ISSN:
0887-624X
Keywords:
nanoencapsulation
;
tyrosine
;
dyes
;
poly(isodecyl acrylate)
;
nanoparticles
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The polymerization of isodecyl acrylate (ISODAC) in vesicles of sodium di-2-ethylhexyl phosphate (SEHP) loaded with dyes or tyrosine was achieved. The study of the polymerization rate-conversion curve of the monomer confirmed that this polymerization was different from other polymerizations known, as it was proposed previously. Then the entrapment of hydrophilic molecules such as tyrosine or brilliant cresyl blue and lipophilic molecules such as sudan III into the nanoparticles was evaluated and confirmed by different methods. While tyrosine was not retained, brilliant cresyl blue and sudan III were entrapped inside nanoparticles. The size and the polarity of the molecules to be encapsulated, which are related to their diffusion coefficients and partition coefficients between water and the nanoparticle, seem to be the parameters responsible of the entrapment. © 1998 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 36: 3035-3043, 1998
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
