cave art is the earliest dated so far and predates, by at least 20 ka, the arrival of modern humans in Europe, which implies Neandertal authorship.

Schlagwort(e): Anthropology

Print ISSN: 0036-8075

Digitale ISSN: 1095-9203

Thema: Biologie , Chemie und Pharmazie , Geologie und Paläontologie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von American Association for the Advancement of Science (AAAS)

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