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  • 1
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    Preparation of Soluble Pertussis Vaccine (1964)
    Springer Nature
    Details
    Publication Date: 1964-08-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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    PAPER CURRENT
  • 2
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    Effects of noise upon human information processing (1974)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: Studies of noise effects upon human information processing are described which investigated whether or not effects of noise upon performance are dependent upon specific characteristics of noise stimulation and their interaction with task conditions. The difficulty of predicting noise effects was emphasized. Arousal theory was considered to have explanatory value in interpreting the findings of all the studies. Performance under noise was found to involve a psychophysiological cost, measured by vasoconstriction response, with the degree of response cost being related to scores on a noise annoyance sensitivity scale. Noise sensitive subjects showed a greater autonomic response under noise stimulation.
    Keywords: BIOTECHNOLOGY
    Type: NASA-CR-132469
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 3
    Electronic Resource
    Electronic Resource
    Preparation of Soluble Pertussis Vaccine (1964)
    [s.l.] : Nature Publishing Group
    Nature 203 (1964), S. 774-775 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Barta6, using sodium deoxycholate, has shown that such an approach is possible although a reproducible process for the treatment of large quantities of colls was not considered. The process we describe here is one by which a solution of the protective antigen can easily be obtained in sufficient ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/203774a0
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Vragen en antwoorden in de Tweede Kamer (1979)
    Springer
    Pharmacy world & science 1 (1979), S. 575-578 
    Details
    ISSN: 1573-739X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02293278
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Development of pertussis vaccine production and control in the National Institute of Public Health in the Netherlands during the years 1950–1962 (1963)
    Springer
    Antonie van Leeuwenhoek 29 (1963), S. 183-201 
    Details
    ISSN: 1572-9699
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The development of the pertussis vaccine production in the National Institute of Public Health in the Netherlands since 1953, and the results with the consecutive lots of vaccine in the mouse protection test and the U.S.A. toxicity test are described. The results in the latter test are compared with the results of a locally developed guinea pig toxicity test. Special attention is given to the difficulties encountered when the U.S.A. toxicity test is used for adsorbed DPT vaccines. The potency data of all lots of DPT vaccines produced since 1958 fall within the limits of the potency test as prescribed in the U.S.A. Minimum Requirements. There are indications that the increased potency of the vaccine may have led to a lower mortality rate of pertussis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02046052
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Quantitative complement fixation (1951)
    Springer
    Antonie van Leeuwenhoek 17 (1951), S. 247-258 
    Details
    ISSN: 1572-9699
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In agreement with the investigations ofKent et al. (4), it was found that blood collected in a modifiedAlsevers solution remains constant for a period of at least 14 days. We also succeeded in proving the same with regard to complement, stored according toRichardson (9) and with regard to amboceptor prepared according to the directions of the New York State Department of Health and stored in an equal volume of glycerol at 4° C. The cheap Eel colorimeter proved very suitable for the standardization of the erythrocyte-suspension and the measurement of the percentage of haemolysis. Success was not obtained by means of the method, used in this investigation, to keep the amount of complement, which under the conditions of the test causes haemolysis of 50% of erythrocytes, so constant, as to make daily complement titration unnecessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02062271
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  • 7
    Electronic Resource
    Electronic Resource
    An investigation about “anticoagulase”, a ferment said to be produced by staphylococci (1948)
    Springer
    Antonie van Leeuwenhoek 14 (1948), S. 87-96 
    Details
    ISSN: 1572-9699
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 2.75% K-oxalate human plasma was not coagulated below a pH 5.8–5.9, either by a CaCl2 solution, or by staphylo-coagulase. The prevention of plasma coagulation by the filtrate of a glucose broth culture of staphylococci must be ascribed to the decrease of pH. The experiments made byTillett (4) andTunnicliff andHammond (6) in studying the anticoagulation action of glucose broth cultures of streptococci are herewith confirmed. The neutralizing of the anticoagulating action of a filtrate of a glucose broth culture of staphylococci after treatment with kaolin must also be ascribed to an increase of pH caused by adsorption of acid metabolic products of the staphylococci. Staphylo-coagulase is not destroyed at pH 4.5.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02272682
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    Paper (German National Licenses)
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