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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Advanced Materials for Optics and Electronics 8 (1998), S. 101-105 
    ISSN: 1057-9257
    Keywords: biosensor ; protein immobilisation ; protein modification ; electrochemistry ; nitrotyrosine ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Use of electrosynthetic methodology allows the production of hen egg-white lysozyme (HEWL) either mononitrated at tyrosine 23 or bisnitrated at tyrosines 20 and 23, but never nitrated at tyrosine 53. This is a different sequence from that obtained by the chemical nitrating agent tetranitromethane, and when reduced by dithionite, the selectively modified enzyme can be anchored at pH 5 via the unique aromatic amino group to magnetic beads or other suitable matrices. HEWL so immobilised loses less than 10% of cell-wall lytic activity compared with the approximately 50% loss of activity when immobilised by conventional methodology at pH 9 via essentially random reaction at lysine residues and other functionalities which are nucleophilic at this pH. This result offers promise as a general method for selective protein immobilisation in biosensors and similar applications. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 2
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    Am. Geophys. Union
    In:  Washington, D. C., Am. Geophys. Union, vol. 65, no. ALEX(01)-FR-77-01, AFTAC Contract F08606-76-C-0025, pp. 95-104, (ISBN: 0-08-044051-7)
    Publication Date: 1991
    Keywords: Textbook of geophysics ; Seismology ; Nuclear explosion
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  • 3
    Publication Date: 1971-05-01
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
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  • 4
    Publication Date: 2016-10-01
    Print ISSN: 2169-9380
    Electronic ISSN: 2169-9402
    Topics: Geosciences , Physics
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  • 5
    Publication Date: 2014-03-21
    Description: Standard processing of seismic events for reporting in bulletins is usually done one-at-a time. State-of-the-art relative event methods, often involving cross correlation, are increasingly used and have improved estimates of event parameters for event detection, location and magnitude. This is because relative event techniques can simultaneously reduce measurement error and effects of model error. We show how cross correlation can be used to assign relative magnitudes for neighbouring seismic events distributed over a large region in east Asia and quantify to what extent the uncertainty in these values increases as waveform similarity breaks down. We find that cross correlation works well for magnitude comparison of two events when it is expected that they generate very similar signals even if these may be almost buried in large amounts of noise. This may be the case when investigating repeating earthquakes or nuclear explosions within a few kilometres of each other. Cross correlation is the optimal detector in these cases assuming noise is white and Gaussian, and also provides the least-squares solution for the relative amplitudes. However, when the waveform similarity of the underlying signals breaks down, due to interevent separation distance, source time function differences or focal mechanism differences, these assumptions are no longer valid and a bias is introduced into the relative magnitude measurement. This bias due to degradation of waveform similarity is modelled here with synthetics and an analytic expression for it is derived based on three terms—the cross-correlation coefficient (CC), and the signal-to-noise ratio (SNR) of the larger and smaller events. The analytic expression is a good match to the observed bias in the data. If the equation for relative magnitude is rewritten to correct for the bias due to the CC, a new equation results which is simply the log of the ratio of the L2 norms. The bias due to SNRs is still present because the observed waveforms inevitably contain both signal and noise. However, this bias is predicted to be minimal for typical detection thresholds. Making measurements of the ratio of the L2 norms is shown to remove the bias due to degradation of waveform similarity for real data. The scatter of these cross-correlation measurements of relative magnitude is much less than those obtained by differencing magnitudes in a traditional catalogue. Of 14 025 events in and near China, 34 per cent had over an order of magnitude reduction in the median standard deviation (0.0342 magnitude units) as compared to the estimated scatter in the catalogue (0.3454 magnitude units). And 78 per cent of the events show a factor 3 improvement or better in the precision of relative event size measured as the ratio of the L2 norms as compared to the precision of the catalogue for relative magnitudes. These results suggest that the ratio of the L2 norms is an appropriate measure of relative magnitudes for general seismicity of a monitoring region, when there is significant waveform dissimilarity for neighbouring events. This measure maintains a higher degree of measurement precision as compared to the catalogue.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 6
    Publication Date: 2014-12-05
    Description: Waveform correlation is garnering attention as a method for detecting, locating, and characterizing similar seismic events. To explore the opportunities for using waveform correlation in broad regional monitoring, we applied the technique to a large region of central Asia over a three-year period, monitoring for events at regional distances using three high-quality stations. We discuss methods for choosing quality templates and introduce a method for choosing correlation detection thresholds, tailored for each template, for a desired false alarm rate. Our SeisCorr software found more than 10,000 detections during the three-year period using almost 2000 templates. We discuss and evaluate three methods of confirming detections: bulletin confirmation, high correlation with a template, and multistation validation. At each station, 65%–75% of our detections could be confirmed, most by multistation validation. We confirmed over 6500 unique detections. For monitoring applications, it is of interest that a significant portion of the Comprehensive Nuclear-Test-Ban Treaty Organization’s Late Event Bulletin (LEB) catalog events was detected and that adding our confirmed detections for the LEB catalog would more than double the catalog size. Waveform correlation also allows for relative magnitude calculation, and we explore the magnitudes of detected events. The results of our study suggest that doing broad regional monitoring using historical and real-time-generated templates is feasible and will increase detection capabilities.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
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  • 7
    Publication Date: 2017-02-03
    Description: We assess seismological evidence bearing on claims that North Korea conducted a small nuclear test on 12 May 2010 in the vicinity of known underground nuclear tests (UNTs) in 2006, 2009, 2013, and 2016. First, we use Lg -wave cross correlation and more traditional methods to locate the 2010 event between about 4 and 10 km southwest of the 2009 test. Second, we compare the relative sizes of regional P and S waves, using stations within 400 km of the known North Korean nuclear tests, to assess the nature of the event. We measured P / S ratios at different frequencies, at first using data from the open station MDJ in northeast China, for training sets of earthquakes and of explosions. We developed a linear discriminant function (LDF) that, in application to P / S measured at MDJ, is most effective in separating the earthquake and explosion populations. MDJ lacks usable data for the event of interest, but we obtained regional data from stations of the nearby Dongbei Broadband Seismographic Network (DBSN) for the 12 May 2010 event and for nearby UNTs conducted in 2006 and 2009. When our LDF is applied to DBSN data, and to data from stations SMT and NE3C in China, the LDF values measured from P / S ratios from known explosions are explosion-like; but for the 12 May 2010 event, the LDF values are earthquake-like for frequencies between 6 and 12 Hz. Our method for characterizing earthquakes and explosions on the basis of their regional signals can be widely applied. Measurements of P / S based on the three-component waveform data provide better discrimination power than do those based on vertical-component data alone. Electronic Supplement: Tutorial material on the Mahalanobis distance-squared measure, three-component linear discriminant function (LDF) analysis, tables of measurements of the log 10 P / S spectral ratios obtained from waveforms recorded at station MDJ for the two training sets and three-component discrimination analysis, and figures of log ( P / S ) values measured at 8 Hz from vertical-component waveforms at station MDJ for two training sets and probability distributions for D .
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
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  • 8
    Publication Date: 2018-02-12
    Description: This paper presents a comparison of modeled and measured electron densities for the 21 August 2017 solar eclipse across the USA. The location of the instrument was (43.81°N, 247.32°E) where the maximum obscuration of 99.6% occurred at 17.53 hr UT on 21 August. The solar apparent time was 9.96 hr, and the duration of the eclipse was 2.7 hr. It was found that if it is assumed that there are no chromosphere emissions at totality, ~30% coronal emission remaining at totality gave the best fit to the electron density variation at 150 km. The 30% coronal emission estimate has uncertainties associated with respect to uncertainties in the solar spectrum, the measured electron density, and the amount of chromosphere emissions remaining at totality. The agreement between the modeled and measured electron densities is excellent at 150 km with the assumed 30% coronal emission at totality. At other altitudes, the agreement is very good, but the altitude profile would be improved if the model peak electron density (NmF2) decayed more slowly to better match the data. The minimum NmF2 in the model occurs ~10 min after totality when it decreases to 0.55 from its noneclipse value. The minimum of the NmF2 data occurs between 6 and 10 min after totality but is ~15% larger. The total electron content decreases to 0.65 of its preeclipse value. These relative changes agree well with those predicted by others prior to the eclipse. ©2018. American Geophysical Union. All Rights Reserved.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
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  • 9
    Publication Date: 2018-08-28
    Description: This paper reports the results of ionosphere and plasmasphere observations with the Kharkiv incoherent scatter radar and ionosonde, Defense Meteorological Satellite Program, and Arase (ERG) satellites and simulations with field line interhemispheric plasma model during the equinoxes and solstices of solar minimum 24. The results reveal the need to increase NRLMSISE-00 thermospheric hydrogen density by a factor of ~2. For the first time, it is shown that the measured plasmaspheric density can be reproduced with doubled NRLMSISE-00 hydrogen density only. A factor of ~2 decrease of plasmaspheric density in deep inner magnetosphere (L ≈ 2.1) caused by very weak magnetic disturbance (D st  〉 −22 nT) of 24 December 2017 was observed in the morning of 25 December 2017. During the next night, prominent effects of partially depleted flux tube were observed in the topside ionosphere (~50% reduced H + ion density) and at the F2-layer peak (~50% decreased electron density). The likely physical mechanisms are discussed. ©2018. American Geophysical Union. All Rights Reserved.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
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  • 10
    Publication Date: 1990-05-01
    Print ISSN: 0084-6597
    Electronic ISSN: 1545-4495
    Topics: Geosciences , Physics
    Published by Annual Reviews
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