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  • Articles  (4)
  • Articles: DFG German National Licenses  (4)
  • Archimantis brunneriana  (2)
  • histamine antagonists  (2)
  • Medicine  (4)
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  • Articles  (4)
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  • Articles: DFG German National Licenses  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    The H1-antagonist mequitazine: Studies on performance and visual function (1983)
    Springer
    European journal of clinical pharmacology 25 (1983), S. 563-566 
    Details
    ISSN: 1432-1041
    Keywords: histamine antagonists ; psychomotor performance ; terfenadine ; triprolidine ; mequitazine ; subjective feeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of single oral doses of mequitazine (5 and 10 mg), terfenadine (60 mg) and triprolidine (10 mg) as active controls, and placebo were evaluated on visuo-motor coordination, digit symbol substitution, critical flicker fusion and dynamic visual acuity, and on subjective assessments of mood and well-being in six normal female volunteers. The study was double-blind. Mequitazine (5 mg) impaired visuo-motor coordination 7.5 h after ingestion (considered to be a chance result), but there was no effect on digit symbol substitution, critical flicker fusion threshold or dynamic visual acuity. Mequitazine (10 mg) impaired visuo-motor coordination and reduced the number of substitutions on the digit symbol substitution test. Terfenadine (60 mg) had no effect on performance or on subjective feelings. Triprolidine (10 mg) impaired visuo-motor coordination, reduced the number of substitutions on the digit symbol test, lowered the critical flicker fusion threshold and reduced dynamic visual acuity. Mequitazine (5 mg) and terfenadine (60 mg) are likely to prove acceptable H1 antagonists when sedation must be avoided.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00542129
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Antihistamines: Impaired performance and the tendency to sleep (1986)
    Springer
    European journal of clinical pharmacology 30 (1986), S. 27-32 
    Details
    ISSN: 1432-1041
    Keywords: histamine antagonists ; sedation ; performance ; multiple sleep latencies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The central effects of various antihistamines were studied using a variety of tests of performance, including visuo-motor co-ordination and dynamic visual acuity, as well as paper and pencil tests and critical flicker fusion. The possible relationship between performance and sedation was also studied using digit symbol substitution and latencies to drowsy sleep. There was high degree of correlation between drowsiness, as indicated by the relative ease with which individuals fell asleep over the day, and impaired performance, but it was not possible to establish the relationship for each time of the day. These findings lend some support to the suggestion that impaired performance with antihistamines may be a non-specific effect of sedation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00614191
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The cercal receptor system of the praying mantid, Archimantis brunneriana Sauss. (1982)
    Springer
    Cell & tissue research 224 (1982), S. 55-70 
    Details
    ISSN: 1432-0878
    Keywords: Praying mantid ; Cerci ; Insect sensilla ; Trichoid sensilla ; Filiform sensilla ; Archimantis brunneriana
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The cerci of the praying mantid, Archimantis brunneriana Sauss., are paired segmented sensory organs located at the tip of the abdomen. Basally the cercal segments are slightly flattened dorso-ventrally and are fused to such a degree that it is difficult to distinguish them. Distally the segments become progressively more flattened laterally and their boundaries become more obvious. Two types of sensilla are present on the cerci, trichoid sensilla and filiform sensilla. Trichoid hairs are longest on the medial side of the cerci and toward the cercal base. On the proximal cercal segments they are grouped toward the middle of each segment while they are more uniformly distributed on the distal segments. Filiform sensilla are found at the distal end of each segment except the last and are most abundant on the middle segments of the cercus. Both the number of cercal segments and the number of sensilla are variable. Trichoid hairs are highly variable in appearance from short and stout to long and thin. They arise from a raised base, have a fluted shaft, and some have a pore at the tip. They are innervated by from one to five dendrites, one of which is always considerably larger than the others. Some of the dendrites continue out into the shaft of the hair. Filiform hairs have fluted shafts and are mounted in a flexible membrane within a cuticular ring in a depression. They are innervated by a single large sensory neuron, the dendrite of which passes across a flattened area on the inner wall of the lumen of the hair. The dendritic sheath forms the lining of the ecdysial canal and is therefore firmly attached to the hair. The dendrite is attached to the sheath by desmosomes distally and is penetrated by projections of the sheath more proximally. A fibrous cap surrounds the dendrite and may hold it in place relative to the hair. The cercal receptor system of Archimantis is compared to those of cockroaches and crickets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217266
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  • 4
    Electronic Resource
    Electronic Resource
    The cercal receptor system of the praying mantid, Archimantis brunneriana Sauss. (1982)
    Springer
    Cell & tissue research 224 (1982), S. 71-80 
    Details
    ISSN: 1432-0878
    Keywords: Praying mantid ; Cerci ; Filiform sensilla ; Archimantis brunneriana
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The bilaterally paired cereal nerves of Archimantis brunneriana Sauss. leave the terminal ganglion posteriorly and then turn dorsally through muscles at the rear of the abdomen to enter the cerci, where each splits into two branches; successive branchings occur further distally in each cercus. In the distal nerve branches large axons tend to be grouped together. The cereal nerves are heavily wrapped in glial sheaths. Cobalt backfills of the cercal nerve reveal a projection which enters the ganglion at approximately 30° to the midline and then turns parallel to it. Most of the projection remains ipsilateral but bundles of axons approach or cross the midline in 6–8 places. At the anterior end of the ganglion there are strong projections both laterally and medially. In the posterior half of the ganglion fibers run ventrally to surround two glomeruli and there is a dorsal projection in the anterior half of the ganglion. There is a strong projection anteriorly into the ventral nerve cord. The electrophysiological responses of single cercal receptors to pulses of wind were recorded in the cercal nerve or terminal ganglion. These receptors, presumed to innervate filiform hairs, were then filled with Lucifer Yellow. All had ipsilateral projections. Most receptors showed little adaptation to stimuli as long as 5 seconds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217267
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    Paper (German National Licenses)
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