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  • Books  (3,882)
  • thema EDItEUR::N History and Archaeology::NH History  (2,669)
  • bic Book Industry Communication::M Medicine  (1,213)
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  • Books  (3,882)
Years
  • 1
    Publication Date: 2024-04-01
    Description: On the occasion of the 100th anniversary of the University of Hamburg's main building, a ceremony was held on May 13th, 2011. The keynote speaker was Heinz-Elmar Tenorth, Professor of Historical Education in Berlin. Heinz Rieter and Rainer Nicolaysen awarded two lecture hall names, the socio-economic economist Eduard Heimann (1889-1967)(Lecture Hall H) and the lawyer Albrecht Mendelssohn Bartholdy (1874-1936) (Lecture Hall K). Thus, the programme for naming the seven lecture halls of the University's main building after outstanding scientists who were expelled from the Nazi regime came to an end.Detailed information on all names of the lecture hall can be found in the anthology 〈a href="http://hup.sub.uni-hamburg.de/purl/HamburgUP_Nicolaysen_Hauptgebaeude"〉The main building of the University of Hamburg as a place of remembrance〈/a〉, which was published on the occasion of the anniversary.
    Keywords: University of Hamburg ; Main Building ; 100 Years ; Celebratory Event ; Speeches ; Lecture Hall denomination ; Eduard Heimann ; Albrecht Mendelssohn Bartholdy ; National Socialism ; 20th Century ; Hamburg ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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  • 2
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    Taylor & Francis | Routledge
    Publication Date: 2024-04-01
    Description: This collection of thirteen essays examines sociolinguistic phenomena in a wide variety of marginal environments, providing both an overview of globalizaiton on the margins and a foundation for an expanded understanding of the processes of linguistic and cultural changes at work in these settings. Taking an expansive conceptual view of margins, the volume is organized in three parts, looking at examples of marginal spaces in the nation-state, in online environments, and in the peripheries of urban locations, globally to call attention to new and changing discursive genres, patterns, practices, and identities emerging in these spaces as a result of contemporary mobilities, the evolving global economy, and socio-political changes. With previous research previously confined to the study of globalization in urban areas, this volume opens the door for further research on the complex sociolinguistic processes resulting from globalization on the margins, making this an ideal resource for students and scholars in sociolinguistics, globalization and heritage studies, new media, anthropology, and cultural studies. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution (CC-BY)
    Keywords: Hoe Gaan Dit ; Linguistic Landscape ; Gregory Richardson ; Local Linguistic Landscape ; Xuan Wang ; Transcarpathian Oblast ; Massimiliano Spotti ; Dutch Caribbean Island ; Thayse Figueira Guimarães ; Smart Phones ; Branca Falabella Fabrício ; Sami Language ; Luiz Paulo Moita-Lopes ; Center Periphery Dynamics ; Paja Foudree ; Young Men ; Fie Velghe ; Language Ideologies ; Hirut Woldemariam ; Finnish Lapland ; Elizabeth Lanza ; Bongo Flava ; Binyam Sisay Mendisu ; Calypso Music ; Eleni Mariou ; Main Characters ; Zane Goebel ; Standard Ukrainian ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFD Psycholinguistics and cognitive linguistics::CFDM Bilingualism and multilingualism ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFB Sociolinguistics ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
    Language: English
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  • 3
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    University Press of Colorado | Utah State University Press
    Publication Date: 2024-04-02
    Description: The central issue Bush finds in these works is how their authors have dealt with the authority of Mormon Church leaders. As she puts it in her preface, "I use the phrase 'faithful transgression' to describe moments in the texts when each writer, explicitly or implicitly, commits herself in writing to trust her own ideas and authority over official religious authority while also conceiving of and depicting herself to be a 'faithful' member of the Church." Bush recognizes her book as her own act of faithful transgression. Writing it involved wrestling, she states, "with my own deeply ingrained religious beliefs and my equally compelling education in feminist theories that mean to liberate and empower women." Faithful Transgressions examines a remarkable group of authors and their highly readable and entertaining books. In producing the first significant book-length study of Mormon women's autobiographical writing, Bush rides a wave of memoir publishing and academic interest in autobiography and other life narratives. As she elucidates these works in relation to the religious tradition that played a major role in shaping them, she not only positions them in relation to feminist theory and current work on women's life writings but ties them to the long literary tradition of spiritual autobiography.
    Keywords: History ; Religion ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRM Christianity::QRMB Christian Churches, denominations, groups
    Language: English
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  • 4
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    Département des études, de la prospective et des statistiques
    Publication Date: 2024-04-01
    Description: Ce numéro de « Culture Prospective » est une anthologie de plusieurs textes d’Augustin Girard, fondateur du DEPS et observateur avisé de l’économie et la sociologie de la culture en France. Ces onze textes, qui parcourent la seconde moitié du XXème siècle de 1965 à 1997, permettent de découvrir le parcours et les idées d’Augustin Girard mais également de suivre l’évolution de l’activité prospective dans le secteur culturel.
    Keywords: H1-99 ; public policies ; cultural foresight ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-21
    Description: This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer.
    Keywords: R5-920 ; RM1-950 ; tissue engineering ; cyclodextrin ; permeability ; poly (vinylpyrrolidone-co-vinyl acetate) ; crystalline ; antibacterial ; drug delivery ; homogenization ; capsaicin ; combination therapy ; high-shear mixing ; cyclodextrin-inclusion complexes ; amorphous ; high-speed electrospinning ; PMVE/MA ; aqueous solubility enhancement ; sieve analysis ; Raman mapping ; Eudragit ; nanofibers ; psoriasis ; PCL ; essential oils ; parameters ; antibiotics ; xanthan gum ; carvedilol ; amorphous composite ; coaxial electrospinning ; insoluble drug ; NIR-triggered drug release ; fast dissolution ; electrospinning ; oral drug delivery ; electrospun nanofibers ; poly-cyclodextrin ; TRPV1 ; gallic acid ; solid dispersion ; photothermal therapy ; drug release ; applications ; bic Book Industry Communication::M Medicine
    Language: English
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  • 6
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    Studien Verlag
    Publication Date: 2024-04-01
    Description: The publication entitled "Vergangenheit, die nicht vergeht. Das Gedächtnis der Shoah in Frankreich seit 1945 im Medium Film" (A past, that doesn't pass. Holocaust Memory in France since 1945 in the Media Film) explores the basic transformations of the Holocaust-memory in France on the basis of French fiction films that are to be identified as part of cinematography of the Holocaust. The chosen approach that can be described as a history of memory referring to models of collective memory in cultural science studies. The aim is to specify the change of collective memory at the level of the particular filmic narratives and - by doing so - to identify and to analyze the long term development and ruptures in the French culture of remembrance since 1945. The empiric part of this study is preceded by methodological reflections that on the one hand permit a clear and differentiating application of the terms used in the current cultural studies of collective memory. On the other hand this chapter should help to conceive the material of research "Fiction Film" as primal source for historical science. The investigation is divided into five chronological parts and involves altogether a sample of 50 films into the general study before electing cases for deeper analyses.
    Description: Das Publikationsvorhaben mit dem Titel "Vergangenheit, die nicht vergeht. Das Gedächtnis der Shoah in Frankreich seit 1945 im Medium Film" erforscht anhand französischer Spielfilme - die als Teil einer Kinematografie der Shoah ausgemacht werden können - die grundlegenden Transformationen des Gedächtnisses der Shoah am Beispiel Frankreich. Mit einem gedächtnisgeschichtlichen Ansatz, der sich an den kulturwissenschaftlichen Modellen des kollektiven Gedächtnisses orientiert, konkretisiert die Arbeit den Wandel des Gedächtnisses anhand der jeweiligen filmischen Narrative und verfolgt auf diese Weise Langzeitentwicklungen und Brüche in der französischen Erinnerungskultur zwischen 1945 und heute. Dem empirischen Arbeitsteil sind theoretische und methodische Überlegungen vorgeschaltet, die einerseits einen eindeutigen und differenzierten Zugriff auf das Begriffsrepertoire der aktuellen kulturwissenschaftlichen Gedächtnisforschung erlauben und zugleich das Untersuchungsmaterial "Spielfilm" als Primärquelle der Geschichtswissenschaft fassbar bzw. bearbeitbar machen. Die Untersuchung gliedert sich in fünf chronologisch gereihte Abschnitte und bezieht insgesamt ein Corpus von 50 Filmen in die allgemeine Fragenstellung ein, bevor nach dem Prinzip des Fallbeispiels einzelne Filme einer genaueren Analyse unterzogen werden.
    Keywords: Shoah ; Collective Memory ; France ; Cinema ; Cultural representation ; Film ; Frankreich ; Gedächtnis ; Holocaust ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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  • 7
    Publication Date: 2023-12-21
    Description: Fluid intake has barely been assessed, and hydration status has only rarely been measured in epidemiological studies. This hampers attempts to assess the adequacy of water intake at a population level. However, although guidelines have been established to determine how much water humans require to avoid dehydration and to optimize physical and psychological function, limited data are available on the total water and beverages intake. Therefore, the percentage of population with inadequate water intake is unknown. There is a clear need for studies in different settings around the world that quantify total water and beverage intake and explore associations between types of beverages consumed and energy intake.
    Keywords: R5-920 ; Adequate hydration ; Beverages consumption ; Water and energy intake ; bic Book Industry Communication::M Medicine
    Language: English
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  • 8
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    Taylor & Francis | Classical Heritage and European Identities | Routledge
    Publication Date: 2024-04-01
    Description: This book examines how different agents and institutions within the Danish nation state have situated themselves within this complex landscape of competing appropriations of classical antiquity from the eighteenth century to the present day. In particular, it focuses on the use of classical heritages to construct both European and national identities (in the plural) and especially on how Danes in this period have engaged with a sense of European commonality through their engagements with the classical past.
    Keywords: Classical heritage ; European identities ; Europe ; Danish nation ; Denmark ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 9
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    Presses universitaires de Paris Nanterre
    Publication Date: 2024-04-01
    Description: Si c’est « malgré tout » qu’il faut défendre la sociologie, c’est malgré ce qu’elle est devenue. Bien loin de ses grandes espérances initiales et des splendeurs que nous ont léguées les Durkheim, Weber, Simmel, Mead, Elias, Mauss, etc. Ce que l’on appelle sociologie s’est peu à peu recroquevillé jusqu’à apparaître comme la « science (ou la pseudo science) des restes », la science de ce dont ne parlent ni les philosophes, ni les économistes, ni les historiens, ni les anthropologues, ni les théoriciens de la littérature, etc. Éclatée en de multiples chapelles théoriques ou idéologiques, privée de colonne vertébrale paradigmatique et institutionnelle, elle ne croit plus pouvoir trouver son unité que dans une référence de plus en plus incantatoire au « terrain » et à l’empirisme, et dans ses querelles infinies sur ce qui fait la bonne méthode ou le bon terrain. La sociologie classique, celle qu’il nous faut faire revivre et actualiser, se présentait tout autrement. Elle revendiquait hautement une approche empirique de la réalité et le souci d’établir des faits, elle aussi, mais elle n’imaginait pas que ce puisse être accompli hors-théorie et sans enjeux normatifs, c’est-à- dire éthiques et politiques... Dit autrement, elle se vivait comme le lieu et le moment généraliste de la science sociale générale. C’est cette sociologie là, autrement dit la science sociale générale, qui nous fait désormais défaut et qu’on appelle ici à renaître de ses cendres.
    Keywords: H1-99 ; philosophie politique ; économie ; capitalisme ; utilitarisme ; approche empirique ; scientificité ; sociologie ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 10
    Publication Date: 2024-04-01
    Description: After a long process, the reopening of Milanese canals has become one of the fundamental actions of the Town Plan approved in 2019. A strategic project that plans to reactivate the covered section of the Naviglio Martesana and the Cerchia Interna, reuniting Adda and Ticino rivers, and give new life to the great Renaissance project that Leonardo himself had worked on. In its methodological approach and in the specific outcome achieved, we can recognize elements of continuity with Leonardo’s thinking and contribute to a territorialist reflection on its current relevance.
    Keywords: Milan water city ; reopening Navigli ; Leonardo da Vinci ; thema EDItEUR::N History and Archaeology::NH History
    Language: Italian
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  • 11
    Publication Date: 2024-04-01
    Description: This book is a reflection on the politics of heritage in Europe at the present time, in a moment of pluralised conceptions of the political, social and demographic organisation proper to Europe. It is not a book that seeks to survey, define or characterise an enduring ‘European heritage’ as an entity, but rather to explore what heritage does – how it is understood, instrumentalised and what it enables – within what we will argue is a ‘critical’ moment for both identities and geopolitics in Europe.
    Keywords: European heritage ; political organisation ; social organisation ; demographic organisation ; Europe ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general
    Language: English
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  • 12
    Publication Date: 2024-04-01
    Description: Dans le sport, l'innovation s'impose de façon non équivoque, au moins en comparaison avec d'autres domaines de la vie sociale. La maîtrise de l'innovation - qu'elle soit ou non technique - et l'obligation de maintenir la recherche de solutions nouvelles sont bien des facteurs d'accès indispensables à la réussite sportive. Des chercheurs en sociologie, histoire économique, management et gestion des entreprises, sciences du sport et communication, ont confronté leurs travaux sur l'évolution de sports aussi divers que l'aviron à ses débuts, le rugby amateur ou professionnel, le football, la voile de compétition, le surf et les sports de glisse en Aquitaine, avec un grand crochet par la Martinique pour les compétitions de yoles martiniquaises… Ils examinent les conditions d'émergence et les multiples configurations que peut prendre l'innovation. Ils dégagent la morphologie des processus d'innovation également étudiés sous l'angle des politiques publiques territoriales et au sein d'associations sportives ou de clubs omnisports marqués depuis peu par des phénomènes de professionnalisation.
    Keywords: H1-99 ; association sportive ; politique publique ; club omnisport ; professionnalisation ; nouvelle technologie ; innovation sportive ; sport ; réussite ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 13
    Publication Date: 2024-04-04
    Description: The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences.
    Keywords: Discipline of representation, History, Semiotics, Science, Technology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society
    Language: Italian , English
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  • 14
    Publication Date: 2023-12-21
    Description: It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against pathogens, communicate in a well-organized fashion with the brain to maintain homeostasis and regulate a set of neural functions. Perturbation in this brain-immune interactions due to inflammatory responses may lead to psychiatric and neurological disorders. Microglia are one of the essential cells involved in the brain-immune interactions. Microglial cells are now not simply regarded as resident tissue macrophages in the brain. These cells are derived from myeloid progenitor cells in the yolk sac in early gestation, travel to the brain parenchyma and interact actively with neurons during the critical period of neurogenesis. Microglia provide a trophic support to developing neurons and take part in the neural wiring through the activity-dependent synapse elimination via direct neuron-microglia interactions. Altered microglial functions including changes in the gene expression due to early life inflammatory events or psychological and environmental stressors can be causally related to neurodevelopmental diseases and mental health disorders. This type of alterations in the neural functions can occur in the absence of infiltration of inflammatory cells in the brain parenchyma or leptomeninges. In this sense, the pathogenetic state underlying a significant part of psychiatric and neurological diseases may be similar to “para-inflammation”, an intermediate state between homeostatic and classical inflammatory states as defined by Ruslan Medzhitov (Nature 454:428-35, 2008). Therefore, it is important to study how systemic inflammation affects brain health and how local peripheral inflammation induces changes in the brain microenvironment. Chronic pain is also induced by disturbance in otherwise well-organized multisystem interplay comprising of reciprocal neural, endocrine and immune interactions. Especially, early-life insults including exposure to immune challenges can alter the neuroanatomical components of nociception, which induces altered pain response later in life. Recently the discrete roles of microglia and blood monocyte-derived macrophages are being defined. The distinction may be further highlighted by disorders in which the brain parenchymal tissue is damaged. Therefore, studies investigating the dynamics of immune cells in traumatic brain injury and neurotropic viral infections including human immunodeficiency virus, etc. as well as neurodegenerative diseases such as amyotrophic lateral sclerosis are promising to clarify the interplay between the central nervous and immune systems. The understanding of the histological architecture providing the infrastructure of such neuro-immune interplay is also essential. This Frontiers research topic brings together fourteen articles and aims to create a platform for researchers in the field of psychoneuroimmunology to share the recent theories, hypotheses and future perspectives regarding open questions on the mechanisms of cell-cell interactions with chemical mediators among the nervous, immune and endocrine systems. We hope that this platform would reveal the relevance of the studies on multisystem interactions to enhance the understanding of the mechanisms underlying a wide variety of neurological and psychiatric disorders.
    Keywords: R5-920 ; RC346-429 ; RC581-607 ; brain-immune interaction ; fatigue ; pain ; HIV ; neuroinflammation ; traumatic brain injury ; depression ; microglia ; amyotrophic lateral sclerosis ; autism ; bic Book Industry Communication::M Medicine
    Language: English
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  • 15
    Publication Date: 2024-04-01
    Description: Arua como lugar estratégico para a observação da vida urbana no que esta tem de mais peculiar é o tema central deste livro. A proposta é simples e exploratoria: procurar diferentes aproximações a esta realidade complexa a partir do olhar da antropologia, da história, da sociología e da arquitectura, em contextos geográficos e temporais distintos. A rua surge como problema a identificar e como lugar privilegiado para a troca e circulação de saberes disciplinares. Enquanto imagem e símbolo de um modo de vida urbano, lugar onde ocorrem as sociabilidades mais “típicas” da cidade, a rua condensa e viabiliza todo um imaginário feito de discursos, memórias e emoções, que atravessam e elaboram simbolicamente a cidade naquilo que ela tem de mais original. Espaço, tempo e sociabilidade são apenas tres tópicos que ajudam a ler as contribuições da presente colectânea, cujos autores partilham urna preocupação fundamental: apreender a rua à escala de quem a vive, de perto e em situação... Na Paris popular oitocentista, nos actuais campos de refugiados ou na Lisboa dos séculos xix e xx, vamos ao encontro dos lugares da rua.
    Keywords: H1-99 ; city ; urban space ; urban anthropology ; urban history ; socialization ; urban life ; thema EDItEUR::N History and Archaeology::NH History
    Language: Portuguese
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  • 16
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    Universidad Santiago de Cali | Diálogo entre las humanidades
    Publication Date: 2024-04-01
    Description: Published
    Description: Los avances de las llamadas ciencias duras, las ingenierías y las ciencias básicas son un hecho, al punto que son los motores de mayor fuerza en los avances científicos en las últimas décadas. También es un hecho que el sentido de utilidad del conocimiento, el papel de la innovación de las ciencias ha cobrado fuerza y valor situando a las Humanidades en niveles cada vez más distantes aparentemente, de los centros de toda de decisiones en los problemas de nuestro tiempo (Acevedo y Prada Dussán, 2017). En la actualidad la atención del pensamiento está centrado en “en un ‘enfoque orientado al mercado’, que favorece las ciencias biológicas, médicas y tecnológicas, y ha ayudado a reforzar una jerarquía disciplinaria en la que (…) [las] artes y Humanidades han luchado por llamar la atención” Hazelkorn (2015, p. 1).
    Keywords: Humanidades ; Estética ; Historia ; Diálogos ; Educación y Ética ; Comunicación Social y Publicidad ; Filosofía ; thema EDItEUR::N History and Archaeology::NH History
    Language: Spanish
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  • 17
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    Firenze University Press
    Publication Date: 2024-04-01
    Description: The paper presents a reasoned review of digital resources useful for historians and the teaching of public history. This review will not be limited only to the tools of search and treatment of sources on the web, but will be directed above all to provide a guidance framework - which will be by the very nature of the digital constantly evolving over time - of those tools, methods and narratives that make use of digital to enhance teaching and research.
    Keywords: public history ; digital history ; review ; teaching ; research ; thema EDItEUR::N History and Archaeology::NH History
    Language: Italian
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  • 18
    Publication Date: 2023-12-21
    Description: Um livro valioso, que analisa com clareza o papel fundamental dos recursos humanos para a saúde e o desenvolvimento, bem como o contexto e o impacto da reforma sanitária e a relação entre as iniciativas internacionais, nacionais e locais em prol da mudança dos serviços de saúde. Além de examinar os antecedentes e os principais atores da área de recursos humanos e explicar com detalhes as negociações que visavam transformar em prioridade nacional a formação de recursos humanos e a distribuição dos trabalhadores de saúde no território, Recursos Críticos está apoiado em uma sólida pesquisa bibliográfica, testemunhos fascinantes e análise original, que fazem da obra uma contribuição significativa no campo da memória da saúde pública e uma ferramenta indicativa de perspectivas de futuro para trabalhadores na área da saúde. É uma pesquisa histórica de grande qualidade, voltada para a análise da cooperação Opas-Brasil, e um incentivo à realização de novos estudos sobre as interfaces entre a atuação de agências internacionais e os interesses nacionais, partindo do conceito de arenas ou espaços de negociação.
    Keywords: R5-920 ; Brasil ; Recursos humanos em saúde ; Planos e programas de saúde ; Cooperação técnica ; Organização Pan-Americana da Saúde ; bic Book Industry Communication::M Medicine
    Language: Portuguese
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  • 19
    Publication Date: 2023-12-21
    Description: Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have specific defects in DNA repair pathways, and that these defects may predispose for sensitivity and resistance to various classes of cytotoxic agents. Breast, ovarian and other cancers develop in the setting of inherited DNA repair deficiency, and these cancers may be more sensitive to cytotoxic agents that induce DNA strand breaks, as well as to inhibitors of PARP activity. A series of recent clinical trials has tested whether PARP inhibitors can achieve synthetic lethality in hereditary DNA repair-deficient tumors. At the current time, mutation of BRCA serves as a potential, but not comprehensive, biomarker to predict response to PARP inhibitor therapy. Mechanisms of resistance to PARP inhibitors are only recently being uncovered. Future studies seek to identify sporadic cancers that harbor genomic instability rendering susceptibility to PARP inhibitors that compound lethal DNA damage.
    Keywords: R5-920 ; RC254-282 ; DNA reapir ; PARP inhibitor ; Homologous Recombination ; combination therapy ; DNA Damage ; Cancer ; bic Book Industry Communication::M Medicine
    Language: English
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: This reprint addresses the relationship between education and sustainability from various perspectives. The main issues discussed in the 12 collected papers are concerned with (1) the quality of education, (2) SDG policy and implementation, (3) education and societal development, (4) students’ learning, and (5) global experience.
    Keywords: bridging academics ; regional sustainability ; knowledge diffusion ; public–private partnership ; multi-node knowledge link model ; stakeholders ; paradox of Chinese learners ; learning concept ; virtue model ; mind model ; Confucian culture ; mindset intervention ; interaction ; iterative process ; persuasive ; stealthy ; education for sustainable development ; China ; education policy ; sustainable development ; ESD ; SDGs ; sustainability ; higher education ; indicators ; rankings ; assessment ; university rankings ; green universities ; green campus ; education ; learning ; educational innovation ecosystem ; education sustainability ; university-industry collaboration ; Chinese higher education ; digital age ; talents cultivation ; information literacy ; online learning process ; innovation performance ; nature education ; urban residents ; perception ; survey ; sustainable growth ; social-emotional skills ; self-management skills ; solution-focused ; Kids’Skills method ; education partnership assistance ; common prosperity ; balanced and sustainable development ; capacity building ; professional learning communities in interdisciplinary subjects ; teachers’ professional development ; teacher learning ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: English
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  • 21
    Publication Date: 2023-12-21
    Description: This e-book provides the insight into occupational health and safety problems, challenges and solutions of the dairy sector. Thirty-two authors have been sharing their results and knowledge reflecting the challenges from small scale farming up to industrial style. The worldwide trend of growing farm sizes and a reduction in numbers is one of the major drivers for the changes in the working environment. Musculoskeletal disorders are among the most prevalent health problems of people working on farms. Nevertheless mechanisation has not reduced the number of complaints, and new problems arise due to the changing working environment.
    Keywords: R5-920 ; RA1-1270 ; immigrant workers ; Dairy farming ; OHS ; MSS ; MSD ; bic Book Industry Communication::M Medicine
    Language: English
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  • 22
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    Éditions de la Maison des sciences de l’homme
    Publication Date: 2024-04-01
    Description: Depuis quelques années, le Brésil occupe une place de plus en plus importante sur la scène internationale en conséquence de grands changements socio-économiques – et plus particulièrement d’une réduction significative de la pauvreté et de l’inégalité des revenus. Cet ouvrage vise à présenter au public francophone, y compris au lecteur profane en matière de politique sociale brésilienne, la mise en place et l’évolution des différents programmes d’allocations sociales, dont le plus connu est la Bourse-Famille. L’analyse porte sur les caractéristiques de base de ces programmes, leurs formats, les changements conceptuels intervenus au cours du temps, le ciblage des bénéficiaires, les effets des allocations sur la composition du revenu des ménages ainsi que sur le déclin de la pauvreté et de l’inégalité. Enfin, l’accent est mis sur les défis à relever pour perfectionner cette politique des allocations afin de mieux protéger les enfants pauvres, la population la plus vulnérable actuellement.
    Keywords: H1-99 ; pauvreté ; allocations sociales ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-21
    Description: Gluten is the major protein of wheat and other cereals (rye and barley); it is responsible for triggering celiac disease (CD) in genetically predisposed individuals. Until a few years ago, CD was the major (if not the only) well-known gluten-related disorder. However, in recent years, it has become clear that gluten proteins may activate different pathological mechanisms, leading to a wide spectrum of human diseases, including non-celiac gluten sensitivity (NCGS), gluten ataxia, neuro-psychiatric disorders, and many others. Conceptually, we have therefore moved from a Ptolemaic to a Copernican system, i.e., CD is no longer the “center of the universe”, but is just one of the possible worlds of gluten intolerance. Many other gluten planets do indeed exist and deserve the attention of researchers and clinicians alike. Although different gluten-related disorders show specific epidemiological, pathophysiological, and clinical aspects, these conditions share a trigger and treatment: the gluten-free diet. For a very long time, awareness of these disorders has been limited and, therefore, the epidemiology of gluten-related disorders is still a “work in progress”. Current research strives to clarify the boundaries between these entities, their disease mechanisms, and how a proper diagnosis can be implemented.
    Keywords: R5-920 ; gluten-related disorders;celiac disease;gluten intolerance ; bic Book Industry Communication::M Medicine
    Language: English
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    University of California Press
    Publication Date: 2024-04-01
    Description: Placing Empire examines the spatial politics of Japanese imperialism through a study of Japanese travel and tourism to Korea, Manchuria, and Taiwan between the late nineteenth century and the early 1950s. In a departure from standard histories of Japan, this book shows how debates over the place of colonized lands reshaped the social and spatial imaginary of the modern Japanese nation. In turn, this sociospatial imaginary affected the ways in which colonial difference was conceptualized and enacted. The book thus illuminates how ideas of place became central to the production of new forms of colonial hierarchy as empires around the globe transitioned from an era of territorial acquisition to one of territorial maintenance.
    Keywords: geography of civilization ; colonial difference ; taiwan ; japanese empire ; korea ; spatial history ; place ; tourism ; manchuria ; geography of cultural pluralism ; Indigenous peoples ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    Éditions Contrechamps
    Publication Date: 2024-03-26
    Description: Dans cet ouvrage collectif placé sous la direction de Jean-Louis Leleu et Pascal Decroupet, la musique de Pierre Boulez est approchée de façon à la fois analytique et esthétique : l'approche rigoureuse du langage musical conduit à des réflexions sur ses enjeux. Les différents auteurs nous font entrer dans l'atelier du compositeur, éclairant ses procédés d'élaboration, les mutations d'une œuvre à l'autre, l'évolution de sa pensée, les projets inaboutis et certains éléments qui l'ont influencé. Sont étudiées en détail des pièces comme le Livre pour quatuor, Le Marteau sans maître, la Troisième Sonate pour piano, Figures, Doubles, Prismes, Éclat/Multiples ou Rituel, mais aussi des pièces retirées. Il s'agit de contributions originales qui apportent une somme d'informations nouvelles et décisives pour la compréhension d'une pensée musicale ayant marqué en profondeur les cinquante dernières années. Pour qu'ils soient plus lisibles et plus faciles à consulter, les exemples musicaux et les fac-similés des manuscrits de Boulez ont été gravés sur le CD-ROM joint.
    Keywords: musique ; XXème siècle ; philosophie ; esthétique ; composition ; analyse musicale ; thema EDItEUR::D Biography, Literature and Literary studies::DN Biography and non-fiction prose::DNB Biography: general::DNBL Biography: writers ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 26
    Publication Date: 2024-04-01
    Description: Mises en place en 1981, les zones d'éducation prioritaires (ZEP) font désormais partie du paysage éducatif français. Pourtant, on connaît encore mal les évolutions et les effets d'une politique fondée sur la prise en charge collective et décentralisée des problèmes éducatifs. L'analyse sociologique telle qu'elle est menée ici conduit à mettre 1 accent sur les conditions locales qui favorisent ou qui freinent 1 investissement scolaire des parents, des enseignants et de nouveaux acteurs du champ éducatif : élus, animateurs, bénévoles... A travers une approche ethnographique comparative - une zone rurale et une zone urbaine sont étudiées parallèlement - qui se nourrit des apports des travaux anglo-saxons, l'auteur présente une réflexion nouvelle sur le rôle des dynamiques locales dans la reproduction et dans la transformation du système éducatif.
    Keywords: H1-99 ; ZEP ; système scolaire ; zone rurale ; éducation ; système éducatif ; zone urbaine ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 27
    Publication Date: 2023-12-21
    Description: Microglia are essential for the development and function of the adult brain. Their ontogeny, together with the absence of turnover from the periphery and the singular environment of the central nervous system (CNS), make microglia a unique cell population compared to other tissue-macrophages. The unique properties and functions of microglial cells, such as their role in synaptic pruning or the exceptional capacity to scan the brain parenchyma and rapidly react to its perturbations, have emerged in recent years. In the coming years, understanding how microglia acquire and maintain their unique profiles in order to fulfil distinct tasks in the healthy CNS and how these are altered in disease, will be essential to develop strategies to diagnose or treat CNS disorders with an immunological component. This Research Topic covers several aspects of microglial biology, ranging from their origin and the functional role of microglia during development and lifespan, their molecular properties compared with other brain and peripheral immune cells to microglial phenotypes and functional states in neurodegenerative diseases and brain tumours. In conclusion, the present Research Topic provides a comprehensive overview of our current understanding of several cellular and molecular mechanisms that make microglia a unique immune cell population within the healthy CNS as well as under inflammatory, neurodegenerative and tumorigenic processes.
    Keywords: R5-920 ; RC346-429 ; RC581-607 ; inflammation ; brain tumour ; neurodegeneration ; microglia ; ontogeny ; bic Book Industry Communication::M Medicine
    Language: English
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    Maison des Sciences de l’Homme d’Aquitaine | Maison des Sciences de l'homme d'Aquitaine
    Publication Date: 2024-04-01
    Description: La recherche et l'aménagement du territoire des années 1960 nous ont légué l'image persistante de réseaux urbains régionaux et nationaux, construits sur la base de rapports hiérarchiques entre des villes de stature et de rayonnement inégaux. Comment ces positions, assignées par la puissance objective des agglomérations, mais aussi par la représentation et par la volonté aménagistes ont-elles évolué depuis près de trente ans ? Pour répondre à cette question, nous avons choisi de partir du cas spécifique de Pau, promue sous-capitale régionale par le schéma d'armature urbaine de l'Aquitaine (1965), mais soucieuse aussi, dès cette époque, d'affirmer son leadership sur l'aire quelque peu mythique des Pays de l'Adour, concurremment à Tarbes et surtout à Bayonne. Pour tenter d'éclairer, aujourd'hui, l'actualité des hiérarchies, des concurrences et des complémentarités entre cités, s'exprimant dans le cadre de l'Aquitaine (et au-delà lorsque les frontières administratives ne correspondent plus à l'articulation des réseaux), nous avons privilégié une approche des rapports urbains qui passe par l'étude de l'économie, de la géographie, mais aussi de la sociologie des services marchands aux entreprises. La poussée de ces activités de pointe illustre en effet l'expansion rapide d'un secteur tertiaire supérieur très expressif de l'Influence réelle qu'exercent les villes sur l'espace géographique ; très démonstratif de leur capacité, en somme, à forger des régions.
    Keywords: H1-99 ; service marchand ; secteur tertiaire ; économie ; aménagement du territoire ; frontière administrative ; agglomération ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Presses universitaires de Provence
    Publication Date: 2024-04-01
    Description: L’ex-voto est un don fait par un fidèle à un personnage céleste en remerciement d’une protection. En Provence, pendant plus de trois siècles, ces ex-voto ont souvent pris la forme d’un petit tableau déposé dans un sanctuaire, montrant le protecteur et les circonstances de la protection. Ces tableaux votifs présentent des images de la vie d’autrefois, dans des circonstances particulières, celles du danger, qui ont motivé la demande d’intervention céleste. À côté de ces scènes du vécu quotidien, ils offrent aussi une représentation du sacré, et de son lien avec les hommes. Le présent ouvrage se fonde sur une analyse exhaustive des quatre mille ex-voto provençaux, mais en présente une version destinée à un large public. En effet il est construit à partir de la reproduction photographique de plus de deux cents ex-voto, dont la majorité inédits. Ce sont ces photos qui servent de support à l’analyse et au commentaire, faisant pénétrer le lecteur dans l’univers matériel quotidien (maladies, naissances, accidents du travail, accidents de la circulation terrestre et maritime, guerre et violence, dangers de la foudre ou des eaux…) et dans les représentations des recours célestes de nos ancêtres (les saints intercesseurs, Marie…), face au danger.
    Keywords: Provence ; sacré ; ex-voto ; réprésentation ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Presses de l’Université de Montréal
    Publication Date: 2024-04-01
    Description: Suivre l’itinéraire universitaire et politique de Guy Rocher, c’est littéralement refaire l’histoire du Québec de la dernière moitié du siècle dernier. Qu’on ne s’étonne donc pas que cet ouvrage aborde tout autant l’œuvre du sociologue que, plus largement, les boule­ver­sements d’une société confrontée aux défis incessants de sa modernisation. Si les témoignages nous font pénétrer dans l’intimité de l’homme et du citoyen, les analyses signées par des professeurs de renom nous dévoilent, sous un jour neuf, le paysage social, politique et scientifique du Québec. Écrits à partir de perspectives disciplinaires les plus diverses (science politique, droit, sociologie, histoire, etc.), les textes qui composent cet ouvrage nous permettent de mieux comprendre, non seulement l’évolution globale de la société québécoise, mais les enjeux bien contemporains que l’histoire a légués en héritage à la génération présente. Guy Rocher est né à Berthierville en 1924. Ses études classiques terminées, il joint les rangs de la Jeunesse étudiante catholique. Il fait par la suite ses études en sciences sociales à l’Université Laval avec le père Georges-Henri Lévesque et son doctorat en sociologie à l’Université Harvard sous la direction de Talcott Parsons. À son retour, il enseigne la sociologie d’abord à l’Université Laval puis, en 1960, il accepte le poste de directeur du Département de sociologie à l’Université de Montréal, dont il est toujours membre du corps professoral. Depuis 1983, il est aussi chercheur au Centre de recherche en droit public de cette même université. Il a été membre de la commission Parent (1961-1966), sous-ministre au Développement culturel (1977-1979) et au ministère du Développement social (1981-1983) du Gouvernement du Québec. Il est récipiendaire de plusieurs prix académiques, dont le prix Marcel-Vincent, le prix Léon-Gérin, le prix Molson, et le prix William Davidson de la Société royale du Canada, dont il est membre depuis 1974. Son ouvrage Introduction à la sociologie générale (1968) a été traduit en plusieurs langues et est encore aujourd’hui un livre de référence majeur pour l’enseignement de la sociologie.
    Keywords: H1-99 ; conditions sociales ; sociologie ; Québec ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 31
    Publication Date: 2023-12-21
    Description: The non-classical HLA class I molecule HLA-G is different from classical HLA class I molecules because of the low polymorphism in the coding region, the fact that HLA-G primary transcript is alternatively spliced in seven isoforms, and the inhibitory action on immune cells. Although HLA-G is low polymorphic, variants in both promoter and 3’ un-translated region (UTR) of HLA-G locus regulate its expression. In healthy conditions, a basal level of HLA-G gene transcription is observed in most cells and tissues; however, translation into HLA-G protein is restricted to trophoblasts in the placenta, where it participates in promoting tolerance at the fetal-maternal interface. HLA-G is also expressed by thymic epitelial, cornea, mesenchymal stem cells, nail matrix, pancreatic beta cells, erythroid, and endothelial precursors. HLA-G can be neo-expressed in adult tissues in pathological conditions, and its expression has been documented autoimmune disorders, viral infections, and cancer. In the latter setting de novo HLA-G expression is associated with the capability of tumor cells to evade the immune control. In the last decade it has become evident that HLA-G expression on T cells and antigenpresenting cells confers to these cells tolerogenic properties. This Research Topic focused on i) summarizing updated clinical and immunological evidences that HLA-G expression is associate with beneficial or detrimental tolerance, ii) gathering new insights into the mechanisms governing the expression of HLA-G in healthy and pathological conditions, such as pre-eclampsia, and iii) examining the mechanisms underlying HLA-G mediated tolerance.
    Keywords: R5-920 ; RC581-607 ; Pregnancy ; Autoimmunity ; Immuno-modulation ; Pre-Eclampsia ; Infections ; Exosomes ; HLA-G ; polymorphisms ; tolerance ; Cancer ; bic Book Industry Communication::M Medicine
    Language: English
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  • 32
    Publication Date: 2024-04-01
    Description: Le contrôle du paludisme requiert plusieurs moyens de lutte associés au sein de stratégies adaptées au contexte environnemental et épidémiologique. Les moustiquaires imprégnées de pyréthrinoïdes constituent l’un des outils préventifs dans cette lutte : leur utilisation est simple et permet une protection individuelle et collective durable et accessible à tous. Cependant, depuis plus de dix ans, Anopheles gambiae, le principal vecteur du paludisme en Afrique, est devenu résistant à de nombreux insecticides. Cette résistance pose des questions d’ordre fondamental et opérationnel : le comportement des moustiques s’en trouve-t-il modifié ? Cette résistance s'accompagne-t-elle d'une réduction significative de l'efficacité des moustiquaires imprégnées ? À travers la synthèse de travaux de recherche réalisés tant en laboratoire que sur le terrain, cet ouvrage révèle pourquoi les moustiquaires imprégnées d'insecticides resteront, pendant longtemps encore, une arme indispensable dans la lutte contre le paludisme.
    Keywords: H1-99 ; culicidae ; lutte contre les moustiques ; paludisme ; prévention ; vecteur de maladie ; anopheles gambiae ; insecticide ; moustique ; résistance aux insecticides ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-01
    Description: Kazimierz Moczarski (1907–1975) was a journalist, soldier, and political prisoner. His life exemplifies a Central European biography under Nazism and Comunism. The addictive and moving Civility in Uncivil Times reveals the story of a man who defended law and democracy all his life. Moczarski fought for it in the authoritarian Poland of the 1930s. During the Second World War, he partook in the resistance movement. After the war, he spent eleven years in a Stalinist prison, including nine months in one cell with the Nazi Jürgen Stroop, who commanded the brutal pacification of the Warsaw Ghetto. The communists imprisoned Moczarski’s wife. After release, he rebuilt the broken marriage, rejoined social life, and wrote a work about meeting Stroop. Translated into many languages, Conversations with the Executioner is a thorough study of totalitarianism.
    Keywords: anti-Semitism ; Battle ; Biography ; Civility ; Kazimierz ; Machcewicz ; Moczarski ; Moczarski's ; Polish ; political prisoner ; post-Stalinist thaw ; Prison ; prison letters ; Quiet ; Stalinism ; Stalinist ; terror ; Times ; Truth ; Uncivil ; Underground ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 34
    Publication Date: 2024-04-01
    Description: Constituem a obra capítulos derivados de diferentes perspectivas acerca do tema da televisão digital terrestre, compondo um panorama prismático de diversos aspectos integrantes da inovação a partir das plataformas já existentes e da problemática da implantação, abarcando tópicos distintos componentes da implantação e manutenção do novo sistema - autores na sociedade tecnológica, diversidade cultural e política de informação, educação e participação por meio da interatividade, produção de conteúdos audiovisuais, regulação e políticas de educação, mobilidade e democracia, modelos de negócio, a viabilidade da interatividade, cenários e desafios para as emissoras públicas, a implantação no Brasil e na Espanha, a convergência com instituições educacionais, gestão de conteúdos narrativos, democracia digital, a implantação no Pará e a atuação de emissoras em cada estado, a transição do sinal analógico para o digital, a repercussão midiática sobre a implantação e as controvérsias e desinformações sobre o "apagão digital".
    Keywords: H1-99 ; SOCIAL SCIENCE ; thema EDItEUR::N History and Archaeology::NH History
    Language: Portuguese
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Advancements in digital technologies are reshaping the world of dentistry, from prosthodontics to implant dentistry. Intraoral scanners, facial scanners, 3D printers, and milling machines have revolutionized the clinical approach and operative workflow in daily practice. However, digital dentistry brings several challenges to clinicians due to the rapid evolution of new technologies and the lack of evidence-based guidelines for their correct use. The aim of this Special Issue is to cover the latest advances in the development and application of digital technologies in prosthetic and implant dentistry. We wish to provide both clinicians and researchers with a comprehensive and up-to-date source of information on current trends, limitations, and potential future applications of digital technologies in daily clinical practice.
    Keywords: dental implants ; digital impression ; intraoral scanner ; CAD/CAM materials ; toothbrushing wear ; surface ; roughness ; surface integrity ; alveolar remodeling ; tooth extraction ; intraoral digital scanning ; imaging superimposition ; less traumatic surgery ; socket healing ; implantology ; computer-aided surgery ; image-guided surgery ; zygomatic implants ; navigation system ; dental implant ; bone level ; prospective study ; sub-crestal placement ; emergence profile ; guided surgery ; digital workflow ; stereolithographic surgical guide ; accuracy ; CAD–CAM ; DICOM–STL ; static guided surgery ; clinical study ; intraoral scanners ; digital dentistry ; impression techniques ; full-arch impression ; elderly population ; dimensional measurement accuracy ; implant scan ; operator ; precision ; scan area ; trueness ; occlusion ; overloading ; complications ; implant-supported restorations ; marginal bone loss ; oral implantology ; intraoral scan ; cone-beam computed tomography ; oral surgery ; emergence angle ; retrospective study ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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  • 37
    Publication Date: 2024-04-01
    Description: L'image est un média, peut-être le premier, le plus ancien. Depuis Lascaux, les individus, les groupes, les pouvoirs politiques et religieux en ont fait un allié ou un péril. Tout au long du xxe siècle, les images se sont immiscées partout. Acheminées par le cinéma, la télévision ou la presse écrite, véhiculées par Internet, elles s'installent au cœur du public comme du privé. Avec l'émergence des médias de masse, l'image et la politique ont renforcé leurs liens, forgeant une relation où les deux champs s'interpellent et se nourrissent intensément. L'étude du champ politique doit donc se saisir de ce corpus toujours plus foisonnant. Elle doit s'y atteler sans se fixer de limites a priori sur une définition des images politiques et sans se contenter d'étudier leur contenu (politique). Réunissant une trentaine de contributions dans une perspective internationale et interdisciplinaire, cet ouvrage croise les supports, les espaces socioculturels et les temporalités afin de mettre au jour les invariants et les ruptures, qu'il s'agisse du choix des thèmes ou des modes de mise en scène de la politique à chaque époque ou selon chaque régime. Couvrant les xxe et xxie siècles, l'ouvrage permet de relier différentes « époques médiatiques » et de voir les continuités, les filiations, les apports, les recompositions et les complémentarités entre des médias dits traditionnels (cinéma, télévision, photographie, presse écrite) et les nouveaux médias à l'âge du numérique (Internet, téléphones portables, jeux vidéo) dans leur façon de s'emparer ou d'être saisis par la politique.
    Keywords: H1-99 ; société ; médiatisation ; média ; communication ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 38
    Publication Date: 2024-04-01
    Description: This book is a collection of essays by prominent historians from Austria, Germany, Ukraine, Poland and Russia, who undertook a thorough and detailed study of one as yet inadequately researched aspect of the First World War--the occupation of Ukraine by the Central Powers in 1918. The book provides a new and fresh perspective on the historical context of Ukraine’s struggle for independence following the First World War.
    Description: Die Ukraine war zu Ende des Ersten Weltkrieges zwischen den Zwängen des zerfallenden Russischen Reiches, den Mittelmächten, die große Gebiete besetzten, und einer starken, aber zersplitterten Unabhängigkeitsbewegung, eingezwängt. Erstmals versucht mit dieser Studie ein internationales Historikerteam mit Materialien aus Archiven in Moskau, St. Petersburg, Kiew, Warschau, Wien, London, Paris, Bern, Prag, Washington und aus den deutschen Archiven ein faszinierendes Bild des Unabhängigkeitszwanges der Ukraine zu zeichnen. Dabei wurde auch ein bisher kaum bearbeitetes Thema aufgebrochen: Die vielfach rücksichtslose Besatzung des Landes durch deutsche und österreichischungarische Truppen 1918 und ihre Auswirkungen und Folgen.
    Keywords: First World War ; Ukraine ; Russian Civil War ; Interwar Years ; Erster Weltkrieg ; Ukraine ; Russischer Bürgerkrieg ; Zwischenkriegszeit ; Austria-Hungary ; Bolsheviks ; Kiev ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-01
    Description: The book is a comparative case study of collective memory in two small communities situated on two Central-European borderlands. Despite different pre-war histories, Ukrainian Zhovkva (before 1939 Polish Żółkiew) and Polish Krzyż (before 1945 German Kreuz) were to share a common fate of many European localities, destroyed and rebuilt in a completely new shape. As a result of war, and post-war ethnic cleansing and displacement, they lost almost all of their pre-war inhabitants and were repopulated by new people. Based on more than 150 oral history interviews, the book describes the process of reconstruction of social microcosm, involving the reader in a journey through the lives of real people entangled in the dramatic historical events of the 20th century.
    Keywords: Collective Identity ; Deportation and resettlement ; Displaced ; Forgetting ; Galicji ; Holocaust and ethnic cleansing ; Kopernika ; Memories ; Mikołaja ; Naukowe ; Odzyskanych ; pamięć ; pamięci ; Poland ; Polish-Ukrainian conflict ; Politics of memory ; polskich ; Post ; Przesiedlenia ; przykładzie ; Remembering ; Second World War ; społecznej ; Studium ; Ukraine ; ukraińskiej ; Uniwersytetu ; Wydawnictwo ; Wylegala ; Ziem ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    Taylor & Francis | Routledge
    Publication Date: 2024-04-02
    Description: Back in 1989, many anticipated that the end of the Cold War would usher in the ‘end of history’ characterized by the victory of democracy and capitalism. At the thirtieth anniversary of this momentous event, this book challenges this assumption. It studies the most recent era of contemporary European history in order to analyse the impact, consequences and legacy of the end of the Cold War for Western Europe. Bringing together leading scholars on the topic, the volume answers the question of how the end of the Cold War has affected Western Europe and reveals how it accelerated and reinforced processes that shaped the fragile (geo-)political and economic order of the continent today. In four thematic sections, the book analyses the changing position of Germany in Europe; studies the transformation of neoliberal capitalism; answers the question how Western Europe faced the geopolitical challenges after the Berlin Wall came down; and investigates the crisis of representative democracy. As such, the book provides a comprehensive and novel historical perspective on Europe since the late 1980s.
    Keywords: Central and Eastern Europe ; Cold War ; End of Communism ; End of History ; Fall of the Berlin Wall ; Free Markets ; Nationalism ; Populism ; Shock Therapy ; 1989 ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHQ History of other geographical groupings and regions ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history
    Language: English
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    Bloomsbury Academic | Bloomsbury Academic
    Publication Date: 2024-04-02
    Description: Why does the history of dogmatism deserve our attention? This open access book analyses uses of the term, following dogmatism from Victorian Britain to Cold War America, examining why it came to be regarded as a vice, and how understandings of its meaning have evolved. Whilst the field of scientific thought is committed to continuous innovation, ideas about dogmatism – with their roots in ancient philosophy – are pervasive in scientific thought today. Carrying connotations of both vice and ecclesiastical authority, the term’s prevalence during the ‘age of science’, and the rise of new thought categories such as totalitarianism and creationism, prompted scholars to repeat the old wisdom that science is incompatible with dogmatism. Tracing the concept across decades and different disciplines, Paul and Stoeger demonstrate how it has survived not only the passage of time, but changes in language and scientific methodologies. The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycollections.com. Open access was funded by Dutch Research Council (NWO).
    Keywords: dogmatism ; history of science ; history of dogmatism ; historiography ; history of the humanities ; scientific methodology ; history of dogma ; 19th century history ; 20th century history ; 21st century history ; age of science ; scientific thought ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHA History: theory and methods
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Maison des Sciences de l’Homme d’Aquitaine
    Publication Date: 2024-04-01
    Description: La 26e Université Sportive d'Été organisée conjointement par l'Union Nationale des Clubs Universitaires et l'Union des Journalistes de Sport en France s'est déroulée du 4 au 6 septembre 2008 sur le thème suivant : Sport et Santé, sortir des contradictions, apporter des solutions. Organisée à Strasbourg, avec le soutien efficace du Strasbourg Université Club, elle a largement profité du rayonnement international de la Cité, en étant accueillie au Centre Européen de la Jeunesse et en ouvrant ses séquences d'analyse, de présentation d'expériences novatrices et de débats à des compétences européennes de premier plan. « Le sport, c'est la santé » : ce type d'adage à la vie opère comme un écran de fumée par rapport à la réflexion et à la valorisation d'une action cohérente, d'autant que les termes de sport et de santé recouvrent chacun des notions différentes et pas toujours complémentaires. Comment renouer avec l'éducation sportive - chez l'athlète assidu comme chez des pratiquants ayant une simple activité d'entretien physique - sinon en remettant à l'ordre du jour l'examen des interactions dynamiques entre sport et santé ? « Sport et santé » composent une question majeure posée à et par une société plus que jamais marquée par la sédentarité, le vieillissement de la population et des inégalités socio-économiques persistantes. A l'occasion de cette USE, chercheurs universitaires, enseignants d'EPS, éducateurs et dirigeants sportifs, élus politiques et acteurs administratifs, journalistes, porteurs de projets ont pu se montrer à la hauteur des enjeux en ébauchant des orientations pertinentes.
    Keywords: H1-99 ; éducation sportive ; inégalité socio-économique ; sédentarité ; entretien physique ; santé ; sport ; athlète ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 44
    Publication Date: 2024-04-01
    Description: This essay considers a number of travellers’ writings about Africa which are reread to construct and deconstruct Italian colonial identity. It focuses on Cesare Cesari’s Viaggi africani di Pellegrino Matteucci (1932), which deems Matteucci a precursor of Fascist colonialism and contributor to Fascist “colonial science”. The essay then moves on to explore the more recent rereading by Angelo Del Boca and Igiaba Scego of respectively Indro Montanelli’s XX Battaglione Eritreo (1936) and Errico Emanuelli’s Settimana nera (1961). By bringing together and rereading these texts, the essay maps the transformations of Italianness from colonial to postcolonial times and reveals how colonial identity relied on a series of gender, racial and sexual tropes of exploration and conquest.
    Keywords: Africa ; colonial identity ; race ; sex ; gender ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 45
    Publication Date: 2023-12-21
    Description: Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They enter the afferent lymphatic vessel that serves as a conduit to transport the motile lymphocytes to the draining lymph node. Lymphatic vessels (LVs) are present in most vascularized tissues. They are traditionally regarded as passive conduits for soluble antigens and leukocytes. Afferent LVs begin as blind ended capillaries, which give rise to collecting vessels that merge and connect with draining lymph nodes (dLNs). Initial lymphatic capillaries are composed of Lymphatic Endothelial Cells (LECs) connected by discontinuous cell junctions, which join to form larger collecting lymphatic vessels, and ultimately feed into the LN subcapsular sinus. Within the LN, LECs are localized to the subcapsular, cortical, and medullary sinuses, where they interact with incoming and exiting leukocytes. LECs, and in general LN stromal cells, have emerged in the recent years as active players in the immune response. In support to this,studies have shown that the immune response generated during inflammation and under pathologic conditions is accompanied by modeling of the LVs and generation of new lymphatics, a process known as lymphangiogenesis. These facts strongly suggest that LECs and stromal LN cells in general, are not inert players but rather are part of the immune response by organizing immune cells movement, exchanging information and supplying survival factors. The purpose of this research topic is to review the role of the LECs during immune homeostasis and cancer. Considering the critical role of lymphangiogenesis in many pathologies like chronic and acute inflammation, autoimmunity, wound healing, graft rejection, and tumor metastasis, it is important to understand the molecular mechanisms that govern the cross talks between the LECs and immune cells during homeostasis and inflammation.
    Keywords: R5-920 ; RC581-607 ; Liver Injury ; Lymphatic Vessels ; Lymphatic Vasculature ; Tumor Microenvironment ; PD-L1 ; Antigen Presenting Cells ; Lymphatic Endothelial Cells ; T cell trafficking ; T cells ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: In this Special Issue, we have published papers on the health-promoting effects of nutraceuticals from different sources, and their effects in different pathologies. Extracts from plants have been analyzed, for example, extracts from olive leaves, Mikania micrantha, the devil’s claw, raspberries and others, alongside marine phytoplankton, egg-yolk and marketed dietary supplements. The effects of these extracts and dietary supplements have been studied in diseases associated with obesity, and in diseases where inflammation pathways are involved. The effectiveness of resveratrol and curcumin to support the anticancer activity of cisplatin has also been reported, as well as the ability of devil’s claw root extract to stimulate the CB2 receptors in synoviocytes in osteoarthritis patients. The anti-oxidant effect of marine phytoplankton has been studied on muscle damage, both in humans and in an animal model, and the effects of the metabolite of antocianin were analyzed in a mouse model of amyotrophic lateral sclerosis. Finally, reviews on the use of lactoferrin, ω3 and ω6 and abscisic acid have been reported, in addition to the crosstalk between prostate cancer and microbiota inflammation. Although it is not yet possible to draw definitive conclusions on the use of nutraceuticals, several mechanisms of action for many of them have been further clarified.
    Keywords: fertility ; ingredients ; male reproduction ; semen parameters ; supplements ; allithiamine ; garlic ; hyperglycaemia ; advanced glycation end-products ; cytokines ; abscisic acid ; prediabetes ; type 2 diabetes mellitus ; metabolic syndrome ; insulin resistance ; adipocyte browning ; AMP-activated protein kinase ; food supplement ; frambinone ; meal frequency ; open-field test ; elevated plus maze ; sensory motor gating ; pre-pulse inhibition ; c-Fos ; amyotrophic lateral sclerosis ; anti-inflammatory ; antioxidant ; phenolic acid ; neuroprotective ; neurodegeneration ; obesity ; overweight ; beta-glucans ; chitosan ; follow up study ; weight loss programs ; weight gain ; weight loss ; body weight changes ; phytoplankton ; antioxidants ; muscle damage ; muscle recovery ; muscle soreness ; Viburnum opulus ; phenolic compounds ; adipogenesis ; PPARγ ; lipase inhibition ; green tea ; epigallocatechin ; lipid profile ; high-fat diet ; fast food ; osteoarthritis ; nutraceuticals ; polyphenols ; volatile compounds ; β-caryophyllene ; eugenol ; FAAH ; cannabinoid receptors ; phospholipases ; lactoferrin ; bovine milk ; nutraceutical ; human health ; resveratrol ; curcumin ; cisplatin ; head and neck cancer ; cell cycle ; apoptosis ; prostate cancer ; microbiota ; nutraceutical compounds ; fecundation ; inflammation ; cytokine ; growth factors ; metabolomics ; lipidomics ; ω-3PUFAs ; ω-6PUFAs ; endocannabinoids ; CRC ; fatty acids ; Gymnema inodorum ; gymnemic acid ; Mikania micrantha ; anti-hypercholesterolemia ; steatosis ; olive leaf ; macrophages ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-21
    Description: Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.
    Keywords: R5-920 ; RM1-950 ; chitosan ; intestinal epithelial cells ; ocular delivery ; amphiphilic polymers ; cornea ; tight junction modulator ; cyclodextrin ; permeability ; gemini surfactant ; transferrin ; compound 48/80 ; epithelial permeability ; cervicovaginal tumors ; nanoparticles ; confocal laser scanning microscopy ; safety ; formulation ; salcaprozate sodium ; intestinal absorption ; FITC-dextran ; curcumin ; block copolymers ; nasal vaccination ; whole leaf ; brush border ; ocular drug delivery ; vaccine adjuvant ; nanoparticle ; nasal delivery ; efflux ; permeation enhancers ; absorption enhancers ; nose to brain delivery ; small intestine ; epithelium ; CNS disorders ; absorption modifying excipients ; insulin ; absorption enhancer ; gel ; intestinal delivery ; thermogel system ; Caco-2 ; biocompatibility studies ; absorption enhancement ; man ; PN159 ; poorly absorbed drug ; tryptophan ; tight junction ; oral macromolecule delivery ; penetration enhancer ; intestinal permeation enhancers ; nanocrystals ; simvastatin ; nanomedicine ; enterocyte ; N-dodecyl-?-D-maltoside (DDM) ; cell-penetrating peptide ; quaternization ; KLAL ; nasal ; nasal permeability ; transmucosal drug delivery ; Caco-2 cells ; mast cell activator ; penetration enhancers ; drug delivery ; nose-to-brain ; bioenhancer ; polymeric micelles ; mucoadhesion ; cell-penetrating peptide (CPP) ; simulated intestinal fluid ; vaginal delivery ; nasal formulation ; pharmacokinetic interaction ; sodium caprate ; clinical trial ; transmucosal permeation ; drug absorption enhancer ; sugar-based surfactants ; nanocapsules ; imatinib ; teriparatide ; osteoporosis ; hydrophobization ; F-actin ; combined microsphere ; transepithelial electrical resistance ; oral delivery ; ocular conditions ; metabolism ; antimicrobial peptide ; permeation enhancer ; drug administration ; antiepileptic drug ; amino acid ; in vivo studies ; sodium cholate (NaC) ; epithelial transport ; preclinical ; nose to brain transport ; pharmacokinetics ; chitosan derivatives ; ophthalmology ; tight junctions ; sheep ; cationic functionalization ; GLP-1 ; pulmonary ; and liposome ; cytochrome P450 ; claudin ; P-glycoprotein ; in situ hydrogel ; mucoadhesiveness ; PTH 1-34 ; Aloe vera ; oral peptides ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Scale up and implementation of new point-of-care (POC) diagnostics is a global health priority to enable the adoption of new evidence-based POC diagnostics and to replicate and extend the reach of POC diagnostics. Global private and public sector agencies have significantly increased their investment in the development of POC diagnostics to meet the unmet needs of patients in resource-limited settings, particularly disease burdened settings with limited access to laboratory infrastructure. However, previous research has demonstrated that the availability of health technologies in these settings does not always guarantee patient-centered outcomes. The applicability, effectiveness and sustainability of diagnostic technologies is affected by the involvement of all stakeholders during planning and implementation, which must be relevant to each specific context and sensitive to local culture. Factors such as infrastructure, resources, values and characteristics of participants can influence the implementation, scalability and sustainability of health interventions such as POC diagnostics. This book, “Implementation and Scale up of Point of Care (POC) Diagnostics in Resource-Limited Settings”, presents literature reviews and primary research studies focusing on the implementation and scale up of POC diagnostics in resource-limited settings.
    Keywords: point-of-care-ultrasound ; ultrasound ; implementation ; point of care ultrasound ; augmented reality ; telemedicine ; spatial accessibility ; blood group ; rhesus type ; point-of-care testing ; maternal healthcare ; Upper East Region ; Ghana ; point-of-care ultrasound ; medical education ; syphilis ; maternal mortality ; interrupted time series ; segmented regression analysis ; point-of-care CD4+ t testing ; qualitative survey ; acceptability ; patients ; healthcare providers ; primary healthcare clinics ; HIV self-testing ; scale-up ; key stakeholder ; quality HIV point-of-care-diagnostics ; nominal group technique ; stakeholder engagement ; self-testing ; novel coronavirus disease-19 ; blockchain ; artificial intelligence ; geographical access ; glucose-6-phosphate dioxygenase deficiency ; antenatal care ; upper east region ; schistosomiasis ; barriers to diagnostics ; access to healthcare ; end-user perspectives ; neglected tropical diseases ; Nigeria ; case management ; electronic health information system ; diagnosis ; treatment ; point-of-care ; low and middle income countries ; point-of-care diagnostics ; healthcare services ; COVID-19 era ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
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  • 49
    Publication Date: 2024-04-01
    Description: Les migrations internationales sont devenues l'un des enjeux majeurs des rapports entre les États. Dans ce cadre, les mouvements de réfugiés et de déplacés liés aux conflits politiques, identitaires ou territoriaux témoignent de la fragilité de constructions nationales encore si souvent contestées. Les principales modalités d'accueil des réfugiés montrent bien les obstacles à l'intégration comme les limites d'une assistance humanitaire dont l'action reste plus curative que préventive. Mais la paix revenue, le retour et la réintégration des réfugiés dans leur pays d'origine se heurtent encore à des difficultés politiques, juridiques et économiques qui sont autant de freins à la reconstruction nationale et qui, par là même, dessinent les migrations internationales du futur. Tels sont quelques-uns des grands thèmes évoqués dans les différentes contributions de cet ouvrage, dont certaines, comme celles sur les camps palestiniens du Liban, sur la revendication territoriale des Sahraouis ou encore sur le difficile retour des réfugiés cambodgiens, sont d'une actualité toujours brûlante.
    Keywords: H1-99 ; politique migratoire ; refugié ; migration ; migration de retour ; transfert de population ; ONG ; discrimination ; action humanitaire ; droit international ; géopolitique ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Presses universitaires de Rennes
    Publication Date: 2024-04-02
    Description: Aux États-Unis, la notion de race est utilisée de manière routinière par les médecins en tant que variable biologique, culturelle ou sociale, selon les situations de soins. Croisant les notions de citoyenneté, de responsabilité et de droits civiques, ainsi que les questionnements autour de la politisation de la science, cet ouvrage retrace l’histoire de la médicalisation du corps noir par la profession psychiatrique aux États-Unis, du xxe siècle jusqu’à l’époque contemporaine. Conjuguant l’histoire et la sociologie, il est ainsi question de retracer les différents régimes par lesquels la notion de race a été jugée pertinente par les psychiatres pour naturaliser les différences corporelles des années 1920 jusqu’à l’époque contemporaine. En s’appuyant sur un corpus d’archives personnelles de médecins, d’institutions de soins et de centres de recherche en psychiatrie, ainsi que sur une enquête qualitative réalisée auprès de psychiatres en Californie, ce livre démontre que la catégorie de race irrigue encore et toujours les pratiques et les discours institutionnels, aussi bien dans les représentations que les médecins véhiculent des corps soignés, que dans les stratégies de naturalisation du social employées pour prendre en charge leurs patients.
    Keywords: psychology ; racialization ; United States of America ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSL Ethnic studies
    Language: French
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    Les Presses de l’Université d’Ottawa | University of Ottawa Press
    Publication Date: 2024-04-01
    Description: This volume commemorates the 40th anniversary of the University of Ottawa’s Department of Criminology, founded in 1968. It relates the history of the department from its origins to today, focusing on the theoretical debates that have influenced its critical and self reflexive approach to criminology. The contributions to this volume continue in that vein by questioning the traditional perspective of criminology on a variety of topics including police studies, mental health, political violence, suicide, and crime prevention. Rights and Voices reveals the significant role that the University of Ottawa has played in redefining criminology to advocate activism, social justice, and compassion.
    Keywords: H1-99 ; law ; criminology ; social justice ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 52
    Publication Date: 2024-04-01
    Description: Faire de la musique un objet géographique ne signifie pas seulement reconnaître en elle un nouvel outil d'analyse des espaces ou un moyen d'agir sur ces derniers. En nous appuyant sur les démarches antérieures menées dans le champ des sciences sociales, nous postulons l'irréductibilité de l'objet musical à une seule dimension disciplinaire. Nous lui attribuons une interdisciplinarité située, territorialisée, mise en tension par les logiques contradictoires entre ancrage local et mondialisation, temps courts et temps longs, perspectives normatives et/ou descriptives, dynamiques créatives... Cadrées par des approches culturelles différentes, les propositions rassemblées dans cet ouvrage rendent compte d'une dynamique collective à l'œuvre. Un réseau scientifique en construction met aujourd'hui en relation la géographie de la musique avec l'urbanisme, la sociologie, les sciences politiques, l'anthropologie, la philosophie ou encore les sciences de la communication. Ensemble, ces disciplines nous invitent à considérer la musique dans les espaces, lieux et territoires qu'elle produit et consomme. Invitation au dialogue, cet ouvrage tente également de relier les productions francophones et anglophones. Il espère ainsi participer à une vision collective et ouverte des recherches sur le phénomène musical.
    Keywords: H1-99 ; géographie ; urbanisme ; espace ; communication ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 53
    Publication Date: 2024-04-01
    Description: No ano de 2017, o Brasil se posicionou como o maior produtor mundial de cana-de-açúcar e de açúcar, e o segundo de etanol. O que explica essa constância da cana-de-açúcar e dos seus derivados nas pautas de produção e de exportação brasileiras? Quais são as condicionantes físicas que explicam a expansão dos canaviais e, consequentemente, das unidades manufatureiras e industriais do açúcar, etanol e agroenergia em certas regiões do território brasileiro? Como esses determinantes, associados a fatores históricos, políticos e econômicos, levaram a arranjos territoriais e a impactos socioambientais diferenciados ao longo desses cinco séculos? Essas indagações nortearam o desdobramento dos temas tratados neste livro, descortinando um longo processo iniciado no período colonial, que aglutinou enorme quantidade de variáveis de abrangência política, econômica, social e tecnológica, ancoradas nas características físicas, sobretudo hidroclimatológicas, dos solos e do relevo das áreas onde a cana-de-açúcar, os engenhos e as usinas foram implantados.
    Keywords: H1-99 ; thema EDItEUR::N History and Archaeology::NH History
    Language: Portuguese
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  • 54
    Publication Date: 2024-04-01
    Description: This volume is an investigation of how Augustine was received in the Carolingian period, and the elements of his thought which had an impact on Carolingian ideas of ‘state’, rulership and ethics. It focuses on Alcuin of York and Hincmar of Rheims, authors and political advisers to Charlemagne and to Charles the Bald, respectively. It examines how they used Augustinian political thought and ethics, as manifested in the De civitate Dei, to give more weight to their advice. A comparative approach sheds light on the differences between Charlemagne’s reign and that of his grandson. It scrutinizes Alcuin’s and Hincmar’s discussions of empire, rulership and the moral conduct of political agents during which both drew on the De civitate Dei, although each came away with a different understanding. By means of a philological–historical approach, the book offers a deeper reading and treats the Latin texts as political discourses defined by content and language.
    Keywords: Augustine ; De Civitate Dei ; Rulership ; Alcuin ; Hincmar ; Early medieval Europe ; Carolingian ; Ethics ; Political thought ; Charlemagne ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    Maison des Sciences de l’Homme d’Aquitaine | Maison des Sciences de l'homme d'Aquitaine
    Publication Date: 2024-04-01
    Description: En Aquitaine, première région vitivinicole française, la vigne est présente sur la majeure partie des territoires, et la filière, avec ses exploitations en Appellation d'Origine Contrôlée, ses caves coopératives et ses maisons de négoce, constitue une forte composante de l'économie régionale. Les grands crus sont les principaux référents pour l'image des vins aquitains et tirent vers le haut l'ensemble du vignoble, et cependant les vins de Bordeaux occultent la diversité et la richesse des vins aquitains, ce qui nuit à une image de l'Aquitaine comme pays du vin. Vignobles et vins en Aquitaine s'attache à étudier ce paradoxe. La première partie, dans une synthèse de nombreux écrits de recherche, explique comment les histoires agraire, économique et humaine de la région ont fait du vin une spécificité aquitaine, inscrite dans les paysages et les sociétés, et évalue le rôle de la « place de Bordeaux ». La seconde partie propose des éclairages plus circonstanciés, regroupés en deux thèmes : les facteurs et marqueurs de la construction des territoires viticoles constituent un premier axe d'étude, suivi par les représentations et la défense de l'image qui forment un second champ. Les territoires viticoles aquitains sont des constructions sociales complexes, génératrices d'une identité forte et porteuse. Cet ouvrage a été réalisé par la collaboration d'historiens, géographes, économistes ou œnologues au sein de la MSHA et dans le cadre de programmes pluridisciplinaires du CERVIN (composante de l'UMR ADES). Il soulève des problématiques telles que l'articulation entre société et terroir, les effets déformants du système AOC ou les logiques territoriales « de clocher » qui ont perturbé la création d'une identité régionale. Les recherches de ces différents auteurs nous permettent de comprendre comment les viticulteurs aquitains ont été en mesure de maintenir une production que le monde entier envie encore malgré la crise.
    Keywords: H1-99 ; économie régionale ; histoire agraire ; appellation d’origine contrôlée ; œnologie ; vigne ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Neural control of human motor output and how it is modified by alterations in physical activity levels is complex and multidimensional. The use of various experimental designs has vastly increased our knowledge of how the nervous system integrates descending, segmental, and ascending information to produce motor outputs, yet there is still much to learn. A more complete picture of the neurophysiology underlying the control of human motor outputs may prove useful in guiding rehabilitation programs aimed at reducing motor impairments following disease or injury. The purpose of this Special Issue is to collect original articles that explore neural excitability in various states. Studies examining neural excitability on a moment-to-moment basis (acute) or following prolonged periods of exercise or skill training and disuse (chronic) are encouraged. Original research studies using various experimental measures (e.g., transcranial magnetic stimulation, transmastoid electrical stimulation, single motor unit recordings, electroencephalography, and measures of spinal reflexes) in various states (e.g., fatigued, non-fatigued, and resting) during different types of motor outputs (tonic or dynamic) are encouraged. Experimental studies and literature reviews are welcome.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
    Language: English
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    Publication Date: 2024-04-01
    Description: L’urbanisation à l’échelle planétaire et la conscience croissante des problèmes écologiques font de l’« urbain » un objet privilégié pour l’action publique et la recherche. C’est en effet grâce à la perspective urbaine que nous parvenons aujourd’hui à une meilleure compréhension des sociétés contemporaines et des milieux de vie. En articulant les dimensions sociales, écologiques, politiques et matérielles, les recherches actuelles apportent de nouvelles connaissances sur les théories et définitions de l’urbain, les populations urbaines et la production de leur cadre de vie. Les enjeux sont de taille. Ils touchent à la qualité de vie des citadins et à la forme de nos sociétés : diversification des populations, accroissement des inégalités, recompositions des flux, des échelles et des pouvoirs urbains, changements de l’environnement planétaire, etc. Le présent ouvrage, qui repose sur un important travail collectif sur les villes des Nords et des Suds, propose un panorama engagé de ces enjeux présents et, surtout, à venir pour la recherche urbaine.
    Keywords: H1-99 ; ville ; politique ; densité ; action publique ; environnement ; égalité ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación | Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación ; Universidad Nacional de Misiones ; Universidad Nacional de General Sarmiento
    Publication Date: 2024-04-01
    Description: This book analyzes the role of the argentine liberal-conservative intellectuality before the last dictatorship, kown as "Proceso de Reorganización Nacional" (1976-1983).
    Description: Published
    Description: El presente trabajo analiza el rol de la intelectualidad liberal-conservadora argentina ante la última dictadura, el "Proceso de Reorganización Nacional" (1976-1983). El libro estudia las posiciones e intervenciones de un conjunto de catorce actores: Álvaro Alsogaray, Alberto Benegas Lynch, Germán Bidart Campos, Horacio García Belsunce, Jorge Luis García Venturini, Mariano Grondona, Juan Segundo Linares Quintana, Mario Justo López, José Alfredo Martínez de Hoz, Víctor Massuh, Jaime Perriaux, Ambrosio Romero Carranza, Carlos Sánchez Sañudo y Ricardo Zinn. La elección de estos nombres implica considerar un abanico amplio de trayectorias que componen figuras intelectuales de diversidad, unidas sin embargo por muchos más vínculos que la adscripción política. La obra se interna en la historia político-intelectual de un espacio ideológico aún poco explorado desde los estudios sobre la intelectualidad, las derechas y la propia dictadura, reponiendo los diversos espacios ocupados por estos hombres, sus proyectos, coincidencias, polémicas y desencantos en un momento clave de la historia argentina.
    Keywords: D1-2009 ; H1-99 ; dictadura militar ; Argentina ; political violence ; military dictatorship ; violencia política ; thema EDItEUR::N History and Archaeology::NH History
    Language: Spanish
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    Taylor & Francis | Routledge
    Publication Date: 2024-04-02
    Description: Ages, Christopher, Contemporary, Everyday, Fletcher, Middle, Objects, Political, World
    Keywords: Ages, Christopher, Contemporary, Everyday, Fletcher, Middle, Objects, Political, World ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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    ANU Press
    Publication Date: 2024-04-02
    Description: The story of the Communist Party of Australia has been told in various ways. Until now, however, archival collections that have borne on this story have been relatively inaccessible to the ordinary, interested reader. This book begins to redress that deficiency by bringing together 85 key documents from the Russian State Archives of Social and Political History (RGASPI), selected from a collection of thousands of documents concerning the relations between the Communist International and the Communist Party of Australia. The selection focuses on the relationship between the CPA and the Comintern because the activities of the CPA are essentially incomprehensible without understanding the international communist context within which the CPA operated. That context was dominated by the newly-created Soviet state and its decision to authorize and utilize a network of communist parties throughout the world. The documents in this work suggest three major propositions about the relationship between the CPA and the Comintern. First, that the Comintern was crucial in the formation of the CPA, via its emissaries, instructions and authority. Second, that the Comintern played a major role in directing the policies of the CPA in domestic matters (not to mention in international matters, where the Comintern’s decisions were supreme). And third, that the leadership of the CPA was, from 1929 onwards, shaped, trained and authorized by the Comintern. With access to the documents, readers now have a chance not just to hear the voices of the times, but to make their own judgements about the relationship between the CPA and Moscow. The book also includes two extended introductory essays that outline the development of the Comintern and its relations with the CPA, as well as supporting materials that provide information on individuals, organizations and tactics mentioned within the documents themselves.
    Keywords: politics and government ; relations ; australia ; history ; soviet union ; communism ; Capitalism ; Moscow ; Trade union ; Working class ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: English
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    Publication Date: 2024-04-01
    Description: Le trachome, la maladie des « cils qui poussent à l’intérieur », est la deuxième cause de cécité dans le monde. Bien qu’elle soit susceptible d’être prévenue et traitée, elle frappe encore près de 80 millions de personnes, en particulier dans le sud du Sahara. Quelles sont les causes de cette maladie ? Comment y faire face ? Comment évaluer le succès des actions préventives ou curatives déjà entreprises ? Où en est la lutte contre cette infection et quelles sont les recommandations nécessaires à son éradication ? Cette expertise collégiale menée par l’IRD, réalisée par une quinzaine de chercheurs à la demande du ministère de la Santé du Mali et de l’Institut d’ophtalmologie tropicale d’Afrique (Mali), s’attache à décrire l’état actuel de la lutte contre cette conjonctivite cécitante d’origine infectieuse. En dressant le bilan des stratégies déjà à l’œuvre, notamment celle du programme CHANCE de l’OMS, cette expertise cherche à définir les conditions et les perspectives de cette maladie.
    Keywords: H1-99 ; méthode de lutte (santé) ; infection ; Afrique subsaharienne ; Mali ; médicament ; assainissement ; médecine traditionnelle ; eau ; antibiotique ; hygiène ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Publication Date: 2024-04-01
    Description: Zum niederländischen Militär in der frühen Neuzeit gehörte es, dass Soldaten regelmäßig gemustert wurden. Die Schlagkräftigkeit des Militärs sollte aufrechterhalten werden. Dazu reisten Musterungskommissare in die Garnisonsorte und begutachteten die Truppen. Neben ihren Amtsgeschäften widmeten die Kommissare sich oftmals intensiv "touristischen" Vergnügungen. Die Berichte geben in niederländischer Sprache daher nicht nur Einblicke in das Musterungswesen selbst, sondern vor allem in das Reisen im 18. Jahrhundert. Dabei lassen sie in deutlicher Form das soziale Leben der Zeit nachvollziehen.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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    Amherst College Press | Amherst College Press
    Publication Date: 2024-04-02
    Description: In 1847, Russian military engineer and diplomat Egor Petrovich Kovalevsky embarked on a journey through what is today Egypt, Sudan, Eritrea, and Ethiopia, recording his impressions of a region in flux. Invited by Egyptian ruler Mohammed Ali to look for gold and construct mines in the area between the Blue and White Nile, Kovalevsky captured the social milieu of both elites and ordinary people as well as compiled a rich record of the Upper Nile’s climate and natural resources. A Journey to Inner Africa, masterfully translated into English for the first time by Anna Aslanyan, is both a tale of encounter between Russia and northern Africa and an important document in the history and development of the Russian imperial project.
    Keywords: Kovalevskīĭ, E. P. (Egor Petrovich), -- 1811-1868 -- Travel -- Africa. ; Kovalevskīĭ, E. P. (Egor Petrovich), -- 1811-1868 -- Travel -- Egypt. ; Russians -- Africa -- History -- 19th century. ; Mining engineering -- Egypt -- History -- 19th century. ; Africa -- History -- To 1884. ; Egypt -- History -- 1798- ; Russia -- Foreign relations -- Africa. ; Africa -- Foreign relations -- Russia. ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::N History and Archaeology::NH History::NHQ History of other geographical groupings and regions
    Language: English
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    Etnográfica Press
    Publication Date: 2024-04-01
    Description: Em 1867, ao prefaciar uma das suas primeiras recolhas de literatura popular, Teófilo Braga, sugerindo uma imagem catastrófica da situação do país, referiu-se desta forma ao seu trabalho: "coligir a poesia popular portuguesa agora, no momento de transe, é como a garrafa ao mar que se atirava nos naufrágios: é para que se saiba que existiu este povo, que também sofreu e cantou". Tal sentimento nacionalista jamais viria a abandonar a sua obra antropológica, o que aliás se explica dada a matriz romântica em que ela assentava. E mesmo quando Teófilo Braga se orientou gradualmente para preocupações de cunho mais científico, isso não significou uma verdadeira ruptura com a perspectiva inicial. São pois os ecos da problemática da identidade nacional, na sua dupla vertente romântica e científica, que podemos reencontrar nestes Contos Tradicionais do Povo Português que, de resto, e independentemente do espírito com que foi concebida e realizada a sua colectânea, propõem ao leitor um conjunto de narrativas cujo fascínio permanece intacto, constituindo além disso um valiosíssimo acervo de informações em áreas que, como a Antropologia e a História das Mentalidades, se dão como objectivo a tarefa de reflectir sobre as múltiplas manifestações das sociedades tradicionais. Após termos procedido à publicação de O Povo Português nos Seus Costumes, Crenças e Tradições, também da autoria de Teófilo Braga, que tem sido considerada a primeira grande obra de conjunto da etnografia nacional, impunha-se esta reedição dos Contos Tradicionais do Povo Português, que decerto formam, juntamente com a recolha de Adolfo Coelho disponível nesta colecção, uma das mais importantes colectâneas de narrativas populares do nosso país. Também na presente reedição se manteve a divisão da obra em dois volumes, tal como sucedia na sua edição original.
    Keywords: H1-99 ; culture populaire ; mythologie ; Portugal ; tradition orale ; contes ; thema EDItEUR::N History and Archaeology::NH History
    Language: Portuguese
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    Milano University Press | Milano University Press
    Publication Date: 2024-04-01
    Description: This volume presents the results of a research project carried out by a team at the University of Milan. Since meeting almost 'for fun' in 2009, this team has grown over the years, and has now a place in international research on the value of playful activities and artifacts. More precisely, this publication is associated with the LALLACT project (Lexicon of Ancient Ludonims, Ludic Activities, and Cultural Tradition), which is dedicated to creating a digital Lexicon of games, starting with the spinning top and blind man's buff. The collected essays represent the outcome of a fruitful interdisciplinary discussion on these two games. More specifically, the miscellaneous volume proposed here is linked to the LALLACT project - Lexicon of Ancient Ludonims project. Ludic Activities and Cultural Tradition, whose ambitious goal is the creation of a prototype of a digital Lexicon of the game, starting from two 'pilot' voices, respectively the game of the spinning top and blind man's buff. The collected essays constitute the outcome, precious and at times unexpected, of a fruitful multidisciplinary discussion on the topics indicated.
    Description: Published
    Description: Il presente volume prende le mosse dalla riflessione scientifica svolta da un gruppo di ricerca dell’Università degli Studi di Milano che, riunitosi quasi ‘per gioco’ nel 2009, è andato negli anni non solo ingrandendosi, ma anche consolidandosi nel panorama internazionale degli interessi scientifici sul valore storico, sociale e culturale delle attività e dei manufatti ludici. Più specificatamente, il volume miscellaneo qui proposto si lega al progetto LALLACT - Lexicon of Ancient Ludonims. Ludic Activities and Cultural Tradition, il cui obiettivo, ambizioso, è la creazione di un prototipo di Lexicon digitale del gioco, a partire da due voci ‘pilota’, rispettivamente il gioco della trottola e della mosca cieca. I saggi raccolti costituiscono l’esito, prezioso e a tratti inatteso, di una proficua discussione multidisciplinare sui temi indicati.
    Keywords: Ludus ; Ludic activities ; Spinning top ; Whipping top ; Blind man’s buff ; thema EDItEUR::N History and Archaeology::NH History
    Language: Italian
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    Institut de la gestion publique et du développement économique
    Publication Date: 2024-04-01
    Description: Les grands corps de l’État n’ont pas toujours bonne presse, mais, en même temps, ils fascinent. Créé au XVIIIe siècle, le corps des Mines n’a cessé de contribuer à la construction économique du pays. Passés par l’École polytechnique et l’École des mines, les ingénieurs du corps ont surveillé et, souvent, directement encadré les secteurs de l’industrie et de l’énergie. Ils ont également joué un rôle éminent dans le domaine scientifique, leurs contributions allant des sciences « dures » (mathématiques et physique, avec Henri Poincaré, chimie avec Henry Le Chatelier) à l’économie, avec Maurice Allais, le seul Français ayant reçu le prix Nobel d’économie, et aussi la sociologie, avec Frédéric Le Play, considéré comme l’un des précurseurs de cette discipline. Industriel dans son essence, industrialiste dans son esprit, ce corps de fonctionnaires a souvent adopté des approches libérales, mais, a contrario, il a souvent impulsé un patriotisme économique de bon aloi dans le cadre de « grands programmes » d’État. Il restait à la richesse de cette expérience, à la fois technique, scientifique et administrative, à se constituer en histoire, à se « conscientiser ». Telle était l’ambition du colloque dont les actes sont présentés dans ce volume. Organisé dans le cadre de la célébration du deux centième anniversaire du décret du 18 novembre 1810 qui a organisé le « Corps impérial des Ingénieurs des Mines », ce colloque historique s’est attaché à mettre en lumière le rôle joué au service de la France par ces hauts fonctionnaires à formation scientifique et technique.
    Keywords: H1-99 ; École polytechnique ; industrie ; géologie ; ingénieurs ; sciences ; mines ; nucléaire ; énergie ; ouvriers mineurs ; environnement ; ressources minérales ; sécurité ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    De Gruyter | De Gruyter Oldenbourg
    Publication Date: 2024-04-02
    Description: While the economic involvement of early modern Germany in slavery and the slave trade is increasingly receiving attention, the direct participation of Germans in human trafficking remains a blind spot in historiography. This edited volume focuses on practices of enslavement taking place within German territories in the early modern period as well as on the people of African, Asian, and Native American descent caught up in them.
    Keywords: Slavery ; Germany ; Atlantic history ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTQ Colonialism and imperialism ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTR National liberation and independence ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTS Slavery and abolition of slavery
    Language: English
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    Éditions de l’École des hautes études en sciences sociales
    Publication Date: 2024-04-01
    Description: L'épistémologie sociale est une analyse de la dimension sociale de la connaissance. Son point de départ est le constat que bien des phénomènes ne nous sont connus que par l'intermédiaire des autres et donc que la connaissance a non seulement des sources directes, celles auxquelles le sujet a lui-même accès, mais aussi des sources indirectes reposant sur la confiance ou sur l'autorité accordée à autrui. Elle s'intéresse donc aux conditions de la transmission de l'information venant d'autrui, et aux relations de confiance et d'autorité épistémiques, notamment dans le domaine des sciences. Mais ses préoccupations sont plus larges et concernent tout ce qui a trait à la dimension sociale de la connaissance: la construction, au cours d'interactions, de justifications recevables ou acceptables; les modes ordinaires de pensée et de raisonnement; ou encore les relations de coopération et de collaboration dans une « communauté épistémique ». De plus elle reprend des questions qui étaient au cœur de la théorie durkeimienne de la connaissance, celle par exemple des croyances collectives, ou l'idée d'un sujet collectif du savoir. Par là elle se rapproche des social studies of science, tout en s'en distinguant par l'adoption d'un point de vue normatif et par le refus du relativisme. Ce volume présente un ensemble de recherches représentatives de ces différentes préoccupations. Elles ont en commun de reconnaître la spécificité de l'idée de normes de la connaissance, et, s'agissant de concevoir la dimension sociale de celle-ci, de se garder des formes radicales de holisme, pour lesquelles les groupes sociaux sont des entités sui generis.
    Keywords: H1-99 ; autorité ; épistémologie ; témoignage ; déférence ; confiance ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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    Publication Date: 2024-04-03
    Description: The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences.
    Keywords: Discipline of representation, History, Semiotics, Science, Technology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society
    Language: Italian , English
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    Publication Date: 2024-04-01
    Description: This monograph provides an overview of research into disasters from a historical perspective, making two new contributions. First, it introduces the field of ‘disaster studies’ to history, showing how we can use history to better understand how societies deal with shocks and hazards and their potentially disastrous outcomes. Second, we introduce historians to the topic of disasters and the field of disaster studies, and explicitly show the relevance of studying past disasters to better understand the social, economic, and political functioning of past societies.
    Keywords: history ; disaster studies ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy.
    Keywords: graphene quantum dot ; targeted drug delivery ; photothermal therapy ; chemo-therapy ; polymeric prodrug ; theranostic nanocomplex ; pH-triggering releasing ; magnetic targeting ; magnetic hyperthermia ; magnetic resonance imaging ; docetaxel ; adenosine receptors ; PLGA ; nanoparticles ; lung cancer ; Notch signaling ; RBPJ protein ; drug repurposing ; fidaxomicin ; acarbose ; schaftoside ; breast cancer ; experimental skin cancer ; entrapment efficacy ; ethosomes ; metformin ; in vitro permeation ; zeta potential ; sesamol ; albumin nanoparticles ; doxorubicin ; oxidative stress ; antioxidants ; tumor-derived membrane vesicles ; cancer therapy ; tumor vaccine ; personalized immunotherapy ; low-density lipoprotein ; nanoparticle ; tumor microenvironment-responsive ; magnetic nanofluid ; improved magnetic resonance imaging ; neutral-responsive Fenton reaction ; enhanced chemodynamic therapy ; brain targeting ; folate receptor ; glioma cancer ; erlotinib ; blood–brain barrier ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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    Waxmann Verlag GmbH
    Publication Date: 2024-04-03
    Description: Dieser Sammelband setzt sich mit den Deutschlandbildern in Belgien bis zum Beginn der deutschen Okkupation im Jahre 1940 auseinander. Betrachtet werden diese aus Sicht unterschiedlicher Geisteswissenschaften wie Philosophie, Literatur, Geschichte, Kunstgeschichte und Musikwissenschaft. Die traditionellen Topoi der deutschen Imagologie, die überall in Europa eine große Resonanz gefunden haben (das romantische Deutschland, das Land der Dichter und Denker, aber ab dem Krieg von 1870 auch das preußische Feindbild), werden dabei in Betracht gezogen. Konstitutiv für den Prozess der Identitätsbildung in Belgien bis zum Ersten Weltkrieg war die deutsch-germanische Komponente, die in der Metapher der sog. âme belge als Kultursynthese zum Ausdruck kam. Der Ausbruch des Ersten Weltkriegs hat hier besonders traumatisch gewirkt, was zur Folge hatte, dass diese partielle „Zugehörigkeit“ Belgiens zur deutschen Kultursphäre drastisch neuevaluiert wurde, unabhängig von der Schaffung eines deutschsprachigen Gebiets in Belgien durch den Versailler Vertrag.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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  • 73
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    Maison des Sciences de l’Homme d’Aquitaine
    Publication Date: 2024-04-01
    Description: Dans son acception classique, dite républicaine, l'espace public traverse une crise dont beaucoup pensent qu'il ne s'en remettra pas. Menacé aussi dans ses manifestations matérielles par la violence, l'Insécurité et les divers communautarismes ou replis sur soi, l'espace public ne semble plus pouvoir répondre aux attentes dont il avait fait l'objet par l'intermédiaire de l'aménagement. Cet ouvrage prend le contre-pied de ces Interprétations, en montrant que, loin d'avoir perdu de sa pertinence, la préoccupation pour l'espace public demeure essentielle pour affronter les défis posés par la société contemporaine, dans la mesure où la réflexion est constamment ramenée à la spatialité qui en fonde l'Intérêt et la portée. Une approche renouvelée de l'espace public est Ici proposée, qui se déploie en associant étroitement trois composantes : la matérialité, la politique, l'action, car nos analyses ne peuvent plus faire l'économie de les considérer séparément. Sa mise à l'épreuve de grands enjeux contemporains montre que l'on peut parler tout autant de régressions que d'émergences.
    Keywords: H1-99 ; communautarisme ; repli identitaire ; spatialité ; émergence ; politique ; régression ; société contemporaine ; espace public ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 74
    Publication Date: 2024-04-06
    Description: The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences.
    Keywords: Discipline of representation, History, Semiotics, Science, Technology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society
    Language: Italian , English
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  • 75
    Publication Date: 2024-04-01
    Description: C’est sur un espace utilisé depuis la fin du ixe siècle, occupé aux environs de l’an mil par une étonnante construction de bois à sol de béton et à vocation funéraire, que s’implante au xiie siècle la nouvelle cuisine de l’abbaye Saint-Philibert de Tournus. Lié au réfectoire voisin, le bâtiment empiète à l’époque sur des niveaux de circulation extérieure. Sa conception architecturale est ambitieuse, avec un plan centré sur un octogone entouré de vastes cheminées à contrecœur semi-circulaire qui évoque des modèles de l’ouest de la France - disparus pour la plupart, à l’exception ou presque de la cuisine de Fontevraud en Anjou. Toutefois, au contraire de ces exemples connus uniquement pour leur architecture, c’est la conservation en place des dépôts d’utilisation intérieurs, compressés à force d’accumulation et de piétinements, qui fait la richesse du spécimen tournusien, illustrant de façon saisissante le quotidien de cette cuisine jusqu’au milieu du xvie siècle. Pendant quatre siècles, c’est autour de grandes langues de cendres témoignant d’une cuisson dans la braise, étalées depuis les quatre foyers jusqu’au milieu de la pièce, que se concentre l’essentiel de l’activité. Les postes de préparation sont trahis par autant de tas de déchets spécialisés : coquilles d’œufs, fragments d’os, écailles de poisson… Une conduite d’eau et un drain de pierres traversent la pièce, portiques ou paravents de bois sont déplacés sans cesse. La permanence de déchets de consommation carnée sur le même site depuis la fin du ixe siècle, l’abondance des restes de poisson dans la cuisine, permettent de retracer l’évolution de l’approvisionnement et de l’alimentation des moines et de leurs familiers laïcs. Quant aux nombreux fragments de poteries, également présents depuis les premiers niveaux, ils offrent sur huit siècles, avec d’autres sites tournusiens, un référentiel de productions en usage dans la région. À cela s’ajoutent quelques restes d’ustensiles en métal, verre ou pierre, tels cette probable tête de robinet des xiie/xiiie siècles ou ce mortier décoré du xive, retrouvé cassé au fond d’une cheminée : ils éclairent, plus ponctuellement, d’autres aspects de la préparation culinaire ou du service de la table. De tout point de vue, en plein contexte monastique, le matériel recueilli trahit les usages d’une population aristocratique. Tels sont les apports d’une fouille minutieuse à l’emplacement de cet édifice crucial de l’abbaye médiévale, un peu oublié à Tournus depuis sa destruction au xviie siècle, mais ressuscité par cet ouvrage finement documenté.
    Keywords: H1-99 ; Moyen Âge ; bâtiment ; abbaye ; cuisine ; moine ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 76
    Publication Date: 2024-04-01
    Description: Les vecteurs des agents du paludisme ou de la leishmaniose, rencontrés lors de voyages dans les régions à climat chaud, s'ajoutant à la transmission par le moustique tigre (Aedes albopictus) des virus chikungunya et de la dengue dans le sud de la France, ont montré l'intérêt d'une réflexion approfondie sur la protection personnelle antivectorielle. En cas d'épidémie, nos concitoyens se protègent individuellement en se procurant sur le marché tout un arsenal de moyens où le meilleur côtoie le pire. Pour donner à chacun des informations sur l'efficacité et l'innocuité de ces moyens de protection, la Société de médecine des voyages et la Société française de parasitologie ont initié cette étude qui a pris la forme de « Recommandations de bonne pratique », en suivant le schéma élaboré par la Haute Autorité de santé. Cet ouvrage rassemble ainsi toutes les données pertinentes, validées et mises en forme pour être utilisées non seulement par les personnels de santé (médecins, pharmaciens, infirmiers), mais aussi par les agents touristiques ainsi que par les particuliers pour se protéger des nuisances et des maladies à vecteurs qui constituent de préoccupants problèmes de santé publique.
    Keywords: H1-99 ; prévention ; recommandations por la pratique clinique ; vecteur de maladies ; moustique ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 77
    Publication Date: 2023-12-21
    Description: It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology.
    Keywords: R5-920 ; Angiogenesis ; Atherosclerosis ; Extracellular vesicles ; Calcification ; Biomarkers ; Cardiovascular disease ; Inflammation ; Exosomes ; Platelets ; Heart valve ; bic Book Industry Communication::M Medicine
    Language: English
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  • 78
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, recent advancements in the field of pediatric tumors are discussed, and novel prognostic markers are critically appraised. Greater understanding of the heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with the potential to provide new prospects for precision medicine in pediatric oncology.
    Keywords: undernutrition ; obesity ; nutritional status ; childhood cancer ; overall survival ; event-free survival ; relapse ; treatment-related toxicity ; review ; sarcoma botryoides ; fertility-sparing surgery ; embryonal rhabdomyosarcoma ; genital tract ; prognosis ; treatment ; local debulking ; neoadjuvant chemotherapy ; radiation ; ovarian cancer ; adolescents ; diagnosis ; therapy ; guidelines ; children ; papillary thyroid cancer ; proto-oncogene B-raf gene (BRAF) ; craniopharyngioma ; recurrence ; risk factors ; youth ; acute lymphoblastic leukemia (ALL) ; child ; genetics ; CDKN2A/2B deletions ; fluorescent in situ hybridization (FISH) ; multiple-ligation probe amplification (MLPA) ; copy-number alterations (CNAs) ; risk stratification ; minimal residual disease (MRD) ; cardiotoxicity ; chemotherapeutics agents ; biomarkers ; omics technology ; medulloblastoma ; tumor ; histologic ; pediatrics ; micro-RNAs ; non-coding RNAs ; molecular subgroup ; stratification ; acute lymphoblastic leukemia ; proteomics ; oncology ; chemotherapy ; cardiac function tests ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 79
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    Presses universitaires de Strasbourg
    Publication Date: 2024-04-02
    Description: Dans sa Démonolâtrie (1595), le procureur général de Lorraine, Nicolas Remy, estime que « Les sorciers appartiennent la plupart du temps au monde des bourgs et des campagnes. ». Cependant, les vauderies survenues à Lyon et Arras au XVe siècle comme les cas de possession du XVIIe siècle sont autant de témoignages de la présence de la sorcellerie dans les villes européennes. Les études de cas et les essais comparatifs réunis dans ce volume montrent qu'en dépit de la diversité des sociétés urbaines, la sorcellerie apparaît comme un révélateur des enjeux de pouvoir qui traversent les villes modernes.Dans sa postface, Carlo Ginzburg insiste sur la portée d'une approche comparatiste, toujours attentive aux écarts à la norme, et souligne l'importance d’aborder les procès de sorcellerie comme une manifestation particulière des tensions sociales et culturelles.
    Keywords: époque moderne ; Europe ; histoire urbaine ; sorcellerie ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history
    Language: French
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  • 80
    Publication Date: 2024-04-01
    Description: Les hauts-plateaux méridionaux du Viêt Nam et du Cambodge connaissent depuis le milieu des années 2000 une forte augmentation des superficies plantées en hévéa. Les booms de l’hévéaculture diffèrent significativement de part et d’autre de la frontière, mais ils sont également étroitement liés dans le contexte d’une intégration régionale des filières et des territoires qui se renforce. Cette transformation est impulsée par le jeu des marchés globalisés et de puissants acteurs étrangers tels que la Chine et la Malaisie, mais les gouvernements nationaux jouent également un rôle important en matière d’accès et d’usage des terres agricoles. L’or blanc et les nouveaux eldorados ne sont pas qu’un enjeu économique ; sont également en jeu les influences et les rapports de force entre les pays de la sous-région du Grand Mékong, à l’image des importantes transactions foncières transnationales. Pour mieux comprendre la transition agraire actuelle impulsée par le boom de l’hévéa, les auteurs de cet ouvrage ont tenu à revenir sur l’histoire, l’époque de la colonisation européenne et les expériences socialistes. L’ouvrage analyse également la capacité des populations locales à résister aux pressions des nouveaux arrivants et la compétition que représentent les plantations d’hévéa de grande taille mécanisées.
    Keywords: H1-99 ; Vietnam ; development ; economics ; Cambodia ; Indochina ; land rights ; integration ; capitalism ; Asean ; land conflicts ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 81
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    Finnish Literature Society / SKS | Finnish Literature Society
    Publication Date: 2024-04-01
    Description: The Finnish novelist Kaarlo (Kalle) Alvar Päätalo’s (1919–2000) main work, the Iijoki series, consists of 26 novels (comprising ca. 17 000 pages) and was written in 1971–1998. In this book the text corpus in Kielipankki concerning Päätalo’s works is introduced to the readers, as well as the possibilities of digital text mining. This book includes scientific articles concerning the works of Kalle Päätalo. It also gives ideas for the research that can be carried out in the future. The authors of this book are researchers in the fields of history, linguistics and literature, respectively. The research results presented in this book speak for the fact that the Iijoki series is a significant source material for future research, for example from the point of view of oral history, language variation, metalanguage, swearing and the reader’s reception. The possibilities for future research seem to be quite plentiful.
    Keywords: authors; Kalle Päätalo; dialects; language of literature; Finnish language literature; Finnish language ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::D Biography, Literature and Literary studies
    Language: Finnish
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  • 82
    Publication Date: 2024-04-01
    Description: This book offers a provocative account of interdisciplinary research across the neurosciences, social sciences and humanities. Setting itself against standard accounts of interdisciplinary 'integration,' and rooting itself in the authors' own experiences, the book establishes a radical agenda for collaboration across these disciplines. Rethinking Interdisciplinarity does not merely advocate interdisciplinary research, but attends to the hitherto tacit pragmatics, affects, power dynamics, and spatial logics in which that research is enfolded. Understanding the complex relationships between brains, minds, and environments requires a delicate, playful and genuinely experimental interdisciplinarity, and this book shows us how it can be done.
    Keywords: neurosciences ; interdisciplinarity ; social sciences ; interdisciplinary research ; integration ; humanities ; Des Fitzgerald ; Epistemology ; Sociology ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 83
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-03-21
    Description: Recently, the development of polymeric materials for biomedical applications has advanced significantly. Polymeric materials are favored in the development of therapeutic devices, including temporary implants and three-dimensional scaffolds for tissue engineering and in vitro disease modelling.Further advancements have also occurred in the utilization of polymeric materials for pharmacological applications, such as delivery vehicles for drug release.We would like to invite you to contribute to this Special Issue. Research topics of interest include, but are not limited to, recent advances related to 3D cell culture, biomaterials, tissue engineering, disease modelling, hydrogel, organoids, drug discovery, bioimaging, cardio-renal, metabolic disease, and stem cell biology.
    Keywords: hydrogels ; crosslinking ; degradable ; gamma (γ)-irradiation ; sterilization ; sterility assurance ; antibacterial ability ; jojoba ; Simmondsia ; chemistry ; liquid wax ; biology ; toxicity ; pharmaceutical/industrial uses ; articular cartilage ; mechanical properties ; tribological properties ; antibacterial ; pathogens ; infectious diseases ; silver nanoparticles ; wound care ; wound dressings ; polymers ; gelatin ; nanofibers ; sponges ; Ag/RGO nanocomposites ; green preparation ; anticancer performance ; potential mechanism ; oxidative stress ; hydrogel ; poloxamer 407 polymer ; poloxamer 407 gel ; transungual drug delivery ; onychomycosis ; ungual penetration enhancer ; Terbinafine ; diafiltration ; SAXS ; aromatic interactions ; poly(sodium 4-styrenesulfonate) ; chlorpheniramine ; polyelectrolyte ; aggregation ; coaxial electrospinning ; extracellular matrix ; myelination ; oligodendrocyte ; water-soluble materials ; orthokeratology lens ; protein deposition ; optical characteristics ; rubbing ; chitosan ; kenaf ; nanocrystalline cellulose ; platelet lysate ; wound healing ; carbohydrate polymers blends ; functional food ; antioxidant activity ; co-microencapsulation ; spray drying ; bacteria viability (Bacillus clausii) ; probiotics ; itraconazole ; self-emulsifying nanovesicles ; transungual ; anti-fungal ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KND Manufacturing industries::KNDP Pharmaceutical industries
    Language: English
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  • 84
    Publication Date: 2024-04-01
    Description: El territorio tiene cada día mayor importancia, tanto en su componente físico como en su dimensión sociocultural. La gestión de los recursos naturales, el problema del acceso a la tierra, la gobernabilidad, las cadenas productivas, las políticas de infraestructura, la cosmovisión campesina, la construcción de identidades y otros son temas relacionados con el espacio y el territorio. El espacio y el territorio han sido investigados desde diversas disciplinas, como la geografía, la economía y la sociología. Sin embargo, todavfa carecemos de propuestas metodológicas intégrales. Por eso, revisando los caminos transitados por la geografía moderna y centrando su preocupación en los conceptos de espacio y territorio, este libro propone una lectura multidimensional y multidisciplinaria del tema, ofreciendo un panorama de los diferentes enfoques, métodos e instrumentas para estudios empiricos, como los métodos estadísticos, cartográficos y, como dice Erwin Galoppo, "ese producto génial de la geografía francesa contemporanea: los coremas".
    Keywords: H1-99 ; planificación espacial ; cartografía ; teledetección ; datos estadísticos ; metodología ; Bolivia ; territorio ; sistema de información espacial ; análisis espacial ; ocupación espacial ; paisaje ; imagen satelital ; thema EDItEUR::N History and Archaeology::NH History
    Language: Spanish
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  • 85
    Publication Date: 2023-12-21
    Description: Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of haematological malignancies as a form of immunotherapy acting through a graft-versus-leukemia (GvL) reaction. This curative allogeneic response can be associated with severe drawbacks, such as frequent and severe graft-versus-host disease (GvHD) and a long-lasting immunodeficiency, especially now with the development of innovative strategies such as umbilical cord blood transplantation or transplants from haplo-identical family donors (Haplo-HSCT). In the long-term follow-up of these patients, severe post-transplant infections, relapse or secondary malignancies may be directly related to persistent immune defects.Reconstitution of the different lymphocyte populations (B, T, NK, NKT) and antigen presenting cells of myeloid origin (monocytes, macrophages and dendritic cells) should be considered not only quantitatively but especially qualitatively, in terms of functional subsets. Immune deficiency leading to an increased susceptibility to infections lasts for more than a year. Although infections that occur in the first month mostly result from a deficiency in both granulocytes and mononuclear cells (MNC), later post-engraftment infections are due to a deficiency in MNC subsets, primarily CD4 T-cells and B-cells. T-cell reconstitution has been extensively studied because of the central role of T-cells in mediating both GvHD, evidenced by the reduced incidence of this complication following T-Cell depletion, and a GvL effect as shown by DLI. In the recent years there has been renewed interest in the role of NK-cells, especially in the context of Haplo-HSCT, and in B-cell reconstitution.This Frontiers Research Topic will provide state of the art knowledge of the mechanisms of immune reconstitution in an allogeneic environment, in order to improve monitoring and therapeutic intervention in allo-HSCT patients.
    Keywords: R5-920 ; RC581-607 ; cell therapy ; Immune reconstitution ; Haplo-SCT ; HSCT ; Thymic function ; bic Book Industry Communication::M Medicine
    Language: English
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  • 86
    Publication Date: 2024-04-01
    Description: The article analyses the morphological means used by the Slovenian dialects of Friuli in adapting loan verbs to their aspectual system in comparison to the traditional means of expressing verbal aspect in the indigenous Slavic lexicon. In relation to verbs of Slavic origin, the formation of aspectual pairs was mainly realised by means of prefixation to the base verb (thereby perfectivising it), whereas with loans from the adjacent Romance varieties (Friulian, Italian, Venetian) suffixation proves more productive (yielding imperfectivisation). The analysis is carried out on the dialect of Resia as well as those from the Torre and Natisone Valleys. Despite some differences, in all three dialects there is generally a strong tendency to integrate loan verbs into the aspectual systems of these varieties. Biaspectual verbs, on the other hand, are relatively rare except for the particular case of the verbs in -inat in Resian.
    Keywords: Slovene dialects of Friuli ; language contact ; loan verbs ; suffixation ; prefixation ; aspectual pairs ; biaspectuality ; thema EDItEUR::N History and Archaeology::NH History
    Language: Italian
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  • 87
    Publication Date: 2024-03-23
    Description: The dissertation analyses dream images in romanticist art, with regards to inherent dreamanalogue strategies in consideration of contemporary dream theory and aesthetics, with a focus on the period between 1820 and 1840. The study does not provide a typological, iconographical or motif-historical collection of samples, but analyses different aspects of selected artworks which represent a wide range in terms of their contextual, formal and topographical heterogeneity, and overcomes the existing stereotypical classification in the context of romanticist art reflection. The study identifies that, beyond the contextual-iconographical dimension, the dream serves as an aesthetical category because it is reflected not only as a motif but also in relation to its dramaturgy. In the romantic awareness of the difficulty of an adequate representation of invisible images, the nonlinear, associative, ciphered, space- and time-simultaneous structure of the dream is adapted as a method, and is staged by varied and differentiated configurations. This is mirrored by comprehensive or formal concepts (genre, technique, media and interdisciplinary), as well as in fragmentary structures (sketches and drawings), in materiality (transparency and colour) or arabesque and combinatory production principles. The study contains three chapters: after a general introduction to the subject, the analysis of the current state of research and the demonstration of the methodology in the first chapter, the second chapter focuses on contemporary dream discourses (especially the theories of Gotthilf Heinrich Schubert and Carl Gustav Carus) and the constitutive role of the philosophy of Friedrich Wilhelm Joseph Schelling. By also involving the literary concepts of dreams the romantic awareness of the deficiency of the visible image compared to the invisible, which forces an avoidance of a mimetic art perception, becomes obvious. The third chapter forms the main body of the study. On the basis of selected dream images it analyses the different artistic strategies and conditions of reception. The first section of the third chapter focuses on artist dream imagery, namely the Musician’s Dream by Caspar David Friedrich, Raphael’s Dream by Franz and Johannes Riepenhausen and the Dream of Erwin von Steinbach by Moritz von Schwind. The analysis indicates that the dreaming artist serves as mise-en-abyme of the dream-analogue productive and reflexive process, and the artwork itself. The second section of chapter three makes landscape spaces accessible as imaginative concepts and projections of emotional states, according to current literature studies. Landscape spaces serve as patterns for reflection processes, which is explored on the basis of The Dreamer by Caspar David Friedrich. The third section of the third chapter focuses on a combinatory and arabesque concept as a dream-analogue and self-reflexive strategy – the collage-like compilation, association and transformation of heterogeneous elements which are analysed on the basis of the artworks Dream of Adam by Moritz von Schwind and The Evening by Clemens Brentano.
    Description: Die Arbeit untersucht Bildstrategien von Traumdarstellungen der deutschen Romantik unter Berücksichtigung der zeitgenössischen Traumtheorie und Ästhetik mit einer Fokussierung auf den Zeitraum zwischen 1820 und 1840. Die Studie geht der Frage nach, ob die Traumdarstellung jenseits ihrer ikonographischen Dimension auch als ästhetisches Konzept fungiert, indem die Dramaturgie des Traumes als Methode eingesetzt wird. Die romantische Präferenz für das Unbewusste – gerade auch hinsichtlich der Kunstproduktion – zeigt sich in der Auseinandersetzung mit der philosophisch-literarischen Frühromantik und kulminiert in einer Ästhetik der inneren Bilder. Diese reflektiert die Darstellbarkeit unsichtbarer Bilder und findet in der alinearen, assoziativen, chiffrierten, raum- und zeitsimultanen Dramaturgie des Traums ihre adäquate Struktur, auch weil sie sich einer homogenen Werkgenese zu widersetzen vermag. Unter Berücksichtigung unterschiedlicher Aspekte analysiert die Arbeit ausgewählte und heterogene Beispiele von Traumdarstellungen, die als Ausdruck dieser (Selbst)reflexion gelesen werden können. Lesen Sie hier die detaillierte English Summary: http://bit.ly/1yxFcVi Lisa Dieckmann promovierte 2013 im Fach Kunstgeschichte an der Universität zu Köln bei Prof. Dr. Susanne Wittekind, ist seit 2005 wissenschaftliche Mitarbeiterin und seit 2008 Geschäftsführerin von prometheus – das verteilte digitale Bildarchiv für Forschung & Lehre am Kunsthistorischen Institut der Universität zu Köln. Sie ist verantwortlich für das DFG-Projekt »Meta-Image – virtuelle Forschungsumgebung für den Bilddiskurs in den Kunst- und Bildwissenschaften«, außerdem Gründungsmitglied des Cologne Center for eHumanties und Sprecherin des Arbeitskreises Digitale Kunstgeschichte.
    Keywords: romantik ; ästhetik ; dream theory ; künste ; traumtheorie ; 19. jahrhundert ; 19th century ; romantic ; arts ; aesthetics ; Friedrich Wilhelm Joseph Schelling ; Philosophie ; thema EDItEUR::A The Arts ; thema EDItEUR::A The Arts::AB The arts: general topics::ABA Theory of art ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::6 Style qualifiers::6R Styles (R)::6RA Romanticism ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTN Philosophy: aesthetics
    Language: German
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  • 88
    Publication Date: 2024-04-03
    Description: The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences.
    Keywords: Discipline of representation, History, Semiotics, Science, Technology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society
    Language: Italian , English
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  • 89
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    transcript Verlag
    Publication Date: 2024-04-01
    Keywords: H1-99 ; Social Work ; Political Sociology ; Metodología Horizontal ; Métodos Colaborativos ; Bielefeld University Press ; Kulturanthropologie ; Latin America ; Horizontal Methodology ; Cultural Anthropology ; Sozialarbeit ; America ; Politische Soziologie ; Collaborative Methods ; Amerika ; Lateinamerika ; thema EDItEUR::N History and Archaeology::NH History
    Language: Spanish
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  • 90
    facet.materialart.
    Unknown
    Maison des Sciences de l’Homme d’Aquitaine
    Publication Date: 2024-04-01
    Description: Très souvent méconnue ou mésestimée dans ses effets les plus graves, la transphobie regroupe de nombreuses discriminations dont sont victimes les transidentités, qu'elles se définissent comme transgenres, transsexuelles ou en tant qu'identités alternatives. Les données recueillies lors d'un travail d'enquêtes et d'entretiens laissent entrevoir que l'acte transphobe peut aussi bien être le fait de la personne lambda que des institutions censées protéger les personnes. Quels sont les mécanismes à l'œuvre ? Quelle est la part du social, du politique voire du culturel dans ce qui concoure à la disqualification de l'autre et de la différence ? Cet ouvrage propose un état des lieux de la question en France et des pistes de réflexion à la lumière des Sciences Humaines et Sociales, tout en relayant et en analysant les témoignages sans ambiguïtés du quotidien des personnes concernées. Une sociologie de la transphobie est un travail de recherche qui pose des questions et propose des pistes de réflexions comme autant de réponses possibles aux processus de discriminations.
    Keywords: H1-99 ; identité alternative ; transphobie ; étude de genre ; transgenre ; identité sexuelle ; discrimination ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 91
    Publication Date: 2024-04-01
    Description: Diplomatic gifts, war prizes, or library treasures of royal and princely libraries—handwritten Qurʾans have also been endowed to mosques, tombs, and other religious complexes to perpetuate and transmit their baraka (divine blessing). Artistic, historic, and religious contexts and materiality of Qurʾans are investigated, from use of costly materials such as gold and parchment to development of special scripts, intricate illuminated designs, and meticulously tooled bindings. This edited collection resulted from a 2016 symposium at the Smithsonian’s Arthur M. Sacker Gallery in conjunction with the exhibition The Art of the Qurʾan: Treasures from the Museum of Turkish and Islamic Arts.
    Keywords: Quran'ic studies ; manuscript studies ; Islamic studies ; Islamic art ; Arabic ; calligraphy ; art history ; illumination ; book arts ; codicology ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 92
    facet.materialart.
    Unknown
    Holzhausen
    Publication Date: 2024-04-01
    Description: Amnesty as an institutionally imposed act of „Forgiving and Forgetting“ is nowadays practised in various fields. Whether it is granted due to security, domestic or financial policy reasons, the freedom and escape from punishment are always in stark contrast to the individual’s compelling responsibility as the basis of our judicial system as well as to the demand for retribution and social peace. This legal institute is not only terminologically harking back to ancient times but also technically. Similar measures are attested throughout the whole of antiquity.
    Description: Ob nun jeweils sicherheits-, innen- oder finanzpolitische Motive zu Grunde liegen, stets stehen Straffreiheit und Straferlass im Spannungsfeld von zwingender Verantwortung des Einzelnen als Grundlage unseres Rechtssystems und der Forderung nach ausgleichender Gerechtigkeit und sozialem Frieden. Das Rechtsinstitut der Amnestie steht nicht nur begrifflich, sondern auch sachlich in antiker Tradition, vergleichbare Maßnahmen sind aus allen Epochen des Altertums nachzuweisen.
    Keywords: Amnesty ; Law of the Ancient Near East ; Law of Pharaonic Egypt ; Greek Law ; Roman Law ; Amnestie ; Recht des Alten Orient ; Recht des pharaonischen Ägypten ; Griechisches Recht ; Römisches Recht ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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  • 93
    Publication Date: 2024-04-01
    Description: Este libro publica una serie de estudios transfronterizos argentino-chilenos y articula trabajos conjuntos de investigadores de ambos lados de la cordillera de la Patagonia. El camino recorrido por las investigaciones atraviesa tres ejes: circuitos, relaciones y representaciones de prácticas políticas y económicas; territorios, itinerarios y expresiones materiales; prácticas culturales y sociales en el marco de la interculturalidad. Los textos fueron puestos a consideración de distintos referentes académicos especializados y buscan constituir una conversación provocadora y provechosa. Por otra parte, pretenden consolidar el imaginario de un territorio común en el tiempo y el espacio, a través de la cordillera como eje integrador y no como límite político nacional.
    Keywords: H1-99 ; socio-cultural practices ; interculturality ; representations ; Patagonia ; territory ; thema EDItEUR::N History and Archaeology::NH History
    Language: Spanish
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  • 94
    facet.materialart.
    Unknown
    Firenze University Press
    Publication Date: 2024-04-01
    Description: The PN Kammalia-Tarawa in an Old Assyrian tablet seems to be the earliest reference of the deity Darawa. The Luwian background this deity is also apparent, e.g., from the plural form DDa-ra-ú-wa-an-zi or from those texts mentioned in CTH 457 and the etymological interpretation of the divine name to the Luwian verb tarāwi(ya)-. Since the early Middle Hittite period Darawa also found her way into the Hattian milieu and as a goddess connected with the family life, she is mentioned several times in festivals for a queen (CTH 646), but also in the Hittite Prayer to the Sun-goddess of the Netherworld (CTH 371) which is – in my opinion – the only Hittite texts mentioning Darawa within the “pantheon of the state”. Texts from the Hurrian and Kizzuwatnaean milieu (e.g., CTH 351) also refer several times to Darawa, but this is clearly the result of a secondary and marginal dissemination of the goddess. In conclusion one might say that Darawa from her Luwian background also came into contact with various milieus of the “Hittite pantheon”, functioning as a goddess providing good (and evil) to humans in everyday life.
    Keywords: Darawa ; Kuduili ; Festival of a Queen ; non-state religion ; Luwian-Hittite contacts ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 95
    Publication Date: 2024-04-01
    Description: The story of how Max Warburg became head of the family-owned bankhouse, although his brother was supposed to take over the business, was often told: When he was 12 years old, the one year older Aby offered Max his birthright for the promise to buy all the books Aby would ever need. Max accepted,and - as he later said - issued "the biggest blank cheque in my life". The paths of life of the two brothers spilt into different directions. Aby built his library into a research institute. Max developed M. M. Warburg & Co., thus the bankhouse becoming one of the most important private banks in Germany. At Simultaneously, they both pursued another goal: the foundation of the university. The brothers were among the early donors of the Hamburg Scientific Foundation (Hamburgische Wissenschaftliche Stiftung). It was all about "Hamburg's mental capacity" ("Hamburgs geistige Zahlungsfähigkeit").
    Keywords: 19th century ; 20th century ; Aby Warburg ; Max Warburg ; Hamburg ; university ; library ; Bankhouse M. M. Warburg & Co. ; foundation ; culture ; science ; politics ; Hamburgische Wissenschaftliche Stiftung ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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  • 96
    Publication Date: 2024-04-06
    Description: The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences.
    Keywords: Discipline of representation, History, Semiotics, Science, Technology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society
    Language: Italian , English
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  • 97
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: This e-book summarises the latest advances in the rheumatic diseases with a focus on the recent efforts of vascular and pulmonary manifestations and anticipate the new and future directions of these research topic. Rheumatic diseases represent a heterogeneous group of severe autoimmune disorders. The present Special Issue aims to provide an overview of the complexity of vascular and pulmonary manifestations of rheumatologic diseases and helps in knowledge to manage them. The eleven published articles here collected underline the complexity of rheumatic diseases and the difficult to treated them. The manuscripts provide an overview of the pathophysiology and current treatment regimes of these disorders, highlighting tools which assist with diagnosis, risk stratification and therapy. Finally, we underline the importance of a multidisciplinary team working using the skills of clinicians, radiologists, and pathologists.
    Keywords: systemic sclerosis ; scleroderma ; interstitial lung disease ; pulmonary function tests ; high-resolution computed tomography ; rheumatic ; pulmonary arterial hypertension ; targeted therapy ; systemic lupus erythematosus ; airway disease ; shrinking lung syndrome ; diffuse alveolar hemorrhage ; pleurisy ; infection ; cardiopulmonary exercise testing ; osteopontin ; connective tissue diseases ; pulmonary involvement ; microvascular involvement ; nailfold capillaroscopy ; rheumatoid arthritis ; interstitial lung diseases ; CX3CL1/fractalkine ; CX3CR1 ; M1 macrophage ; M2 macrophage ; SKG mice ; heart failure ; 3D-echocardiography ; ventricular function ; outcome ; ventricular-arterial coupling ; antifibrotic agents ; COVID-19 ; IPF ; progressive fibrosing ILD ; UIP ; pharmacological interactions ; fibromyalgia ; gastrointestinal symptoms ; probiotic ; VSL#3® ; efficacy ; tolerability ; polymyalgia rheumatica ; vagus nerve stimulation ; inflammatory response ; PMR ; t-vns ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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  • 98
    Publication Date: 2023-12-21
    Description: Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional a/ß T-cells, the available number of germline genes coding for T-cell receptor (TCR) variable elements of γδ T-cells is very small. Moreover, there is a prefential localization of γδ T-cells expressing given Vgamma and Vdelta genes in certain tissues. In humans, γδ T-cells expressing the Vg9Vd2-encoded TCR account for anywhere between 50 and 〉95% of peripheral blood γδ T-cells, whereas cells expressing non-Vd2 genes dominate in mucosal tissues. In mice, there is an ordered appearance of γδ T-cell „waves“ during embryonic development, resulting in preferential localization of γδ T-cells expressing distinct VgammaVdelta genes in the skin, the reproductive organs, or gut epithelia. The major function of γδ T-cells resides in local immunosurveillance and immune defense against infection and malignancy. This is supported by the identification of ligands that are selectively recognized by the γδ TCR. As an example, human Vgamma9Vdelta2 T-cells recognize phosphorylated metabolites („phosphoantigens“) that are secreted by many pathogens but can also be overproduced by tumor cells, providing a basis for a role of these γδ T-cells in both anti-infective and anti-tumor immunity. Similarly, the recognition of endothelial protein C receptor by human non-Vdelta2 γδ T-cells has recently been identified to provide a link for the role for such γδ T-cells in immunity against epithelial tumor cells and cytomegalovirus-infected endothelial cells. In addition to „classical“ functions such as cytokine production and cytotoxicity, recent studies suggest that subsets of γδ T-cells can exert additional functions such as regulatory activity and – quite surpisingly – „professional“ antigen-presenting capacity. It is currently not well known how this tremendous extent of functional plasticity is regulated and what is the extent of γδ TCR ligand diversity. Due to their non-MHC-restricted recognition of unusual stress-associated ligands, γδ T-cells have raised great interest as to their potential translational application in cell-based immunotherapy. Topics of this Research Focus include: Molecular insights into the activation and differentiation requirements of γδ T-cells, role of pyrophosphates and butyrophilin molecules for the activation of human γδ T-cells, role of γδ T-cells in tumor immunity and in other infectious and non-infectious diseases, and many others. We are most grateful to all colleagues who agreed to write a manuscript. Thanks to their contributions, this E-book presents an up-to-date overview on many facets of the still exciting γδ T-cells.
    Keywords: R5-920 ; RC581-607 ; Infection ; Butyrophilin 3A1 ; Tumor-infiltrating lymphocytes ; cancer immunotherapy ; IL-17 ; Pyrophosphates ; bic Book Industry Communication::M Medicine
    Language: English
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  • 99
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    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Manuscripts in this monograph are sorted into five categories: 1. Case Reports: a description of living as a bedridden patient; structured interviews with severely affected ME/CFS patients; how past events contribute to severe ME/CFS; a comparison of moderately ill, severely ill, and very severely ill; case reports of ME/CFS in children. 2. A healthcare provider’s view of managing ME/CFS patients. 3. Characterization of the Severely and Very Severely Affected: (1) the most troubling symptoms; (2) disease severity diminishes capacity for exercise, (3) operationalized definitions of the severely ill and very severely ill; (4) the usefulness of a modified Korean Chalder Fatigue Scale Questionnaire; (5) cardiac dimensions and function in patients; (6) an easier tilt test; and (7) review of sleep studies. 4. Progress in Diagnosis and Treatment: (1) objective measures for grading ME/CFS; (2) a sitting tilt test for orthostatic intolerance; (3) the benefits of IVIgG; (4) risks and protective factors in suicidality; (5) malnutrition and overcoming it; (7) partnerships between patients, caregivers, and providers, and the use of technology; (8) a holistic model of care, “Compassion in Practice; and (9) the effects of suffering, utilizing a four-phase model. 5. Impact of the Disease: (1) a historical perspective; (2) the impact of ME/CFS on psychosocial dynamics; (3) the educational needs of school-aged; and (4) the economic impact of ME/CFS
    Keywords: Adolescence ; Adulthood ; Apnea ; Apnea-hypopnea index ; Bedbound ; Cardiac Function ; Cardiopulmonary Exercise Testing ; Caregivers ; Case Study ; Cerebral Blood Flow ; Chronic Fatigue Syndrome ; Clinical Presentation ; Compassion In Practice ; Diagnosis ; Economic Impact ; Education ; Enteral Nutrition ; EUROMENE ; Europe-Wide ; Grief ; Homebound ; Illness progression ; Immunoglobulin Therapy ; Infection ; Isolation ; IVIgG ; Jarisch&ndash ; Herxheimer Reaction ; Laboratory Tests ; Lived experience ; Loss ; Malnutrition ; Mental Health ; ME/CFS ; Moderately Ill ; Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ; Orthostatic Stress ; Parenteral nutrition ; Patient Assessment ; Patient Management ; Prevention ; Psychological Causation ; Psychosocial ; Severely Ill ; Sleep ; Social Isolation ; Stigma ; Student Learning ; Suicidality ; Symptoms ; Telemedicine ; Trauma ; Treatment ; Tube feeding ; Very Severely III ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
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  • 100
    facet.materialart.
    Unknown
    Maven Publishers
    Publication Date: 2022-04-28
    Description: The development of natural products requires the confluence of the modern techniques and integrated approaches in various fields of science and technology. Intention of this book is to highlight different aspects of globalization of traditional medicine with the focus on some crucial and contemporary issues on validation of natural products. Eminent scientists around the globe have contributed for this book on different issues of ethnopharmacology, traditional medicine and globalization. Given the importance on promotion and development of natural products, this book covers various aspects on revitalization of traditional medicines. The contributors have provided an insight into the modem aspects and future of traditional medicine inspired drug development, validation, safety related quality issues, sustainability and globalization. Bringing together expertise from academia and industry, this edited volume provides an overview of traditional medicine with wisdom and know-how in both innovation and commercialization, placing natural product research in a broader sense for readers. This edited volume contains 68 chapters emphasizing several thrust areas of ethnopharmacology and natural products. A wide diversity of chapters has been contributed by eminent personalities throughout the world including Dr. A. P. J. Abdul Kalam, Sri. Shekhar Dutt, Dr. Marco Leonti, Dr. G. A. Cordell, Dr. R. Verpoorte, Dr. P. J. Houghton, Dr. P. Pushpangadan, Dr. Y. K. Gupta, Dr. A.K.S. Rawat, Dr. S.K. Kulkarni, Dr. Colin W. Wright, Dr. S. C. Mandal, Dr. C. K. Katiyar, Dr. T. K. Mukherjee, Dr. S. Rajan, Dr. G. Schemda, Dr. P. K. Debnath, Dr. Bob Alkin, Dr. Elfin Y. Sukandar, Dr. N. Maity, Dr. A. K. Mitra, Dr. E. Hossain, Dr. H. Fukui, Dr. S.Bhadra, Dr. N. Neema, Dr. H. Mizuguchi, Dr. D. Chattopadhyay, Dr. T. Sen, Dr. Erdem Yesilada, Dr. S.K.Mitra, Dr. S.C. Bachar, Dr. S. Karmakar, Dr. G. B. J. Bailly, Dr. P. Haldar, Dr. Y. Oztruk, Dr. S. Pandit, and others. All representing the-state-of-the-art of the field, and thus would be interesting sources for information. This book will be of enormous help to the undergraduate and postgraduate students, researchers and academia and all others working in the area of Ethnopharmacology and natural product research. It will be an imperative addition to the libraries of technical and administrative personnel in the industries and Universities as a potential resource to update their knowledge.
    Keywords: Globalization ; traditional medicine ; bic Book Industry Communication::M Medicine
    Language: English
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