ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
of artificial blood catheters. This paper describes the immobilization of chitosan andheparin molecules on polyethylene terephthalate (PET) films by ozonization. The concentration ofperoxide groups (-OOH) was 1.72 × 10-7 mol/cm2 on the PET surface oxidized by ozonization.The results of X-ray photoelectron spectroscopy (XPS) indicate that chains of chitosan and heparinwere successfully immobilized on the PET films. The static contact angle(STA) of waterdecreases from 83.5° to 68.3° by immobilization of chitosan and heparin, which means that thehydrophilic properties of the modified PET is improved. The antithrombogenic property of PETsurface was evaluated by a platelet-rich plasma (PRP) adhesion test. The results indicate that thenumber of platelet adhered on the modified-PET surface incubated with PRP for 240 min decreasedsignificantly and platelets did not aggregate and distort
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.809.pdf