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  • Articles  (46)
  • Latest Papers from Table of Contents or Articles in Press  (46)
  • BioMed Central  (20)
  • Molecular Diversity Preservation International  (11)
  • MDPI Publishing  (9)
  • International Union of Crystallography  (3)
  • Public Library of Science  (3)
  • American Chemical Society (ACS)
  • Molecular Diversity Preservation International (MDPI)
  • Biology  (29)
  • Energy, Environment Protection, Nuclear Power Engineering  (17)
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  • Articles  (46)
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  • Latest Papers from Table of Contents or Articles in Press  (46)
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  • 1
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    IJERPH, Vol. 12, Pages 2532-2542: Physiological and Psychological Effects of Forest Therapy on Middle-Aged Males with High-Normal Blood Pressure (2015)
    MDPI Publishing
    Details
    Publication Date: 2015-02-26
    Description: Time spent walking and relaxing in a forest environment (“forest bathing” or “forest therapy”) has well demonstrated anti-stress effects in healthy adults, but benefits for ill or at-risk populations have not been reported. The present study assessed the physiological and psychological effects of forest therapy (relaxation and stress management activity in the forest) on middle-aged males with high-normal blood pressure. Blood pressure and several physiological and psychological indices of stress were measured the day before and approximately 2 h following forest therapy. Both pre- and post-treatment measures were conducted at the same time of day to avoid circadian influences. Systolic and diastolic blood pressure (BP), urinary adrenaline, and serum cortisol were all significantly lower than baseline following forest therapy (p 〈 0.05). Subjects reported feeling significantly more “relaxed” and “natural” according to the Semantic Differential (SD) method. Profile of Mood State (POMS) negative mood subscale scores for “tension-anxiety,” “confusion,” and “anger-hostility,” as well as the Total Mood Disturbance (TMD) score were significantly lower following forest therapy. These results highlight that forest is a promising treatment strategy to reduce blood pressure into the optimal range and possibly prevent progression to clinical hypertension in middle-aged males with high-normal blood pressure.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI Publishing
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  • 2
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    IJERPH, Vol. 9, Pages 1398-1410: Eating Behavior and Childhood Overweight Among Population-Based Elementary Schoolchildren in Japan (2012)
    MDPI Publishing
    Details
    Publication Date: 2012-04-17
    Description: This study investigated the relationship between eating behavior and childhood overweight among population-based elementary schoolchildren in Japan. Data was collected from fourth graders (9 or 10 years of age) from Ina Town, Saitama Prefecture, Japan from 1999 to 2009. Information about subjects’ sex, age, and lifestyle, including eating behaviors (eating until full and chewing thoroughly), was obtained using a self-administered questionnaire, and height and weight were measured directly. Overweight was determined according to the definition established by the International Obesity Task Force. Data from 4027 subjects (2079 boys and 1948 girls) were analyzed. Chewing thoroughly was associated with a significantly decreased odds ratio (OR) for being overweight, whereas eating until full significantly increased the OR for being overweight (OR: 1.50, 95% confidence interval: 1.16–1.94) among boys. However, eating until full was not associated with a significantly increased OR for being overweight among the group that reported chewing thoroughly, whereas it was associated with a significantly increased OR for being overweight (2.02, 1.38–2.94) among boys who did not chew thoroughly. In conclusion, eating until full or not chewing thoroughly was associated with being overweight among elementary schoolchildren. Results of this study suggest that chewing thoroughly may be an avenue to explore childhood overweight prevention efforts.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI Publishing
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  • 3
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    IJERPH, Vol. 12, Pages 15222-15232: Physiological and Psychological Effects of a Forest Therapy Program on Middle-Aged Females (2015)
    MDPI Publishing
    Details
    Publication Date: 2015-12-02
    Description: The natural environment is increasingly recognized as an effective counter to urban stress, and “Forest Therapy” has recently attracted attention as a relaxation and stress management activity with demonstrated clinical efficacy. The present study assessed the physiological and psychological effects of a forest therapy program on middle-aged females. Seventeen Japanese females (62.2 ± 9.4 years; mean ± standard deviation) participated in this experiment. Pulse rate, salivary cortisol level, and psychological indices were measured on the day before forest therapy and on the forest therapy day. Pulse rate and salivary cortisol were significantly lower than baseline following forest therapy, indicating that subjects were in a physiologically relaxed state. Subjects reported feeling significantly more “comfortable,” “relaxed,” and “natural” according to the semantic differential (SD) method. The Profile of Mood State (POMS) negative mood subscale score for “tension–anxiety” was significantly lower, while that for “vigor” was significantly higher following forest therapy. Our study revealed that forest therapy elicited a significant (1) decrease in pulse rate, (2) decrease in salivary cortisol levels, (3) increase in positive feelings, and (4) decrease in negative feelings. In conclusion, there are substantial physiological and psychological benefits of forest therapy on middle-aged females.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI Publishing
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  • 4
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    IJERPH, Vol. 9, Pages 1398-1410: Eating Behavior and Childhood Overweight Among Population-Based Elementary Schoolchildren in Japan (2012)
    MDPI Publishing
    Details
    Publication Date: 2012-05-03
    Description: This study investigated the relationship between eating behavior and childhood overweight among population-based elementary schoolchildren in Japan. Data was collected from fourth graders (9 or 10 years of age) from Ina Town, Saitama Prefecture, Japan from 1999 to 2009. Information about subjects’ sex, age, and lifestyle, including eating behaviors (eating until full and chewing thoroughly), was obtained using a self-administered questionnaire, and height and weight were measured directly. Overweight was determined according to the definition established by the International Obesity Task Force. Data from 4027 subjects (2079 boys and 1948 girls) were analyzed. Chewing thoroughly was associated with a significantly decreased odds ratio (OR) for being overweight, whereas eating until full significantly increased the OR for being overweight (OR: 1.50, 95% confidence interval: 1.16–1.94) among boys. However, eating until full was not associated with a significantly increased OR for being overweight among the group that reported chewing thoroughly, whereas it was associated with a significantly increased OR for being overweight (2.02, 1.38–2.94) among boys who did not chew thoroughly. In conclusion, eating until full or not chewing thoroughly was associated with being overweight among elementary schoolchildren. Results of this study suggest that chewing thoroughly may be an avenue to explore childhood overweight prevention efforts.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI Publishing
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  • 5
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    Energies, Vol. 5, Pages 599-604: Using Submarine Heat Pumps for Efficient Gas Production from Seabed Hydrate Reservoirs (2012)
    MDPI Publishing
    In: Energies
    Details
    Publication Date: 2012-05-03
    Description: This article reports our novel idea about the thermal stimulation of seabed hydrate reservoirs for the purpose of natural gas production. Our idea is to use submarine heat pumps, which are to be placed near the hydrate reservoir and work to recover thermal energy from the surrounding seawater and supply it into the reservoir. Although the heat pumps need an electricity supply from the sea surface level, they can provide thermal energy which is several times that of the consumed electricity in quantity. As a consequence, the use of submarine heat pumps has a distinct thermodynamic advantage over other thermal stimulation techniques already proposed in the literature.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by MDPI Publishing
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  • 6
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    Energies, Vol. 5, Pages 599-604: Using Submarine Heat Pumps for Efficient Gas Production from Seabed Hydrate Reservoirs (2012)
    MDPI Publishing
    In: Energies
    Details
    Publication Date: 2012-03-03
    Description: This article reports our novel idea about the thermal stimulation of seabed hydrate reservoirs for the purpose of natural gas production. Our idea is to use submarine heat pumps, which are to be placed near the hydrate reservoir and work to recover thermal energy from the surrounding seawater and supply it into the reservoir. Although the heat pumps need an electricity supply from the sea surface level, they can provide thermal energy which is several times that of the consumed electricity in quantity. As a consequence, the use of submarine heat pumps has a distinct thermodynamic advantage over other thermal stimulation techniques already proposed in the literature.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by MDPI Publishing
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  • 7
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    Isolation and sequencing of swine carbonic anhydrase VI, an enzyme expressed in the swine kidney (2014)
    BioMed Central
    Details
    Publication Date: 2014-03-01
    Description: Background: Carbonic anhydrase VI (CA-VI) is produced by the salivary gland and is secreted into the saliva. Although CA-VI is found in the epithelial cells of distal straight tubule of swine kidneys, the exact function of CA-VI in the kidneys remains unclear. Results: CA-VI was located in the epithelial cells of distal straight tubule of swine kidneys.A full-length cDNA clone of CA-VI was generated from the swine parotid gland by reverse transcription polymerase chain reaction, using degenerate primers designed based on conserved regions of the same locus in human and bovine tissues.The cDNA sequence was 1348 base pairs long and was predicted to encode a 317 amino acid polypeptide with a putative signal peptide of 17 amino acids. The deduced amino acid sequence of mature CA-VI was most similar (77.4%) to that of human CA-VI. CA-VI expression was confirmed in both normal and nephritic kidneys, as well as parotid. As the primers used in this study spanned two exons, the influence of genomic DNA was not detected. The expression of CA-VI was demonstrated in both normal and nephritic kidneys, and mRNA of CA-VI in the normal kidneys which was the normalised to an endogenous beta-actin was 0.098 +/- 0.047, while it was significantly lower in the diseased kidneys (0.012 +/- 0.007). The level of CA-VI mRNA in normal kidneys was 19-fold lower than that of the parotid gland (1.887). Conclusions: The localisation of CA-VI indicates that it may play a specialised role in the kidney.
    Electronic ISSN: 1756-0500
    Topics: Biology , Medicine
    Published by BioMed Central
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  • 8
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    The genetic association study between polymorphisms in uncoupling protein 2 and uncoupling protein 3 and metabolic data in dogs (2014)
    BioMed Central
    Details
    Publication Date: 2014-12-13
    Description: Background: The uncoupling proteins (UCPs) in the mitochondrial inner membrane are members of the mitochondrial anion carrier protein family that play an important role in energy homeostasis. Genetic association studies have shown that human UCP2 and UCP3 variants (SNPs and indels) are associated with obesity, insulin resistance, type 2 diabetes mellitus, and metabolic syndrome. The aim of this study was to examine the genetic association between polymorphisms in UCP2 and UCP3 and metabolic data in dogs. Results: We identified 10 SNPs (9 intronic and 1 exonic) and 4 indels (intronic) in UCP2, and 13 SNPs (11 intronic and 2 exonic) and one indel (exonic) in UCP3, by DNA sequence analysis of 11 different dog breeds (n = 119). An association study between these UCP2 and UCP3 variants and the biochemical parameters of glucose, total cholesterol, lactate dehydrogenase and triglyceride in Labrador Retrievers (n = 50) showed that none of the UCP2 polymorphisms were significantly associated with the levels of these parameters. However, four UCP3 SNPs (intron 1) were significantly associated with total cholesterol levels. In addition, the allele frequencies of two of the four SNPs associated with higher total cholesterol levels in a breed that is susceptible to hypercholesterolemia (Shetland Sheepdogs, n = 30), compared with the control breed (Shiba, n = 30). Conclusion: The results obtained from a limited number of individuals suggest that the UCP3 gene in dogs may be associated with total cholesterol levels. The examination of larger sample sizes and further analysis will lead to increased precision of these results.
    Electronic ISSN: 1756-0500
    Topics: Biology , Medicine
    Published by BioMed Central
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  • 9
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    Water, Vol. 5, Pages 1101-1115: Synergistic Water-Treatment Reactors Using a TiO2-Modified Ti-Mesh Filter (2013)
    MDPI Publishing
    In: Water
    Details
    Publication Date: 2013-07-23
    Description: The recent applications of a TiO2-modified Ti-mesh filter (TMiP™) for water purification are summarized with newly collected data including biological assays as well as sewage water treatment. The water purification reactors consist of the combination of a TMiP, a UV lamp, an excimer VUV lamp, and an ozonation unit. The water purification abilities of the reactor were evaluated by decomposition of organic contaminants, inactivation of waterborne pathogens, and treatment efficiency for sewage water. The UV-C/TMiP/O3 reactor disinfected E. coli in aqueous suspension in approximately 1 min completely, and also decreased the number of E. coli in sewage water in 15 min dramatically. The observed rate constants of 7.5 L/min and 1.3 L/min were calculated by pseudo-first-order kinetic analysis respectively. Although organic substances in sewage water were supposed to prevent the UV-C/TMiP/O3 reactor from purifying water, the reactor reduced E. coli in sewage water continuously. On the other hand, although much higher efficiencies for decomposition of organic pollutants in water were achieved in the excimer/TMiP reactor, the disinfection activity of the reactor for waterborne pathogens was not as effective as the other reactors. The difference of efficiency between organic pollutants and waterborne pathogens in the excimer/TMiP reactor may be due to the size, the structure, and the decomposition mechanism of the organic pollutants and waterborne pathogens. These results show that a suitable system assisted by synergy of photocatalysts and other technologies such as ozonation has a huge potential as a practical wastewater purification system.
    Electronic ISSN: 2073-4441
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by MDPI Publishing
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  • 10
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    Mitochondrial DNA 5178 C/A polymorphism influences the effects of habitual smoking on the risk of dyslipidemia in middle-aged Japanese men (2012)
    BioMed Central
    Details
    Publication Date: 2012-08-03
    Description: Background: Several genetic polymorphisms have been reported to modify the effects of smoking on serum lipid levels. The objective of this study was to investigate whether longevity-associated mitochondrial DNA 5178 (Mt5178) C/A polymorphism modifies the effects of habitual smoking on the risk of dyslipidemia in middle-aged Japanese subjects. Methods: A total of 394 male subjects (age, 53.9 +/- 7.9 years; mean +/- SD) were selected from among individuals visiting the hospital for regular medical check-ups. After Mt5178 C/A genotyping, a cross-sectional study assessing the joint effect of Mt5178 C/A polymorphism and cigarette smoking on the risk of hypo-high-density lipoprotein (HDL) cholesterolemia, hyper-low-density lipoprotein (LDL) cholesterolemia or hypertriglyceridemia was conducted. Results: For subjects with Mt5178C, the risk of hypo-HDL cholesterolemia increased with the number of cigarettes smoked daily (P for trend = 0.001). On the other hand, the association between Mt5178A genotype and the risk of hypo-HDL cholesterolemia did not appear to depend on the number of cigarettes smoked daily. For those with Mt5178A, the risk of hyper-LDL cholesterolemia or hypertriglyceridemia increased with cigarettes smoked daily (P for trend = 0.017 and P for trend = 0.002, respectively). However, the association between Mt5178C genotype and the risk of hyper-LDL cholesterolemia or hypertriglyceridemia did not depend on the number of cigarettes smoked daily. Conclusions: The present results suggest that Mt5178 C/A polymorphism modulates the effects of habitual smoking on the risk of dyslipidemia in middle-aged Japanese men.
    Electronic ISSN: 1476-511X
    Topics: Biology
    Published by BioMed Central
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