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1.
PAPER CURRENT
Publication Date: 2014-07-30
Description: ACS Sustainable Chemistry & EngineeringDOI: 10.1021/sc500323a
Electronic ISSN: 2168-0485
Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
2.
PAPER CURRENT
Publication Date: 2014-07-30
Description: Accounts of Chemical ResearchDOI: 10.1021/ar500210d
Print ISSN: 0001-4842
Electronic ISSN: 1520-4898
Topics: Chemistry and Pharmacology
3.
PAPER CURRENT
Valorization of Biorefinery Side-Stream Products: Combination of Humins with Polyfurfuryl Alcohol for Composite Elaboration (2014)
Publication Date: 2014-07-30
Description: ACS Sustainable Chemistry & EngineeringDOI: 10.1021/sc5003769
Electronic ISSN: 2168-0485
Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
4.
PAPER CURRENT
Effect of Excipients on the Particle Size of Precipitated Pioglitazone in the Gastrointestinal Tract: Impact on Bioequivalence (2014)
Publication Date: 2014-07-30
Description: Abstract This study sought to understand the reasons for the bioinequivalence of a newly developed generic product of pioglitazone hydrochloride and to improve its formulation so that it is equivalent to that of the reference listed drug (RLD). In this clinical study, despite a similar in vitro dissolution profile, the new oral product exhibited a lower plasma concentration of pioglitazone compared to the RLD. The strong pH-dependency of pioglitazone solubility as a weak base indicates that pioglitazone would precipitate in the small intestine after being dissolved in the stomach. Thus, in vitro experiments were performed to investigate the effect of excipients on the particle size distribution of precipitated pioglitazone. Then, the impact of particle size on in vivo absorption was discussed. The precipitated pioglitazone from the RLD showed a peak for small particles (less than 1 μm), which was not observed in the precipitate from the new product. As an excipient, hydroxypropyl cellulose (HPC) influenced the particle size of precipitated pioglitazone, and the amount of HPC in the formulation was increased to the same level as that in the RLD. The precipitate from this improved product showed approximately the same particle size distribution as that of the RLD and successfully demonstrated bioequivalence in the clinical study. In conclusion, for drugs with low solubility, this type of analysis of the particle size distribution of precipitated drugs, in addition to the dissolution test, may help to obtain a better in vitro-in vivo correlation for oral absorption and to develop a bioequivalent product.
Electronic ISSN: 1550-7416
Topics: Chemistry and Pharmacology
5.
PAPER CURRENT
Study of the Curing Kinetics of Epoxy Resins with Biobased Hardener and Epoxidized Soybean Oil (2014)
Publication Date: 2014-07-30
Description: ACS Sustainable Chemistry & EngineeringDOI: 10.1021/sc500176z
Electronic ISSN: 2168-0485
Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
6.
PAPER CURRENT
Lignin Depolymerization with Phenol via Redistribution Mechanism in Ionic Liquids (2014)
Publication Date: 2014-07-30
Description: ACS Sustainable Chemistry & EngineeringDOI: 10.1021/sc5003424
Electronic ISSN: 2168-0485
Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
7.
PAPER CURRENT
Effect of ASTER DEM on the prediction of mean gravity anomalies: a case study over the Auvergne test region (2014)
Publication Date: 2014-07-30
Description: Abstract A precise gravimetric geoid determination requires height information and terrestrial gravity data with high accuracy and resolution. The height data is utilized for predicting mean free-air gravity anomalies as well as computing the topographic, atmospheric and downward continuation effects which are fundamental components of any geoid model. Nowadays the Digital Elevation Model (DEM) obtained from the Shuttle Radar Topography Mission (SRTM) has been widely used when an accurate regional DEM does not exist. In addition the DEM generated from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) was newly released by researchers from Japan and United States. In this study the effect of ASTER DEM on the estimating mean free-air gravity anomalies in geoid determination were investigated in the Auvergne test area where one of its regions exhibits one of the most rugged topography over the world. The numerical results show that ASTER DEM gives worse statistics than SRTM DEM with respect to the accuracy of the height. Using ASTER DEM introduces discrepancies (compared to SRTM DEM) in the range of \(-\) 4 to 10 mGal in the interpolation of free-air gravity anomalies. It is also proven that the geoid differences due to the use of ASTER DEM are a few centimeters, which remain below the accuracy level of the external GPS-levelling data.
Print ISSN: 1217-8977
Electronic ISSN: 1587-1037
Topics: Architecture, Civil Engineering, Surveying , Geosciences , Physics
Published by Springer
8.
PAPER CURRENT
On seismic monitoring of \(\hbox {CO}_{2}\) leak (2014)
Publication Date: 2014-07-30
Description: Abstract Geological storage of \(\hbox {CO}_{2}\) in mature sedimentary basins and deep saline water aquifer requires special considerations on the potential leakage pathways. Early detection of \(\hbox {CO}_{2}\) leakage from geological storage is one of the primary objectives of any carbon capture and storage technique. Thermodynamic properties of injected \(\hbox {CO}_{2}\) and formation fluid, and change in in-situ conditions may act as driving agent to \(\hbox {CO}_{2}\) leakage. Therefore, it is important to monitor the saturation of \(\hbox {CO}_{2}\) and identify the phase of \(\hbox {CO}_{2}\) during the injection, storage and after storage stages in order to monitor its possible migration and leakage risks. Seismic monitoring of sequestrated \(\hbox {CO}_{2}\) in subsurface is in practice in which Gassmann fluid substitution model is used to estimate porous rock and pore fluid properties. The seismic properties of \(\hbox {CO}_{2}\) contaminated fluids are predicted by Wood’s volume average formula. The analysis reveals that Wood’s approach is unable to account properly the properties of fluid mixture especially near bubble point pressure of \(\hbox {CO}_{2}\) /water mixture, thus unable to monitor primary leakage of \(\hbox {CO}_{2}\) . A modified approach based on thermodynamics is adopted for the detection of primary leakage of \(\hbox {CO}_{2}\) . The analysis shows that for a minute amount of free \(\hbox {CO}_{2}\) , the P-wave velocity is much lower than the values predicted by the Gassmann-Wood approach. The resulting normal reflectivity and AVO anomalies are much stronger than attained by conventional Gassmann-Wood approaches.
Print ISSN: 1217-8977
Electronic ISSN: 1587-1037
Topics: Architecture, Civil Engineering, Surveying , Geosciences , Physics
Published by Springer
9.
PAPER CURRENT
Development and Optimization of an Analytical System for Volatile Organic Compound Analysis Coming from the Heating of Interstellar/Cometary Ice Analogues (2014)
Publication Date: 2014-07-30
Description: Analytical ChemistryDOI: 10.1021/ac501974c
Print ISSN: 0003-2700
Electronic ISSN: 1520-6882
Topics: Chemistry and Pharmacology
10.
PAPER CURRENT
Comparison of three pollination methods for Eucalyptus argophloia, a small-flowered eucalypt (2014)
Publication Date: 2014-07-30
Description: Abstract Context Most studies assess pollination success at capsule maturity, and studies of pre-zygotic processes are often lacking. Aims This study investigates the suitability of controlled pollination for a potential forestry plantation species, Eucalyptus argophloia, by examining pre- and post-zygotic pollination success. Methods Pollen tube development, capsule set and seed set are compared following three-stop pollination, artificially induced protogyny (AIP), AIP unpollinated and open pollination. The fecundity of stored pollen was compared with that of fresh pollen. Results Three-stop pollination, AIP and open pollination had similar numbers of pollen tubes, but AIP unpollinated had none. Open pollination produced significantly more capsules and total number of seeds than the other treatments. There were significantly more seeds per retained capsule for the open pollination and three-stop pollination treatments than for the AIP and AIP unpollinated pollination treatments. There were no significant differences relative to the age of pollen. Conclusions Pre-zygotic success in terms of pollen tubes was similar for open-pollinated, three stop and AIP, but was not reflected in post-zygotic success when the open pollination and three-stop method produced significantly more seeds per retained capsule than the AIP treatments and open pollination yielded more seeds. Capsule set and total seed set for open pollination, and fewer capsules in controlled pollinations, may reflect physical damage to buds because of the small E. argophloia flowers. Suitable alternative breeding strategies other than controlled pollinations are discussed for this species.
Print ISSN: 1286-4560
Electronic ISSN: 1297-966X
Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
Published by Springer