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  • Articles  (8,484)
  • Polymer and Materials Science  (4,317)
  • Molecular Sequence Data  (4,139)
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  • Medicine  (8,484)
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  • Articles  (8,484)
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  • 1
    Electronic Resource
    Electronic Resource
    Implants for site-specific drug delivery (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 211-212 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020309
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  • 2
    Electronic Resource
    Electronic Resource
    Letter to the Editor (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 213-213 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020310
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  • 3
    Electronic Resource
    Electronic Resource
    Masthead (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991) 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020401
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  • 4
    Electronic Resource
    Electronic Resource
    Erratum (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 215-215 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020311
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  • 5
    Electronic Resource
    Electronic Resource
    Announcement. 2nd international scientific workshop on biodegradable polymers and plastics (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 217-217 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020312
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  • 6
    Electronic Resource
    Electronic Resource
    A new bioactive bone cement: Its histological and mechanical characterization (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 219-229 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: We have developed a bioactive bone cement using CaO—SiO—2—P2O5—CaF2 glass powders and ammonium phosphate solution, and investigaed ist histological and mechanical characteristics in vivo. A bone defect was drilled in the proximal metaphysis of the rat tibia and filled with the bioactive bone cement in paste form or polymethylmethacrylate (PMMA) bone cement in the dough state. The cements were allowed to harden in situ. Histological examinationdemonstrated direct bonding between the new cement and bone by 4 weeks. The bioactive bone cement did not degrade up to 24 weeks postimplantation. The inflammatory reaction to the bioactive bone cement was less intense than the reaction induced by PMMA. Changes in the mechanical properties of the cement in vivo were studied by implanting hardened cylindrical specimens of both types of cement into the hindlimb muscles of ras of rats for 12 weeks. The compressive strength of the bioactive cement increased significantly after implantation, and reached 68 MPa in 1 week and 73 MPa in 4 weeks. These values were comparable to those of PMMA, and were maintained up to 12 weeks after implantation. This bioacive bone cement hadens in situ within a few minutes with negligible rise of temperature and can be easily handled as a paste for filling bone cavities of different shapes. In addition, this cement has good osteoconductive and bone bonding potential and fairly high mechanical strength. Therefore, this new cement could be used both as a bioactive bone cement and bone defect filler.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020402
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  • 7
    Electronic Resource
    Electronic Resource
    Intraosseous anchorage of the carbon fiber composite ligament by bony ingrowth (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 241-242 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: It is common experience that carbon fiber braids, which are passed through osseous tunnels, are not incorporated by osteointergration. Rather, they are separated from the boy walls of the tunnels by a granulomatous-cicatrizing interface membrane. In the exceptional case, however, Bony ingrowth into the braid occurs without an intervening soft tissular layer. Bony ingrowth may be contingent on the stability of the carbon fiber braid within the osseous tunnel.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020404
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  • 8
    Electronic Resource
    Electronic Resource
    An investigation of bioactive glass powders by sol-gel processing (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 231-239 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Bioactive glass powders, with a composition of SiO2-CaO-P2O5,have been successfully synthesized via a sol-gel process at considerably loer temperatures than required for conventional melting method. Bioactive glass powders made via conventional methods form an interfacial bond wih none when they are implanted. Bonding is correlated with the formation of a surface hydroxyapatite layer. This study examinded the formation of a hydroxyapatite layer in Tris-buffered solution as a function of SiO2 content of sol-gel derived powders. A FT-IRRS technique was used to monitor the formation of the hydroxyapatite on the surface of the powders. X-ray diffraction analysis and BET were also used to characterize the chemical and physical properties of the sol-gel derived bioactive powders. It was discovered that: (a) the rate of hydroxyapatite formation decreased wih increasing SiO2 content for powders whose SiO2 content was less than 90 mol%; (b) a hydroxyapatite film does not form for the powders whose SiO2 content is more than 90 mol%; (c) the SiO2 limit, beyond which the powders lost their bioactivity, was much higher for bioactive glass powders mad through sol-gel process (90%) than those made by conventional melting methods (60%). These results indicate that it is possible to significantly expand the bioactive composition range through microstructural control made possible by sol-gel processing techniques.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020403
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  • 9
    Electronic Resource
    Electronic Resource
    Pulp capping with synthetic hydroxyapatite in human premolars (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 243-250 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Classically, calcium hydroxide is used as a pulp capping agent in humans to form a dentinal bridge over vital dental pulp tissue. The aim of the present study was to determine whether synthetic hydroxyapatite could be used as a substitute. For this purpose, pulp capping with microsized hydroxyapatite (mean size = 38 nm ± 15 nm) was done under lacal anesthesia in 12 normal premolars, to be extracted for orthodontic purposes form 12 different young patients, having given their informed consent. Clinically, the healing was uneventful in all patients, having given their informed consent. Clinically, the healing was uneventful in all patients. Half of the teeth were extracted at 3 months and the other half at 6 months. The pulps were studied under light microscopy and under scanning and transmission electron microscopy using nondecalcified sections. In all cases, a continuous, well-calcified bridge was observed and no inflammatory cells were present in the residual pulp. In some cases denticles containing some synthetic hydroxyapatite crystals were found in the radicular pulp. The calcified bridge was made up by osteodentine and near the pulp tubular dentine with a layer of predentine and odontoblasts were noted. Odontoblastic processes were lacated in deninal tubules and the intertubular dentine showed interwoven calcified collagen fibrils and hydroxyapatite crystals with a mean length of 0.1 μm along their c axis.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020405
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  • 10
    Electronic Resource
    Electronic Resource
    Nanocrystalline epsein-barr virus decoys (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 251-259 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A novel biotechnology is introduced by way of the successful synthesis of nanocrystalline Epstein-Barr virus (EBV) decoys having specific in vivo immunogenie activity. Assembled from ultrafine suface modified tin oxide and purified DNA-free isolated EBV envelope proteins, the decoys consisted of 〉150 nm units whose electophoretic mobilities were similar to whole EBV; whose outer coats were strongly immunoreactive with murine monoclonal anti-EBV antibodies; and which elicited immunospecific niutralizing anti-EBV antibodies in the rabbit. The development of this carier techonology for vaccine preparations is suggested.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020406
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