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Enzyme localization as a mechanism of apparent active transport (1953)

Bierman, Arthur

Springer

Bulletin of mathematical biology 15 (1953), S. 509-522

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ISSN: 1522-9602

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Mathematics

Notes: Abstract A model based on enzyme localization is developed which gives rise to an apparent active transport of a metabolite into or out of cells. The model is applied to three simple situations, using Fick's equation and the Rashevsky approximation. It is shown that the apparent efficiency can be made as large as desired if, for constant reaction, the outer cell region is made sufficiently small, or, for autocatalytic reaction, if the metabolite concentration in the outer region is sufficiently small. The physical limitations imposed by this mechanism are developed for all three situations.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02476439

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