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  • Articles  (7,889)
  • Articles: DFG German National Licenses  (7,889)
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  • Articles  (7,889)
  • 11
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of natural products 54 (1991), S. 624-625 
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 176 (1955), S. 1127-1128 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] I observed8 that when extracts of the seeds of Glycine soja (var. Bansei) were absorbed in the cold with human erythrocytes of group O, until they were no longer agglutinated, the extract could still agglutinate A and B cells, not only in the cold, but also at 37 C. Subsequent absorption with ...
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  • 13
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 174 (1954), S. 1015-1015 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Krupe4 has demonstrated the presence of incomplete antibodies in various seeds. The action of seed agglutinins on enzyme-treated cells is now being investigated in our laboratories. The enzyme used is papain and the technique that described by Stratton6. Detailed results will be published in due ...
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  • 14
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 172 (1953), S. 401-402 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The fact that the cells of some species are agglutinated by extracts which fail to agglutinate the cells of other species indicates that the former possess certain red-cell receptors which are lacking in the latter. It was therefore considered instructive to determine the reactions of several plant ...
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  • 15
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 171 (1953), S. 748-748 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] These results support the view that auto-agglutinins are 'non-specific', because they consist of multiple specific components which may exhibit a varying degree of agglutinin linkage3. The multiple specific components may be anti-O (or H), anti-^1, anti-B, and possibly also anti-^, anti-M, anti-JV, ...
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  • 16
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 170 (1952), S. 674-674 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two hundred samples of A and seventy-five of AB cells were therefore tested both with a human anti-^L j. serum and a saline extract of Dolichos bifi orus seeds. All the samples were of Indians of no definite ethnological status and were obtained from the local blood-donor centre; 2 per cent ...
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  • 17
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 190 (1961), S. 146-148 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] RECENTLY, while working with the University of Nottingham Department of Pharmacy Expedition to Spitsbergen, the opportunity arose to study the diurnal temperature variations in a group of 6 men and 2 women, who were subjected to sudden reversal of their activity-sleep and light-darkness schedule. ...
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  • 18
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 184 (1959), S. 109-109 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] An anti-A agglutinin has now been found in the seeds of Hyptis suaveolens, Poit, of the genus Labiatiae. The agglutinin works best when a fresh seed extract is tested on a flat tile which is gently and continuously rocked. Although it is not very avid when tested with erythrocytes suspended in ...
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  • 19
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 9 (1982), S. 0 
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: A fourth human blood group chimaera studied in Birmingham is an example of haemopoietic (twin) chimaerism in which the subject was unaware of being a twin. Chimarerism was discovered during routine antenatal serological investigation in which it was shown that the proposita has two red cell populations, one of the rhesus genotype rr, and the other R1r. Further studies showed that she has two populations of lymphocytes, one with the female karyotye, 46XX, and the other with the male karyotype, 46XY. Skin fibroblasts were all 46XX.
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  • 20
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The red cells of a normal male blood donor, K.S., were first grouped as B but he was found to lack anti-A in his serum. Closer investigation revealed that his red cells had very weak A activity, demonstrable only by absorption and elution of anti-A. He is a non-secretor of ABH and a secretor of Lea. Blood group A-, B and H-gene specified glycosyltransferases were detected in his serum. In contrast to the finding of a B antigen of normal strength on his red cells, the B transferase in his serum was only about 30% of the normal level and, despite the very weak A activity of K.S.'s red cells, the A transferase level was about 50% of that found in the serum of group A individuals with normal strength of A antigen. Moreover, the A transferase on the basis of its pH optimum, Km values for donor and acceptor substrates, activation by divalent cations, isoelectric focusing profile and capacity to convert O to A-active cells, was characterized as the product of an A1 gene. A family study showed that K.S.'s wife is group A2 and that they have two sons, one group A2 and the other group B. The group B son is assumed to have inherited a B gene from the propositus but the level of B transferase in the son's serum is three times as high as that in his father's serum. The wife of the propositus and his group A2 son have normal A2 transferases in keeping with their A2 red cell status. The A2 son therefore appears to have inherited an A2 gene from his mother but neither the A1 nor the B gene shown to be carried by his father. The distribution of transferase activities in K.S.'s red cells differs from that in his serum. A level of B transferase within the normal range was found in his red cell membranes but a very low level of A transferase was detected. The discrepancies between the serum transferases and ABO-red cell group, together with the pattern of inheritance within the family, led to a suspicion of chimaerism. This was confirmed by the finding of fibroblasts with the female 46XX karyotype in cultures of the propositus' skin. These results suggest that K.S. is a dispermic chimaera with two different cell lines of the genotypes BO and A1O or A1A1. The group A2 son is assumed to have inherited an O gene from his father. It seems probable that K.S.'s bone marrow and reproductive organs are comprised predominantly of the XY cell line which carries the blood group BO genotype whereas his skin and other tissues which contribute the A1 transferase to his plasma, are partly made up of the XX cell line which carries the blood group A1O or A1A1 genotype.
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