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Continuous cultivation of Streptomyces tendae in different media (1989)

Lohr, Dorothee ; Buschulte, Thomas ; Gilles, Ernst-Dieter

Springer

Applied microbiology and biotechnology 32 (1989), S. 274-279

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ISSN: 1432-0614

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: Summary The strain Streptomyces tendae is well suited for continuous cultivation because of its ability to grow and produce secondary metabolites simultaneously. Continuous culture experiments on defined medium show that growth is limited by nitrogen during steady state for the given medium composition. It is supposed that this also holds for complex medium. Production of antibiotics (several nikkomycins) occurs simultaneously with exponential growth. After switching from batch to continuous operation the fraction of biomass, consisting of pellets, decreases permanently.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00184973

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