ISSN:
0170-2041
Keywords:
Indolizines
;
Oxidative dimerisation, palladium-promoted
;
Cyclophanes
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Dimerisation of Indolizines by Palladium CoalOxidative dimerisation of some indolizines by Pd/C in p-xylene was undertaken in order to evaluate reaction conditions for cyclophane syntheses. Surprisingly, alkylation by the solvent occurred at the 3-position of the indolizines 2 and 5 as a side reaction. In toluene, yields of alkylation products 4b and 8 exceeded those of dimerisation products 3 and 6. The alkylation by the solvent was fully suppressed by using chlorobenzene or chlorotoluene. Alkylation products of indolizines with p-xylene or toluene and previously unknown dimeric indolizines are described.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199419941206
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