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  • 1
    ISSN: 1352-8661
    Keywords: phase-contrast velocity encoding ; heart wall motion ; myocardial contraction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics
    Notes: Abstract We present a noninvasive MR technique to assess the regional myocardial wall motion quantitatively. The method uses a phase-contrast sequence in conjunction with a masking program allowing for exact myocardial wall demarcation. Five healthy volunteers, aged 24 to 36 years, were studied to evaluate normal heart motion. These data served as a normal reference to myocardial motion patterns determined in five patients, aged 51 to 73 years, with known coronary artery disease induced wall motion abnormalities. Tangential motion in normal subjects showed a clockwise rotation at the cardiac base and counterclockwise rotation at the apex. The maximal radial velocity was 30.45±5.9 mm/s−1. Dyskinetic myocardial motion could be differentiated from normal ventricular motion: The number of hypomotile segments as well as hypokinetic and paradox phases determined with this method correlated well with patients' ejection fractions (r 2=0.95). This preliminary study demonstrates the ability of velocity-encoded MR to characterize myocardial motion and differentiate normal from dyskinetic heart motility.
    Type of Medium: Electronic Resource
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