ISSN:
1420-9071
Keywords:
Guinea pig brain
;
cardiac output
;
morphine
;
cerebral blood flow
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Both acute and chronic administration of morphine resulted in an increase in the percent cardiac output received by brain. However, various brain regions were affected differently by the drug treatments. The greatest increases in percent cardiac output received after chronic administration of morphine occurred in pons and cerebellum, while the greatest increases after acute administration occurred in cortex and midbrain. The changes found are in contrast with earlier studies which suggest that morphine has no effect on cerebral blood flow.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02005885