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Plastic ampoules for liquid smallpox vaccine (1962)

Espmark, Åke ; Lindner, Stig

New York, NY [u.a.] : Wiley-Blackwell

Biotechnology and Bioengineering 4 (1962), S. 323-330

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ISSN: 0006-3592

Keywords: Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: Manufacturing of plastic (PVC) single-dose ampoules for liquid smallpox vaccine is described. The green stained vaccine is injected in polyvinyl chloride tubes which are then sealed by high frequency welding to make ampoules of 16 mm. length. The tendency for desiccation of the filled vaccine at elevated temperature is considered as an advantage, since it provides a visible indication of previous improper storage. The ampoule is opened by cutting with scissors and vaccine is squeezed out directly on the skin.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bit.260040308

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