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  • 1
    Electronic Resource
    Electronic Resource
    Calcium phosphates in pharmaceutical tableting (1993)
    Springer
    Pharmacy world & science 15 (1993), S. 105-115 
    Details
    ISSN: 1573-739X
    Keywords: Calcium phosphates ; Drug compounding ; Excipients ; Particle size ; Physics ; Powders ; Tablets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Ten commercially available calcium phosphates used for direct tableting were evaluated. The particle size distributions, powder properties, Sorption isotherms and pH values of aqueous slurries were compared. All samples showed good or at least sufficient flowability. Scanning electron micrographs illustrated the different kinds of manufacturing and gave hints on their expectable behaviour under compaction pressure. The sorption isotherms of identical chemical substances, which had been manufactured by different methods, differed strongly. This can be related to their specific surface areas. Most of the hydroxylapatites have large surface areas and can absorb up to more than 15% water at 93% relative humidity. Dibasic calcium phosphate dihydrate was non-hygroscopic and absorbed less than 1% water. With the exception of monobasic calcium phosphate monohydrate all calcium phosphates behaved quite neutral in water. Monobasic calcium phosphate monohydrate can be regarded as a solid acid. Although the calcium phosphates are usually stable substances, the role of crystal water in the case of dibasic calcium phosphate dihydrate and monobasic calcium phosphate monohydrate is problematic due to possible interactions with active ingredients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113938
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    Paper (German National Licenses)
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  • 2
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    The meaning of hydrophobicity (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dill, K A -- New York, N.Y. -- Science. 1990 Oct 12;250(4978):297-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco 94143.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2218535" target="_blank"〉PubMed〈/a〉
    Keywords: Energy Transfer ; Physical Phenomena ; Physics ; *Protein Conformation ; Proteins/*chemistry ; Solutions
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 3
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    Superconducting Super Collider. Senate issues a stay of execution (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1992-08-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hamilton, D P -- New York, N.Y. -- Science. 1992 Aug 7;257(5071):737.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1496387" target="_blank"〉PubMed〈/a〉
    Keywords: *Government Agencies ; Physical Phenomena ; Physics ; Politics ; *Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Science, citation, and funding (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-03-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1991 Mar 22;251(5000):1408-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2006414" target="_blank"〉PubMed〈/a〉
    Keywords: Astronomical Phenomena ; Astronomy ; Physical Phenomena ; Physics ; Publishing/*trends ; Research Support as Topic ; Science/*methods ; Sociology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    An ensemble pulsar time (1993)
    In:  CASI
    Details
    Publication Date: 2004-12-03
    Description: Millisecond pulsars are galactic objects that exhibit a very stable spinning period. Several tens of these celestial clocks have now been discovered, which opens the possibility that an average time scale may be deduced through a long-term stability algorithm. Such an ensemble average makes it possible to reduce the level of the instabilities originating from the pulsars or from other sources of noise, which are unknown but independent. The basis for such an algorithm is presented and applied to real pulsar data. It is shown that pulsar time could shortly become more stable than the present atomic time, for averaging times of a few years. Pulsar time can also be used as a flywheel to maintain the accuracy of atomic time in case of temporary failure of the primary standards, or to transfer the improved accuracy of future standards back to the present.
    Keywords: ASTROPHYSICS
    Type: NASA. Goddard Space Flight Center, The 24th Annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting; p 73-86
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    NASA TECHNICAL REPORTS
  • 6
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    Calculations of the outflow velocity of envelopes of cool giants (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: We study the transfer of momentum from photons to dust grains to (molecular) gas in the outflow around cool giants (carbon-stars, Mira variables and OH/IR stars) beyond the radius where the dust grains condense. The problem is circular: radiation pressure determines the outflow velocity of the dust and thus also the dust density; on the other hand the dust density determines, via radiative transfer effects, the spectrum of the photons and thus the effective radiation pressure. This circular problem is solved by a rapidly converging iterative procedure. We compare our predictions with observed properties of a large sample of OH/IR stars and of Miras and find a good qualitative and quantitative agreement. We confirm a conclusion by Wood et al. (1993) that very luminous OH/IR stars in the Large Magellanic Cloud (LMC) owe their low outflow velocity to the low dust-to-gas ratio, a consequence of the low metallicity of the LMC. Similarly we consider a sample of about 100 OH/IR stars within 200 pc from the galactic center that has an average asymptotic giant branch (AGB) luminosity and an uncommonly high value of v(sub out); we conclude that these stars are probably very metal rich, perhaps even more than the stars in the Baade window studied by Rich (1990).
    Keywords: ASTROPHYSICS
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 286; 2; p. 523-534
    Format: text
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    NASA TECHNICAL REPORTS
  • 7
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    The relationship between the magnetic field in the Martian magnetotail and upstream solar wind parameters (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Magnetic field data measured by the MAGMA instrument in the Martian magnetotail lobes are compared with the ram pressure of the upstream solar wind observed by the TAUS instrument in the circular orbits of the Phobos 2 spacecraft. High correlation was found between the magnetic field intensity in the Martian magnetotail lobes and the solar wind ram pressure. From this relationship the average flaring angle of the Martian magnetotail was determined as approximately 13 deg, and the average magnetosonic Mach number was estimated as approximately 5. The observed relationship between the Martian magnetotail magnetic field intensity and the solar wind magnetic field reflects the correlation of the solar wind magnetic field to the ram pressure providing a value of approximately 7 for the average Alfvenic Mach number. The flaring angle obtained for the Martian magnetotail was found to be an intermediate value between the flaring angle of the magnetotail of the Earth and that of Venus at comparable distances.
    Keywords: ASTROPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 99; A9; p. 17,199-17,204
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    NASA TECHNICAL REPORTS
  • 8
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    Focused interplanetary transport of approximately 1 MeV solar energetic protons through self-generated Alfven waves (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: We present a model of the focused transport of approximately 1 MeV solar energetic protons through interplanetary Alfven waves that the protons themselves amplify or damp. It is based on the quasi-linear theory but with a phenomenological pitch angle diffusion coefficient in the 'resonance gap.' For initial Alfven wave distributions that give mean free paths greater than approximately 0.5 AU for approximately 1 MeV protons in the inner heliosphere, the model predicts greater than roughly an order of magnitude amplification (damping) in the outward (inward) propagating resonant Alfven waves at less than or approximately equal to o.3 AU heliocentric distance. As the strength of proton source is increased, the peak differential proton intensity at approximately 1 MeV at 1 AU increases to a maximum of approximately 250 particles (/(sq cm)(s)(sr)(MeV)) and then decreases slowly. It may be attenuated by a factor of 5 or more relative to the case without wave evolution, provided that the proton source is sufficiently intense that the resulting peak differential intensity of approximately 1 MeV protons at 1 AU exceeds approximately 200 particles (/(sq cm)(s)(sr)(MeV)). Therefore, in large solar proton events, (1) one may have to take into account self-amplified waves in studying solar particle propagation, (2) the number of accelerated protons escaping from a flare or interplanetary shock may have been underestimated in past studies by a significant factor, and (3) accelerated protons escaping from a traveling interplanetary shock at r less than or approximately equal to 0.3 AU should amplify the ambient hydromagnetic waves siginificantly to make the shock an efficient accelerator, even if initially the mean free path is greater than or approximately equal to 1 AU.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 424; 2; p. 1032-1048
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    NASA TECHNICAL REPORTS
  • 9
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    One-photon annihilation of thermal positrons with bound atomic electrons (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Direct one-photon annihilation rate of positrons with a bound atomic electron is evaluated in the nonrelativistic limit. The K- and L-shell contributions are estimated including the screening and effective Coulomb repulsion effects. The annihilation rate of thermal positrons is calculated for various temperatures. The total number of one-photon annihilation events in the interstellar medium is discussed. These results provide the directional and structural information for cosmic gamma-ray sources.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 424; 2; p. 988-990
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    NASA TECHNICAL REPORTS
  • 10
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    Origin of tektites (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The origin of tektites has been obscure because of the following dilemma. The application of physical principles to the data available on tektites points strongly to origin from one or more lunar volcanoes; but few glasses of tektite composition have hitherto been reported from the lunar samples. Instead, the lunar silicic glasses consist chiefly of a material very rich in K2O and poor in MgO. The ratio of K2O/MgO is higher in these glasses than in any tektites reported. The solution of the dilemma seems to come from the study of some recently discovered terrestrial deposits of tektite glass with high values of K2O/MgO at the Cretaceous Tertiary boundary. These glasses are found to be very vulnerable to crystallization into sandine or to alteration to smectite. These end products are known and are more abundant than any terrestrial deposits of tektite glass. It seems possible that, in fact, the moon produces tektite glass, mostly of the high K2O-low MgO type; but on Earth these deposits are destroyed. The much less abundant deposits with lower K and higher Mg are observed because they survive. Other objections to the lunar origin hypothesis appear to be answerable.
    Keywords: ASTROPHYSICS
    Type: Meteoritics (ISSN 0026-1114); 29; 1; p. 73-78
    Format: text
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