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  • Articles  (5)
  • Articles: DFG German National Licenses  (5)
  • Springer  (5)
  • 1990-1994  (4)
  • 1985-1989  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Nucleotide sequence of the humanθ 1-globin gene (1988)
    Springer
    Biochemical genetics 26 (1988), S. 207-211 
    Details
    ISSN: 1573-4927
    Keywords: DNA sequence ; human θ1-globin gene ; cloning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract We have cloned and sequenced the human θ1-globin gene. The nucleotide sequence and organization of the human θ1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan θ1-globin gene. If these genes are functional, the sequences of their θ1-globin chains would differ by only one amino acid residue (at position 137).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00561460
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Structural shape optimization integrated with CAD environment (1990)
    Springer
    Structural and multidisciplinary optimization 2 (1990), S. 23-28 
    Details
    ISSN: 1615-1488
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The research work presented here is based on the concept of the integration of optimization techniques and numerical analysis with the finite element method (FEM) and computer-aided design (CAD). A microcomputer aided optimum design system, MCADS, has been developed for general structures. Certain techniques to be discussed in the paper, e.g. the semi-analytical method for design sensitivity analysis, optimization analysis modelling for shape design, application oriented user interfaces and the coupling of automated optimization and user intervention have rendered MCADS pratical and versatile in applications for engineering structures. The above techniques and an application are presented in this paper.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01743517
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  • 3
    Electronic Resource
    Electronic Resource
    Structural modelling and sensitivity analysis of shape optimization (1993)
    Springer
    Structural and multidisciplinary optimization 6 (1993), S. 29-37 
    Details
    ISSN: 1615-1488
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract It is presented in this paper that the structural modelling of shape optimization is composed of, in general cases, four distinct processes on geometry, design, analysis and perturbation models. The relationships between these models are discussed. An integrated modelling approach based on geometric shape parameterization and automatic mesh generation is proposed. In cooperation with this modelling approach, the semi-analytic sensitivity analysis has been effectively employed. These techniques join shape optimization with FEM and CAD packages and apply it versatilely to optimum designs of general structures. The implementation and applications of the integrated modelling approach and semi-analytic sensitivity analysis to shape optimization of structures with coupling of stress and temperature fields are illustrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01743172
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  • 4
    Electronic Resource
    Electronic Resource
    In vitro uptake and autoradiographic localization of tritiated gossypol inTaenia taeniaeformis metacestodes (1993)
    Springer
    Parasitology research 79 (1993), S. 279-285 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Gossypol, a natural polyphenolic compound, induces growth-inhibitory and antiparasitic effects inTaenia taeniaeformis metacestodes in vivo and in vitro. We investigated the uptake and localization of [3H]-gossypol in this parasite. Metacestodes were incubated in 10−5 M [3H]-gossypol at 37°C. Parasites steadily took up tritium activity over the first 3 h of incubation, after which a plateau was maintained for the duration of the experiment. Tissue: medium radioactivity ratios revealed that intralarval tritium activity matched extralarval activity within 30 min of incubation and continued to increase with time. Reverse-phase high-performance liquid chromatographic (HPLC) analysis confirmed tissue incorporation of tritium activity that manifested as a single radioactive species. Autoradiography localized [3H]-gossypol to the tegument, calcareous corpuscles, and parenchyma over the first 2 h of incubation. By 6 h, parenchymal radioactivity had disappeared.T. taeniaeformis metacestodes rapidly take up and accumulate [3H]-gossypol in vitro. This accumulation is apparently selective for specific sites, which may have implications for gossypol's metacestocidal action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00932182
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  • 5
    Electronic Resource
    Electronic Resource
    Genetic mapping of the gene encoding guanylate cyclase-A/atrial natriuretic factor receptor (Npra) to mouse Chromosome 3 (1994)
    Springer
    Mammalian genome 5 (1994), S. 520-522 
    Details
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00369325
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