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  • Springer  (349)
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  • 1
    Electronic Resource
    Electronic Resource
    A new polymorphism of arylsulfatase A within the coding region (1996)
    Springer
    Human genetics 〈Berlin〉 98 (1996), S. 348-350 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A 10-year-old boy with juvenile metachromatic leukodystrophy (MLD) presented with the 459 + 1G→A arylsulfatase A (ASA) mutation on one allele. To detect his complete genotype, the other ASA allele was sequenced and a T-to-C transition at nucleotide 376 in exon 2 was identified. This missense mutation results in a substitution of leucine 76 by proline. Of 20 MLD unrelated controls, 18 carried the L/P76 mutation either in the homozygous (n = 6) or heterozygous (n = 12) state. The presence or absence of L/P76 did not influence leukocyte ASA activity or urinary sulfatide excretion. Apparently, the substitution of leucine 76 by proline is a common ASA polymorphism, neither being related to MLD nor creating ASA pseudodeficiency. However, because of its frequency and location, L/P76 may be of particular importance in genetic studies requiring the differentiation of the ASA alleles within a kindred. Further studies are directed to the as yet unresolved genotype of the index case with juvenile MLD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390050221
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  • 2
    Electronic Resource
    Electronic Resource
    Measurement of laser light thomson-scattered from a cooling electron beam (1987)
    Springer
    Applied physics 44 (1987), S. 87-92 
    Details
    ISSN: 1432-0649
    Keywords: 41.80E ; 52.25 ; 29.15D
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract First results are presented from an experiment scattering laser light from a relativistic electron beam. The 5 cm diameter continuous electron beam of 28 keV kinetic energy and 2.6 A current presents an electron gas of a density of 8×107 cm−3, from which 20 ns pulses of laser light (490 nm) were scattered at a repetition rate of 15 Hz and an average power of 20 mJ per pulse. The Doppler-shifted wavelength of photons backscattered under 180° was analysed with a Fabry-Perot interferometer. This technique provides, for the first time, a non-destructive measurement of the velocity distribution in an electron beam radially resolved in space. The results presented here comprise the direct measurement of the absolute electron energy and the degree of space-charge compensation in the electron beam. The determination of an upper bound of 10−2 for the ratio of longitudinal to transverse electron temperature implies the first direct measurement of a flattened velocity distribution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00694198
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  • 3
    Electronic Resource
    Electronic Resource
    Der Bau stabilisierter Waldstraßen (1954)
    Springer
    European journal of forest research 73 (1954), S. 329-349 
    Details
    ISSN: 1612-4677
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01819028
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  • 4
    Electronic Resource
    Electronic Resource
    Antibiotics X-948 and X-1008 (1957)
    Springer
    Cellular and molecular life sciences 13 (1957), S. 434-436 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es werden zwei neue, chemisch verwandte Streptomyces Antibiotika beschrieben, X-948 (C29H39O7N7S ?) und X-1008 (C29H38O7N6S ?). X-948 ist wahrscheinlich identisch mit Echinomycin. Es hat sehr ähnliche physikalische Eigenschaften und gibt die gleichen Abbauprodukte (Ammoniak, 2-Chinoxalincarbonsäure, N-Methyl-l-valin,l-Alanin undd-Serin).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02157235
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  • 5
    Electronic Resource
    Electronic Resource
    Zellmorphologische Veränderungen im Vaginalabstrich nach Strahleneinwirkung (1967)
    Springer
    Cellular and molecular life sciences 23 (1967), S. 879-883 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary (1) The vaginal smears show no definite criteria of susceptibility to radiation except for the disappearance of the atypical cells. (2) Nothing can be said about the diagnosis. Only the clinical status may enable the experienced gynaecologist to predict the prognosis. (3) The cytology of the vagina serves as an important guide to the progress of cases of carcinoma which had been radiated or operated. The diagnosis of recurrence of the local, highly differentiated carcinoma, following radiation may present difficulties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02146909
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  • 6
    Electronic Resource
    Electronic Resource
    Green's function for steady-state heat conduction in a bimaterial composite solid (2000)
    Springer
    Computational mechanics 25 (2000), S. 627-634 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The derivation of a Green's function for steady-state heat conduction in anisotropic bimaterials is presented. The Green's function is obtained through a Fourier representation to obtain both free-space, singular parts and region-dependent, regular parts. To obtain the region-dependent parts of the Green's function, the homogeneous solution is written using the virtual force method. Full details of the necessary inversion integrals are provided. The Green's function is shown to degenerate to the usual logarithmic potential for steady-state heat conduction in isotropic solids. The normal derivatives necessary for implementation of the Green's function in boundary integral equations are provided, and an example calculation of the Green's function in a quartz-copper material system is presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660050509
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  • 7
    Electronic Resource
    Electronic Resource
    Boundary integral equation formulation for Interface cracks in anisotropic materials (1997)
    Springer
    Computational mechanics 20 (1997), S. 261-266 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract We present a boundary integral formulation for anisotropic interface crack problems based on an exact Green's function. The fundamental displacement and traction solutions needed for the boundary integral equations are obtained from the Green's function. The traction-free boundary conditions on the crack faces are satisfied exactly with the Green's function so no discretization of the crack surfaces is necessary. The analytic forms of the interface crack displacement and stress fields are contained in the exact Green's function thereby offering advantage over modeling strategies for the crack. The Green's function contains both the inverse square root and oscillatory singularities associated with the elastic, anisotropic interface crack problem. The integral equations for a boundary element analysis are presented and an example problem given for interface cracking in a copper-nickel bimaterial.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660050246
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  • 8
    Electronic Resource
    Electronic Resource
    Driving traction on phase boundary interfaces in solids with boundary elements (1998)
    Springer
    Computational mechanics 22 (1998), S. 19-25 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A method of computing driving tractions for phase transformations is presented. The driving traction calculation requires evaluating the jump in the displacement gradient and the average stress acting across the interface. A bimaterial Green's function is used in a boundary element formulation for the calculation. The Green's function satisfies all interface boundary conditions for the bimaterial providing an efficient formulation for evaluating the necessary jump and average interface terms. We derive a boundary integral equation for calculating the driving traction and apply the developed numerical tool to driving traction calculations in copper-aluminum-nickel.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660050334
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  • 9
    Electronic Resource
    Electronic Resource
    The negative correlation between erythrocyte concentration and mean corpuscular haemoglobin or mean corpuscular volume in normal dogs (1981)
    Springer
    Cellular and molecular life sciences 37 (1981), S. 906-907 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In normal adult Beagle dogs red cell concentration decreased linearly with increasing mean red cell volume and mean red cell haemoglobin. The results are statistically significant (p〈0.001).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01985707
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  • 10
    Electronic Resource
    Electronic Resource
    Identification of new enzyme activities of several strains of Thermus species (1995)
    Springer
    Applied microbiology and biotechnology 44 (1995), S. 81-87 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract  New thermostable enzyme activities of seven Thermus strains were compared using the API ZYM system. All the strains exhibited high levels of α- and β-glycosidases, esterase (C4) and esterase-lipase (C8) activities intracellularly. Only T. thermophilus HB8 (ATCC 27634) showed α-glucosidase and esterase activities in the supernatant. According to the intensity of β-galactosidase activity, Thermus strains were divided in three groups. Group 0, which showed a weak β-galactosidase activity, included Thermus spp. ATCC 31674 (T351) and 27978 (X-1) as well as T. thermophilus ATCC 27634 (HB8). Group I which consisted of T. aquaticus ATCC 25104 (YT-1), ATCC 25105 (Y-VII-51B) and Thermus sp. ATCC 27737 (T2), had a specific activity of approximately 40.0 U mg-1 and galactose as inducer. T. aquaticus ATCC 31558 (group 2) was particularly effective for β-galactosidase production (2840 U) with a specific activity of 98 U mg-1. For each strain, galactose (0.5%) was a better inducer of β-galactosidase production than lactose (1%). The detection of β-galactosidase activity was dependent on the derivative chromogenic substrates used (naphthyl or nitrophenol coupled to sugar). Oligosaccharides were synthesized from cellobiose, lactulose, maltose or lactose as substrates at high temperature in some strains of Thermus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002530050523
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