Publication Date:
2016-08-04
Description:
Article The N-terminal domain of APOBEC3G (A3G) is required for anti-HIV activity, HIV-1 viral infectivity factor (Vif) binds to this domain of A3G to mediate its degradation. Here, the authors use their crystal structures of this A3G domain alone and bound to single-stranded DNA to investigate the molecular details of this interaction. Nature Communications doi: 10.1038/ncomms12193 Authors: Xiao Xiao, Shu-Xing Li, Hanjing Yang, Xiaojiang S. Chen
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics