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  • 1
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    Chapman & Hall/CRC
    In:  Boca Raton, FL, Chapman & Hall/CRC, vol. 10, no. 1, pp. 1-40, (ISBN 1-58488-364-2)
    Publication Date: 2004
    Keywords: Textbook of mathematics ; Textbook of physics ; Modelling ; Data analysis / ~ processing ; software
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  • 2
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    In:  Geophysical Prospecting, Washington, D.C., AGU, vol. 32, no. 6B, pp. 871-891, pp. B01308, (ISSN: 1340-4202)
    Publication Date: 1984
    Keywords: Seismic stratigraphy
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  • 3
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    In:  Geophys. Pros, Kunming, China, D. Reidel Publishing Company, vol. 22, no. 30, pp. 627-651, pp. L09303, (ISSN: 1340-4202)
    Publication Date: 1974
    Keywords: Inversion
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  • 4
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    Chapman & Hall/CRC
    In:  Boca Raton, FL, 385 pp., Chapman & Hall/CRC, vol. 10, no. 1, pp. 1-40, (ISBN 1-58488-364-2)
    Publication Date: 2004
    Keywords: Handbook of mathematics
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  • 5
    Publication Date: 2012-08-23
    Description: Detailed analyses of the chromatin around the BIM promoter has revealed that latent Epstein–Barr virus (EBV) triggers the recruitment of polycomb repressive complex 2 (PRC2) core subunits and the trimethylation of histone H3 lysine 27 (H3K27me3) at this locus. The recruitment is absolutely dependent on nuclear proteins EBNA3A and EBNA3C; what is more, epitope-tagged EBNA3C could be shown bound near the transcription start site (TSS). EBV induces no consistent changes in the steady-state expression of PRC2 components, but lentivirus delivery of shRNAs against PRC2 and PRC1 subunits disrupted EBV repression of BIM . The activation mark H3K4me3 is largely unaltered at this locus irrespective of H3K27me3 status, suggesting the establishment of a ‘bivalent’ chromatin domain. Consistent with the ‘poised’ nature of these domains, RNA polymerase II (Pol II) occupancy was not altered by EBV at the BIM TSS, but analysis of phospho-serine 5 on Pol II indicated that EBNA3A and EBNA3C together inhibit initiation of BIM transcripts. B cell lines carrying EBV encoding a conditional EBNA3C-oestrogen receptor-fusion revealed that this epigenetic repression of BIM was reversible, but took more than 3 weeks from when EBNA3C was inactivated.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 6
    Publication Date: 2014-06-20
    Description: We investigate the effects of galaxy formation on the baryonic acoustic oscillation (BAO) peak by applying semi-analytic modelling techniques to the Millennium-XXL, a 3 10 11 particle N -body simulation of similar volume to the future Euclid survey. Our approach explicitly incorporates the effects of tidal fields and stochasticity on halo formation, as well as the presence of velocity bias, spatially correlated merger histories, and the connection of all these with the observable and physical properties of galaxies. We measure significant deviations in the shape of the BAO peak from the expectations of a linear bias model built on top of the non-linear dark matter distribution. We find that the galaxy correlation function shows an excess close to the maximum of the BAO peak ( r ~ 110 h –1 Mpc) and a deficit at r ~ 90 h –1 Mpc. Depending on the redshift, selection criteria and number density of the galaxy samples, these biased distortions can be up to 5 per cent in amplitude. They are, however, largely absorbed by marginalization over nuisance parameters in current analytical modelling of the BAO peak in configuration space, in particular into the parameter that controls the broadening due to non-linear evolution. As a result, the galaxy formation effects detected here are unlikely to bias the high-precision measurements planned by the upcoming generation of wide-field galaxy surveys.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 7
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2006-09-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Grossman, Richard A -- White, Richard E -- New York, N.Y. -- Science. 2006 Sep 29;313(5795):1886-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17008510" target="_blank"〉PubMed〈/a〉
    Keywords: *Birth Rate ; *Conservation of Natural Resources ; Economics ; Humans ; *Population Growth
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2016-03-14
    Description: We introduce methods which allow observed galaxy clustering to be used together with observed luminosity or stellar mass functions to constrain the physics of galaxy formation. We show how the projected two-point correlation function of galaxies in a large semi-analytic simulation can be estimated to better than ~10 per cent using only a very small subsample of the subhalo merger trees. This allows measured correlations to be used as constraints in a Monte Carlo Markov Chain exploration of the astrophysical and cosmological parameter space. An important part of our scheme is an analytic profile which captures the simulated satellite distribution extremely well out to several halo virial radii. This is essential to reproduce the correlation properties of the full simulation at intermediate separations. As a first application, we use low-redshift clustering and abundance measurements to constrain a recent version of the Munich semi-analytic model. The preferred values of most parameters are consistent with those found previously, with significantly improved constraints and somewhat shifted ‘best’ values for parameters that primarily affect spatial distributions. Our methods allow multi-epoch data on galaxy clustering and abundance to be used as joint constraints on galaxy formation. This may lead to significant constraints on cosmological parameters even after marginalizing over galaxy formation physics.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 9
    Publication Date: 2016-02-10
    Description: Mutations in genes encoding myosin, the molecular motor that powers cardiac muscle contraction, and its accessory protein, cardiac myosin binding protein C (cMyBP-C), are the two most common causes of hypertrophic cardiomyopathy (HCM). Recent studies established that the N-terminal domains (NTDs) of cMyBP-C (e.g., C0, C1, M, and C2) can...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 10
    Publication Date: 1996-10-25
    Description: The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. An international consortium was organized to develop and map gene-based sequence tagged site markers on a set of two radiation hybrid panels and a yeast artificial chromosome library. More than 16,000 human genes have been mapped relative to a framework map that contains about 1000 polymorphic genetic markers. The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease. The integrated resource is available through a site on the World Wide Web at http://www.ncbi.nlm.nih.gov/SCIENCE96/.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schuler, G D -- Boguski, M S -- Stewart, E A -- Stein, L D -- Gyapay, G -- Rice, K -- White, R E -- Rodriguez-Tome, P -- Aggarwal, A -- Bajorek, E -- Bentolila, S -- Birren, B B -- Butler, A -- Castle, A B -- Chiannilkulchai, N -- Chu, A -- Clee, C -- Cowles, S -- Day, P J -- Dibling, T -- Drouot, N -- Dunham, I -- Duprat, S -- East, C -- Edwards, C -- Fan, J B -- Fang, N -- Fizames, C -- Garrett, C -- Green, L -- Hadley, D -- Harris, M -- Harrison, P -- Brady, S -- Hicks, A -- Holloway, E -- Hui, L -- Hussain, S -- Louis-Dit-Sully, C -- Ma, J -- MacGilvery, A -- Mader, C -- Maratukulam, A -- Matise, T C -- McKusick, K B -- Morissette, J -- Mungall, A -- Muselet, D -- Nusbaum, H C -- Page, D C -- Peck, A -- Perkins, S -- Piercy, M -- Qin, F -- Quackenbush, J -- Ranby, S -- Reif, T -- Rozen, S -- Sanders, C -- She, X -- Silva, J -- Slonim, D K -- Soderlund, C -- Sun, W L -- Tabar, P -- Thangarajah, T -- Vega-Czarny, N -- Vollrath, D -- Voyticky, S -- Wilmer, T -- Wu, X -- Adams, M D -- Auffray, C -- Walter, N A -- Brandon, R -- Dehejia, A -- Goodfellow, P N -- Houlgatte, R -- Hudson, J R Jr -- Ide, S E -- Iorio, K R -- Lee, W Y -- Seki, N -- Nagase, T -- Ishikawa, K -- Nomura, N -- Phillips, C -- Polymeropoulos, M H -- Sandusky, M -- Schmitt, K -- Berry, R -- Swanson, K -- Torres, R -- Venter, J C -- Sikela, J M -- Beckmann, J S -- Weissenbach, J -- Myers, R M -- Cox, D R -- James, M R -- Bentley, D -- Deloukas, P -- Lander, E S -- Hudson, T J -- HG00098/HG/NHGRI NIH HHS/ -- HG00206/HG/NHGRI NIH HHS/ -- HG00835/HG/NHGRI NIH HHS/ -- Wellcome Trust/United Kingdom -- etc. -- New York, N.Y. -- Science. 1996 Oct 25;274(5287):540-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD 20894, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8849440" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Cell Line ; *Chromosome Mapping ; Chromosomes, Artificial, Yeast ; Computer Communication Networks ; DNA, Complementary/genetics ; Databases, Factual ; Gene Expression ; Genetic Markers ; *Genome, Human ; *Human Genome Project ; Humans ; Multigene Family ; RNA, Messenger/genetics ; Sequence Homology, Nucleic Acid ; Sequence Tagged Sites
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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