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Sequence of swallow, a gene required for the localization of bicoid message in Drosophila eggs (1991)

Chao, Yu-Chan ; Donahue, Kathleen M. ; Pokrywka, Nancy J. ; [et al.]

Chichester [u.a.] : Wiley-Blackwell

Developmental Genetics 12 (1991), S. 333-341

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ISSN: 0192-253X

Keywords: Maternal effect gene ; DNA sequencing ; protein ; Life and Medical Sciences ; Genetics

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology

Notes: We report the sequence of the Drosophila maternal effect gene swallow, one of the genes whose product is required for the localization of bicoid message during Drosophila oo-genesis. The inferred swallow protein contains a domain that is predicted to be an amphipathic α-helix similar to those implicated in protein:protein associations in other systems. Another part of the predicted protein appears to be a diverged RNA-binding motif. We discuss these structural features in light of the function of the swallow protein in the bicoid message localization process.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/dvg.1020120502

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