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  • Articles  (73)
  • Articles: DFG German National Licenses  (73)
  • Cell & Developmental Biology  (73)
  • 1965-1969  (73)
  • 11
    Electronic Resource
    Electronic Resource
    Cellular organization and ferritin uptake in the mid-gut epithelium of a moth, Ephestia kühniellaThe work described in this paper was carried out during a graduate course in Cell Biology, conducted in Spring 1966 by the senior author, in the Biology Department, University of Virginia. (1969)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 127 (1969), S. 41-71 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The fine structure of the mid-gut epithelium and regenerative cells of larvae of a moth (Ephestia kühniella) is described. Particular attention is paid to the absorptive and goblet cells and their lateral junctions; these features are discussed in terms of the digestive and regulatory functions of the epithelium. One digestive pathway has been investigated with the aid of ingested ferritin; intake of this marker by endocytosis and the evident involvement of Golgi vesicles in the transformation of endocytic vesicles into multivesicular bodies, together with the fate of the latter, are discussed in terms of the digestive function of this part of the alimentary tract and of the lysosome concept.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051270104
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  • 12
    Electronic Resource
    Electronic Resource
    Tissue dynamics of steady state growth in Hydra littoralis. II. Patterns of tissue movement (1967)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 121 (1967), S. 19-28 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In the column of hydra, tissues continually move away from a region located just underthe whorl of tentacles. Above this subtentacular region, tissues proceed into the hypostome and tentacles; below it tissues pass into the buds or continue down the stalk. These movements represent a steady state pattern of tissue renewal in which column growth is balanced by tissue loss at the body extremities. But the existence of a subtentacular zone in which tissue appears stationary does not necessarily indicate that growth is restrictedto this region, as is commonly stated.The body column of hydra can be viewed as an expanding cylinder whose elongation is balanced by tissue loss at the two ends. In such a body there must be one region from whichtissue appears to emanate, regardless of how growth is distributed along the cylinder. Only the rates at which tissues move will be characteristic of the underlying growthpattern. In Hydra littoralis, the measured rates of tissue movement down the gastric column are consistent with the distributions of mitotic figures, which indicate that growth is spread out along the column.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051210103
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  • 13
    Electronic Resource
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    Oxytalan fibers in the periodontal ligament of the Caiman and the Alligator (Crocodilia, Reptilia) (1967)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 122 (1967), S. 169-173 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Histological examination of the fibrous and cellular connective tissue components of the periodontal ligament in the Caiman and the Alligator reveals the presence of reticular fibrillae, collagenic, elastic, and oxytalan fibers, as well as fibrocytes, osteoblasts, cementoblasts and epithelial rests. The oxytalan fibers differentiated by the peracetic acid aldehyde-fuchsin method are most numerous in the coronal region, radiating from the primary cementum into the periodontal ligament a short distance. Oxytalan fibers in fewer numbers are found interspersed between the oblique and the horizontal principal fiber bundles. Inasmuch as the crocodilian teeth have continuous replacement and thus a relatively short functional life, the oxytalan fibers of the Caiman and the Alligator appear to be proportionally fewer in number than they are in the mammalian periodontal tissues. The presence of the oxytalan fibers and epithelial rests in the Order Crocodilia (Crocodilia) adds to the number of dental structures shared with the Class Mammalia (Mammalia) (mammals) such as a stellate reticulum, a primary and secondary cementum and a periodontal ligament. This furnishes additional histological evidence for evaluation of the phylogenetic position of this group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051220302
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  • 14
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    Cytoplasmic filaments and associated lucké viruses in the frog renal adenocarcinomaSupported in part by research grant (CA 07048) from the United States Public Health Seervice and by a University of Delaware Research Foundation grant. (1967)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 123 (1967), S. 63-69 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The morphology and possible functional significance of cytoplasmic filaments associated with herpes-like viruses of the frog renal carcinoma is described. Filaments, invariability arranged in elongated bundles or sheaths, individually measure approximately 30 mμ in diameter, and are composed of finely granular, proteinaceous material. During the viral maturation sequence, this material is believed to be deposited on the surface of the capsid, thereby possibly providing the virus with a defensive coating prior to ergression from the cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051230106
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  • 15
    Electronic Resource
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    A histological study of non-follicular cysts in the ovulation fossa region of the equine ovary (1968)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 124 (1968), S. 313-320 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Forty-two unselected ovaries from adult mares were examined histologically, and with histochemical methods for mucins. A considerable part of the surface of the ovulation fossa was directly covered by columnar epithelium, with many ciliated cells. This epithelium, which was distributed mainly on the anterior side of the ovulation fossa, closely resembled the contiguous epithelium of the infundibulum of the oviduct, was frequently folded, and gave rise to short clefts projecting into the ovarian substance. The remainder of the ovulation fossa was covered by non-ciliated, low cuboidal or squamous epithelium, lacking folds or clefts.“Fossa cysts,” up to 6.5 mm in diameter, were observed in the ovarian tissue around the ovulation fossa in 27 (64%) of these ovaries. Both simple and branched, tubular and vesicular forms were present, and all were blind-ending. Their epithelial lining cells, which varied from simple squamous to columnar in type, were frequently ciliated. Many fossa cysts contained secretions histochemically similar to those of the columnar epithelium of the ovulation fossa and infundibulum. Both sialic acidcontaining and neutral mucins were present. It is suggested that these cysts were probably derived by ingrowth from the columnar epithelium of the ovulation fossa. This epithelium may be of müllerian duct origin.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051240305
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  • 16
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    Histochemistry of the “sexual segment” granules of the male rattlesnake kidneyThis investigation was supported by grant AM-06867-1 from the National Institutes of Health, Public Health Service. (1965)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 116 (1965), S. 189-195 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The histochemistry of the “sexual segment” granules of the kidney of male diamondback rattlesnakes has been studied to define the nature of these andro-genically responsive granules. The kidneys were variously fixed and sections stained with a number of acid dyes, as well as by a variety of carbohydrate, lipid, and protein histochemical methods. The results indicate that “sexual segment” granules bind acid dyes strongly, contain some lipids and neutral glyco- or mucoproteins, much tyrosine and lysine, and some tryptophan and cysteine. A resemblance, concluded to be superficial, is noted between the histochemical properties of zymogen granules and the predominantly proteinaceous “sexual segment” granules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051160204
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  • 17
    Electronic Resource
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    Ultrastructure of human labial salivary glands. I. Acinar secretory cells (1969)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 127 (1969), S. 383-407 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The structure of human labial salivary gland acini was studied by light and electron microscopy. Contrary to previous reports, these glands were pure mucous in nature; no serous elements were present. The acinar cells were found in all stages of maturation. Immature cells were characterized by an extensive and highly organized rough-surfaced endoplasmic reticulum. The Golgi complex was extremely prominent, consisting of stacks of flattened cisternae and swarms of small vesicles. Mucous droplets were almost completely absent. As secretory activity progressed, the endoplasmic reticulum involuted, while the Golgi cisternae became distended and formed many vacuoles. In mature mucous cells, the apical cytoplasm was filled with membrane-bounded mucous droplets, and the nucleus was displaced basally. The droplets frequently showed great variation in density from cell to cell, and even within the same cell they sometimes were quite heterogeneous. They were liberated from the acinar cells by an apocrine process, so that droplets with intact limiting membranes were often observed in the acinar lumen. These droplets soon lysed, their contents fusing into streams of mucus. Occasionally during apocrine secretion a mucous cell failed to reconstitute its apical surface, and its entire contents spilled into the acinar lumen.Unusual cytoplasmic inclusions were present in many of the acinar cells. These inclusions, which were surrounded by a single membrane, consisted of lipid droplets closely associated with bundles of fine filaments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051270402
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  • 18
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    The development of the ovary of the sea lamprey (Petromyzon marinus L.)This investigation was supported by a research grant from the National Research Council of Canada. (1965)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 117 (1965), S. 425-466 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This investigation is a histological study of the development of the ovary of the sea lamprey from south-western Ontario, Canada. Development is described from the first appearance of primordial oögonia at the site of the ovary up to ovulation. After mitotic proliferation, oögonia enter meiotic prophase and become oöcytes which enlarge and acquire basophilic cytoplasm.During metamorphosis all oöcytes are at a uniform stage of development and no oögonia remain in the ovary.The follicular layer in the early adult produces nurse cells which are incorporated into the oöcyte and increase its mass of RNA-rich cytoplasm. As the oöcyte enlarges, proteid yolk platelets are laid down in the cytoplasm. Vacuolation of the nucleolus, indicative of protein synthesis, is extensive during period of rapid growth and yolk formation.Immediately prior to spawning there is an accumulation of fluid under the follicular layer and the oöcyte emerges through a mound of follicular cells.Atresia of oöcytes occurs throughout the adult stages and following spawning. It is characterized by an enzymic dissolution of the yolk followed by phagocytic invasion. The phagocytes arise from the follicle in the early adult stages and from an unidentified source in the spawning-phase adult.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051170307
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  • 19
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    A new intranuclear inclusion body in the frog renal adenocarcinomaThis investigation was supported in part by a research grant (CA 07048) from the National Institutes of Health, Public Health Service, Bethesda, Maryland. (1966)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 118 (1966), S. 581-587 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The morphology and possible functional significance of a new intranuclear inclusion body associated with the frog renal adenocarcinoma is described. The inclusion consists of particles, 40 to 50 mμ in diameter, arranged in an orderly pattern suggestive of a crystalline array. Individual particles eventually appear to be involved in the production of “doughnut” type virions characteristically associated with this malignancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051180410
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  • 20
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    Histochemical observations on mucin secretion by subsurface epithelial structures in the canine ovary (1966)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 120 (1966), S. 347-358 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Histochemical methods for mucins were applied to the ovaries of 23 dogs.Solid and hollow groups and cords of epithelial cells (subsurface epithelial structures, SES) in the outer part of the cortex regularly showed evidence of mucin secretion. Intracytoplasmic, sialic acid-containing, acid mucin secretion droplets were seen in solid and hollow SES, and secretion was present in both closed lumina and those opening onto the surface.Intracytoplasmic droplets in the cells of SES were distinctive, and similar droplets were not found in the cells of any other ovarian epithelial component. The secretion of SES was not shown to possess distinctive histochemical features.Mucin production was also observed in follicles, corpora lutea and rete tubules.The significance of ingrowth from the ovarian surface epithelium in adult life, and of secretory activity by the cells of SES, are discussed.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051200403
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