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The effects of X-irradiation on mammalian oocytes in organ culture (1969)

Baker, T. G. ; Neal, P.

Springer

Radiation and environmental biophysics 6 (1969), S. 39-45

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ISSN: 1432-2099

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Physics

Notes: Summary A technique for maintaining mammalian ovaries in organ culture is described. Ovaries of rats, mice, monkeys and humans have been maintained in a histologically normal condition for up to 20 days in culture, during which many were X-irradiated. The doses of X-rays required to destroy all the primordial oocytes in organ cultures are similar to those reported forin vivo studies. The human foetal ovary is resistant to X-irradiation. Some oocytes survive for 7 days following exposure to 4000 R in organ culture. The radiation sensitivity of the human ovary is discussed: it would appear that it is amongst the most resistant to oocyte-killing known.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01403867

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