Publication Date:
2009-01-01
Description:
A simple, green and efficient solventless procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones (and -thiones) from aldehydes, β-ketoesters and urea or thiourea in the presence of catalytic amount of silica-supported P2O5(P2O5/SiO2) at 85 °C is described. Using this method, the title compounds were produced in high yields.
Electronic ISSN:
0973-4945
Topics:
Chemistry and Pharmacology
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