Publication Date:
2015-10-15
Description:
Article BCG, the only vaccine currently used against tuberculosis, confers only limited protection. Here the authors show that mucosal immunization of macaques with an attenuated strain of Mycobacterium tuberculosis confers a high level of protection from a lethal challenge with the bacterium. Nature Communications doi: 10.1038/ncomms9533 Authors: Deepak Kaushal, Taylor W. Foreman, Uma S. Gautam, Xavier Alvarez, Toidi Adekambi, Javier Rangel-Moreno, Nadia A. Golden, Ann-Marie F. Johnson, Bonnie L. Phillips, Muhammad H. Ahsan, Kasi E. Russell-Lodrigue, Lara A. Doyle, Chad J. Roy, Peter J. Didier, James L. Blanchard, Jyothi Rengarajan, Andrew A. Lackner, Shabaana A. Khader, Smriti Mehra
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
Permalink