ISSN:
1750-3841
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Weanling male Fischer rats were fed semi-purified diets containing 0, 5, 10, 20, or 30% freeze-dried ground cabbage for 11 wk. “Control” groups received no aflatoxin B1 (AB1), “Ad lib AB1” groups received 1 ppm AB1 in the diets, and “Meal-fed AB1” groups received two weekly “meals” of AB1 in 3–5g of purified diet. The amounts of AB1 consumed per week was the same for both AB1 treated groups. Blood levels of α-fetoprotein (AFP), an onco-developmental gene product, were in the order: “Meal-fed AB1” 〉 “Ad-lio AB1” 〉 “Control.” Inhibition of AFP elevation by cabbage diets in both AB1-treated groups suggested that this vegetable may produce a hepatocarcinogenic protective effect. This effect has been observed in rats fed cauliflower (Boyd et al., 1979). Inhibition of AFP induction was correlated with increasing levels of dietary cabbage up to 20%. Cabbage diets also resulted in decreased intestinal transit time and increased relative liver weights.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2621.1981.tb04520.x
