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  • 1
    Publication Date: 2012-09-05
    Description: Author(s): D. A. Hite, Y. Colombe, A. C. Wilson, K. R. Brown, U. Warring, R. Jördens, J. D. Jost, K. S. McKay, D. P. Pappas, D. Leibfried, and D. J. Wineland Motional heating of trapped atomic ions is a major obstacle to their use as quantum bits in a scalable quantum computer. The detailed physical origin of this heating is not well understood, but experimental evidence suggests that it is caused by electric-field noise emanating from the surface of the... [Phys. Rev. Lett. 109, 103001] Published Tue Sep 04, 2012
    Keywords: Atomic, Molecular, and Optical Physics
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 2
    Publication Date: 2011-09-15
    Description: Author(s): K. R. Brown, A. C. Wilson, Y. Colombe, C. Ospelkaus, A. M. Meier, E. Knill, D. Leibfried, and D. J. Wineland With a 9 Be + trapped-ion hyperfine-state qubit, we demonstrate an error probability per randomized single-qubit gate of 2.0(2)×10 −5 , below the threshold estimate of 10 −4 commonly considered sufficient for fault-tolerant quantum computing. The 9 Be + ion is trapped above a microfabricated surface-electr... [Phys. Rev. A 84, 030303] Published Wed Sep 14, 2011
    Keywords: Quantum information
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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  • 3
    Publication Date: 2008-09-27
    Description: Magnetars are young neutron stars with very strong magnetic fields of the order of 10(14)-10(15) G. They are detected in our Galaxy either as soft gamma-ray repeaters or anomalous X-ray pulsars. Soft gamma-ray repeaters are a rare type of gamma-ray transient sources that are occasionally detected as bursters in the high-energy sky. No optical counterpart to the gamma-ray flares or the quiescent source has yet been identified. Here we report multi-wavelength observations of a puzzling source, SWIFT J195509+261406. We detected more than 40 flaring episodes in the optical band over a time span of three days, and a faint infrared flare 11 days later, after which the source returned to quiescence. Our radio observations confirm a Galactic nature and establish a lower distance limit of approximately 3.7 kpc. We suggest that SWIFT J195509+261406 could be an isolated magnetar whose bursting activity has been detected at optical wavelengths, and for which the long-term X-ray emission is short-lived. In this case, a new manifestation of magnetar activity has been recorded and we can consider SWIFT J195509+261406 to be a link between the 'persistent' soft gamma-ray repeaters/anomalous X-ray pulsars and dim isolated neutron stars.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Castro-Tirado, A J -- de Ugarte Postigo, A -- Gorosabel, J -- Jelinek, M -- Fatkhullin, T A -- Sokolov, V V -- Ferrero, P -- Kann, D A -- Klose, S -- Sluse, D -- Bremer, M -- Winters, J M -- Nuernberger, D -- Perez-Ramirez, D -- Guerrero, M A -- French, J -- Melady, G -- Hanlon, L -- McBreen, B -- Leventis, K -- Markoff, S B -- Leon, S -- Kraus, A -- Aceituno, F J -- Cunniffe, R -- Kubanek, P -- Vitek, S -- Schulze, S -- Wilson, A C -- Hudec, R -- Durant, M -- Gonzalez-Perez, J M -- Shahbaz, T -- Guziy, S -- Pandey, S B -- Pavlenko, L -- Sonbas, E -- Trushkin, S A -- Bursov, N N -- Nizhelskij, N A -- Sanchez-Fernandez, C -- Sabau-Graziati, L -- England -- Nature. 2008 Sep 25;455(7212):506-9. doi: 10.1038/nature07328.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Instituto de Astrofisica de Andalucia del Consejo Superior de Investigaciones Cientificas (IAA-CSIC), PO Box 03004, E-18080 Granada, Spain. ajct@iaa.es〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18818652" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 1991-09-27
    Description: The proposal that all mitochondrial DNA (mtDNA) types in contemporary humans stem from a common ancestor present in an African population some 200,000 years ago has attracted much attention. To study this proposal further, two hypervariable segments of mtDNA were sequenced from 189 people of diverse geographic origin, including 121 native Africans. Geographic specificity was observed in that identical mtDNA types are shared within but not between populations. A tree relating these mtDNA sequences to one another and to a chimpanzee sequence has many deep branches leading exclusively to African mtDNAs. An African origin for human mtDNA is supported by two statistical tests. With the use of the chimpanzee and human sequences to calibrate the rate of mtDNA evolution, the age of the common human mtDNA ancestor is placed between 166,000 and 249,000 years. These results thus support and extend the African origin hypothesis of human mtDNA evolution.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vigilant, L -- Stoneking, M -- Harpending, H -- Hawkes, K -- Wilson, A C -- New York, N.Y. -- Science. 1991 Sep 27;253(5027):1503-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biochemistry and Molecular Biology, University of California, Berkeley 94720.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1840702" target="_blank"〉PubMed〈/a〉
    Keywords: Africa ; African Continental Ancestry Group/*genetics ; Animals ; *Biological Evolution ; DNA, Mitochondrial/*genetics ; Genome, Human ; Haplorhini/*genetics ; Humans ; Models, Genetic ; Restriction Mapping
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2011-02-25
    Description: The harmonic oscillator is one of the simplest physical systems but also one of the most fundamental. It is ubiquitous in nature, often serving as an approximation for a more complicated system or as a building block in larger models. Realizations of harmonic oscillators in the quantum regime include electromagnetic fields in a cavity and the mechanical modes of a trapped atom or macroscopic solid. Quantized interaction between two motional modes of an individual trapped ion has been achieved by coupling through optical fields, and entangled motion of two ions in separate locations has been accomplished indirectly through their internal states. However, direct controllable coupling between quantized mechanical oscillators held in separate locations has not been realized previously. Here we implement such coupling through the mutual Coulomb interaction of two ions held in trapping potentials separated by 40 mum (similar work is reported in a related paper). By tuning the confining wells into resonance, energy is exchanged between the ions at the quantum level, establishing that direct coherent motional coupling is possible for separately trapped ions. The system demonstrates a building block for quantum information processing and quantum simulation. More broadly, this work is a natural precursor to experiments in hybrid quantum systems, such as coupling a trapped ion to a quantized macroscopic mechanical or electrical oscillator.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, K R -- Ospelkaus, C -- Colombe, Y -- Wilson, A C -- Leibfried, D -- Wineland, D J -- England -- Nature. 2011 Mar 10;471(7337):196-9. doi: 10.1038/nature09721. Epub 2011 Feb 23.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Time and Frequency Division, National Institute of Standards and Technology, 325 Broadway, Boulder, Colorado 80305, USA. kenton.brown@nist.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21346762" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2014-08-08
    Description: Quantum simulation--the use of one quantum system to simulate a less controllable one--may provide an understanding of the many quantum systems which cannot be modelled using classical computers. Considerable progress in control and manipulation has been achieved for various quantum systems, but one of the remaining challenges is the implementation of scalable devices. In this regard, individual ions trapped in separate tunable potential wells are promising. Here we implement the basic features of this approach and demonstrate deterministic tuning of the Coulomb interaction between two ions, independently controlling their local wells. The scheme is suitable for emulating a range of spin-spin interactions, but to characterize the performance of our set-up we select one that entangles the internal states of the two ions with a fidelity of 0.82(1) (the digit in parentheses shows the standard error of the mean). Extension of this building block to a two-dimensional network, which is possible using ion-trap microfabrication processes, may provide a new quantum simulator architecture with broad flexibility in designing and scaling the arrangement of ions and their mutual interactions. To perform useful quantum simulations, including those of condensed-matter phenomena such as the fractional quantum Hall effect, an array of tens of ions might be sufficient.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, A C -- Colombe, Y -- Brown, K R -- Knill, E -- Leibfried, D -- Wineland, D J -- England -- Nature. 2014 Aug 7;512(7512):57-60. doi: 10.1038/nature13565.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Institute of Standards and Technology, 325 Broadway, Boulder, Colorado 80305, USA. ; Georgia Tech Research Institute, 400 10th Street Northwest, Atlanta, Georgia 30332, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25100480" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2016-09-03
    Description: Homing endonucleases are sequence-tolerant DNA endonucleases that act as mobile genetic elements. The ability of homing endonucleases to cleave substrates with multiple nucleotide substitutions suggests a high degree of adaptability in that changing or modulating cleavage preference would require relatively few amino acid substitutions. Here, using directed evolution experiments with the GIY-YIG homing endonuclease I-TevI that targets the thymidylate synthase gene of phage T4, we readily isolated variants that dramatically broadened I-TevI cleavage preference, as well as variants that fine-tuned cleavage preference. By combining substitutions, we observed an ~10 000-fold improvement in cleavage on some substrates not cleaved by the wild-type enzyme, correlating with a decrease in readout of information content at the cleavage site. Strikingly, we were able to change the cleavage preference of I-TevI to that of the isoschizomer I-BmoI which targets a different cleavage site in the thymidylate synthase gene, recapitulating the evolution of cleavage preference in this family of homing endonucleases. Our results define a strategy to isolate GIY-YIG nuclease domains with distinct cleavage preferences, and provide insight into how homing endonucleases may escape a dead-end life cycle in a population of saturated target sites by promoting transposition to different target sites.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 8
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-06-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carlson, S S -- Wilson, A C -- Maxson, R D -- New York, N.Y. -- Science. 1978 Jun 9;200(4346):1183-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17745110" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-04-14
    Description: The body shapes of humans and chimpanzees were compared quantitatively by criteria chosen for their capacity to discriminate well among the body shapes of frogs. By these criteria, the difference in body shape between humans and chimpanzees was found to be greater than that between the most dissimilar pairs of frogs examined--that is, frogs classified in separate taxonomic suborders. Even though the morphological diffference between the two primates is large by frog standards, the biochemical differences between the structural genes of these two species are small. The results of this study give quantitative support to the proposal that morphological evolution and biochemical evolution in structural genes can proceed at independent rates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cherty, L M -- Case, S M -- Wilson, A C -- New York, N.Y. -- Science. 1978 Apr 14;200(4338):209-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/635583" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anthropometry ; Anura/*anatomy & histology ; *Biological Evolution ; Biometry ; Genes ; Humans ; Pan troglodytes/*anatomy & histology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1982-07-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cann, R L -- Wilson, A C -- New York, N.Y. -- Science. 1982 Jul 23;217(4557):303-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17791499" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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