Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Expert systems
1 (1984), S. 0
ISSN:
1468-0394
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Computer Science
Notes:
Abstract: The purpose of this paper is to design an expert system or an intelligent procedure' that purports to screen hazard potentials of environmental chemicals on the basis of structure-activity relationships in the study of chemical carcinogenesis, particularly with respect to analysing the current state of known structural information about chemical carcinogens and predicting the possible carcinogenicity of untested chemicals An analysis of a computerised database of known carcinogens (knowledge base) is being performed using the structure-activity trees in order to test the validity of the tree as a classification scheme (inference engine) and to evaluate trends or patterns that may exist between chemical structure and specificity for target tissue, route of administration, and animal species. Practical applications of the structure-activity tree depend on its eventual validation as a predictor of carcinogenic activity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1468-0394.1984.tb00441.x
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