Publication Date:
2008-10-17
Description:
Understanding the pathogenesis of neuropsychiatric disorders is a substantial challenge for neurobiologists. It has long been hoped that identifying alleles that confer increased risk of such disorders would provide clues for neurobiological investigation. But this quest has been stymied by a lack of validated biological markers for characterizing and distinguishing the different disorders and by the genetic complexity underpinning these diseases. Now, modern genomic technologies have begun to facilitate the discovery of relevant genes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hyman, Steven E -- England -- Nature. 2008 Oct 16;455(7215):890-3. doi: 10.1038/nature07454.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Office of the Provost, Harvard University, Department of Neurobiology, Harvard Medical School, Massachusetts Hall, Cambridge, Massachusetts 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18923510" target="_blank"〉PubMed〈/a〉
Keywords:
Humans
;
*Mental Disorders/diagnosis/epidemiology/genetics/physiopathology
;
*Nervous System Diseases/diagnosis/epidemiology/genetics/physiopathology
;
Phenotype
Print ISSN:
0028-0836
Electronic ISSN:
1476-4687
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics