ISSN:
0021-9304
Keywords:
hydroxyapatite
;
hydroxyl groups
;
hexamethylene diisocyanate
;
isocyanatoethyl methacrylate
;
coupling agents
;
surface modification
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
The surface grafting reactions of a series of isocyanates with hydroxyapatite particles at different temperatures were studied by Infrared spectrophotometry (IR) and thermal gravimetric analysis (TGA). The study results show that both hexamethylene diisocyanate (HMDI) and isocyanatoethyl methacrylate (ICEM) react readily with HA while ethyl isocyanate acetate (EIA) and butyl isocyanate (BIC) have lower reactivity towards HA particles. It also has been found that the reaction of ICEM with HA follows a second-order reaction mechanism, despite the heterogeneous nature of the reaction, while the reaction of HMDI with HA does not due to the complexity of the reaction. Based on this study, it is concluded that ICEM and HMDI are suitable agents for the coupling of polymers due to their reactivity towards HA. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 40, 358-364, 1998.
Additional Material:
11 Ill.
Type of Medium:
Electronic Resource
