Publication Date:
1978-10-13
Description:
beta-Endorphin is not detectable in plasma from normal human subjects when measured under baseline conditions or after the subjects have received vasopressin, an agent that elevates beta-lipotropin and adrenocorticotropic hormone (ACTH). Significant amounts of beta-endorphin are present in plasma of patients with endocrine disorders associated with increased ACTH and beta-lipotropin production. Highly purified, natural beta-lipotropin is not peripherally converted to beta-endorphin in vivo in normal subjects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Suda, T -- Liotta, A S -- Krieger, D T -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):221-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/211585" target="_blank"〉PubMed〈/a〉
Keywords:
Addison Disease/blood
;
Adrenocorticotropic Hormone/*blood
;
Cushing Syndrome/blood
;
Endorphins/*blood
;
Humans
;
Nelson Syndrome/blood
;
Pituitary Gland/metabolism
;
beta-Lipotropin/*blood
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
