Publication Date:
2018-05-09
Description:
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells, Published online: 08 May 2018; doi:10.1038/s41467-018-04134-7 It is unclear whether arterial specification is required for hematopoietic stem cell formation. Here, the authors use a chemically defined human pluripotent stem cell (hPSC) differentiation system to show the role of NOTCH signaling in forming arterial-type hemogenic endothelial cells.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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