ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Cyano bonded phases
;
Residual silanol groups
;
Diethyldithiocarbamates
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary When a cyano bonded phase is used together with a nonaqueous eluent, it is universal that the silanol groups which remain at the surface of the silica gel after bonding affect the retention of solutes. With solutes containing such atoms as N, S and O, hydrogen bond may form between the solute and the residual silanol group, leading to dual retention mechanism. Based on the understanding of retention mechanism, methods were developed to separate metal-diethyldithiocarbamate (DDTC) chelates and crown ethers on cyano bonded phase, the mobile phase being a nonaqueous solvent containing triethylamine (TEA).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02324785
